Inhalation anesthesia with isoflurane in a black jaguar (Panthera onca) for surgical repair of a fractured mandible

A black jaguar (Panthera onca) was anesthetized with a combination of medetomidine, ketamine and isoflurane in oxygen for radiological examination and surgical repair of a fractured mandible. Since a non-domesticated cat is potentially dangerous, induction of anesthesia was performed by intramuscular injection using a mechanical squeeze cage. The cardiopulmonary parameters during anesthesia remained within normal ranges; only a small increase in the respiration rate was recorded 75 minutes after intubation. This hyperventilation was treated with buprenorphine (for additional analgesia) and an increased inspiratory fraction of isoflurane. Recovery was rather slow after 165 minutes of general anesthesia, so atipamezole was administered. Ten minutes after the intramuscular injection of atipamezole, the animal started to recover. Meloxicam and buprenorphine were used for post-operative analgesia

Medial compartment disease in a young Large Munsterlander

Medial compartment disease (MCD) is a recently recognized elbow disorder in dogs and refers to extensive cartilage erosions of the medial compartment of the elbow joint. This report describes a case of MCD in a 10-month-old Large Munsterlander that was presented with right frontleg lameness. Based on signalement, history and radiographic examination, there was a strong suspicion of a fragmented coronoid process (FCP) of the right elbow. However, arthroscopic examination revealed extensive cartilage erosions of the medial part of the humeral condyle and the medial coronoid process in addition to a small coronoid fragment (FCP) and a small OCD-like lesion. After the arthroscopic treatment, the dog did not improve. Neither did additional treatment with autologous conditioned plasma (Arthrex ACP (R)) lead to a substantial improvement. Finally, the dog was euthanized because of persistent lameness

Brain perfusion, part 2: anesthesia and brain perfusion in small animals

Sedatives and anesthetics can influence cerebral metabolism and respiratory and cardiovascular dynamics, which results in changes in cerebral perfusion. This is of major importance when functional brain imaging techniques are used to measure cerebral blood flow or to evaluate neurotransmitter systems, and also during neurosurgery. In the present review, the influences on brain perfusion of different sedatives including opioids and anesthetics commonly used in veterinary medicine are summarized

Chirurgische behandeling van het discusgeassocieerd Wobblersyndroom door middel van een standaard ventraalslottechniek: een retrospectieve studie van 12 gevallen

There is much controversy about the treatment of disc associated wobbler syndrome. This retrospective study describes the clinical evolution of 12 dogs treated surgically by a standard ventral slot technique. The duration of follow-up ranged from 1 to 59 months. Nine of the 12 dogs clinically recovered. However, 6 of these 9 dogs developed a second episode of clinical signs. Two of these dogs could be further managed by conservative treatment. The 4 other dogs were euthanized. The results of this study are compared to the literature. Special attention is given to inclusion criteria and follow-up data

De behandeling van een omvangrijke ribtumor bij een hond

A 12-year-old English Cocker spaniel was referred because of front leg lameness due to a mass on the right cranioventral thoracic wall. Radiographic examination showed that the limited external mass had a large intrathoracic component. The patient was staged, and based on the results of computed tomography, surgery was planned and the tumor was removed en bloc. An osteosarcoma with metastasis in the regional lymph nodes was diagnosed on histopathology. Consequently, chemotherapy was instituted. The disease-free period lasted four months, after which respiratory discomfort developed due to pulmonary metastases. The dog was euthanized five months after surgery. This case illustrates that a sufficiently aggressive, multimodal treatment may prolong life expectancy in case of an advanced, malignant tumor

Designing a Good Life: A Matrix for the Technological Mediation of Morality

Technologies fulfill a social role in the sense that they influence the moral actions of people, often in unintended and unforeseen ways. Scientists and engineers are already accepting much responsibility for the technological, economical and environmental aspects of their work. This article asks them to take an extra step, and now also consider the social role of their products. The aim is to enable engineers to take a prospective responsibility for the future social roles of their technologies by providing them with a matrix that helps to explore in advance how emerging technologies might plausibly affect the reasons behind people’s (moral) actions. On the horizontal axis of the matrix, we distinguished the three basic types of reasons that play a role in practical judgment: what is the case, what can be done and what should be done. On the vertical axis we distinguished the morally relevant classes of issues: stakeholders, consequences and the good life. To illustrate how this matrix may work in practice, the final section applies the matrix to the case of the Google PowerMeter