Dryland adaptation in Northeast Brazil: Lessons from a community-based pilot project

Family farmers in Brazil’s semi-arid region (the Sertão) are highly vulnerable to climate change. In this context, the community-based Adapta Sertão (“adapt Sertão” or “adapt the Sertão”) pilot project aims to strengthen the adaptive capacity of such families in the region of Pintadas, State of Bahia, through integration of immediate livelihood needs with community empowerment and market-based incentives. This short paper discusses the project’s main components, its results and constraints since implementation in 2006. The project is found to have contributed to rural livelihood improvement of its beneficiaries, especially where related to local capacity building. However, the impacts of the strongest drought recorded in the last 50 years continue to affect beneficiaries. CBA in semiarid Brazil may thus need to interact more broadly with those public policies, plans and programs help reduce vulnerability to climatic, social, environmental and economic stressors in general, in order to help family farmers better to sustainably adapt to future climate change.Los agricultores familiares en la región semiárida de Brasil (Sertão) son muy vulnerables al cambio climático. En este contexto, el proyecto piloto basado en la comunidad Adapta Sertão («adaptar Sertão» o «adaptar la región de Sertão») está dirigido a fortalecer la capacidad de adaptación de dichas familias en la región de Pintadas, Estado de Bahía, a través de la integración de las necesidades de subsistencia inmediatas mediante capacitación de la comunidad e iniciativas basadas en el mercado. Este informe breve aborda los principales elementos del proyecto, sus resultados y limitaciones desde su implementación en 2006. Se ha descubierto que el proyecto ha contribuido a la mejora de las condiciones de subsistencia de sus beneficiarios en regiones rurales, en especial, en relación con la construcción de capacidades locales. No obstante, el impacto de la sequía más importante registrada en los últimos 50 años sigue afectando a los beneficiarios. De este modo, la CBA en la región semiárida de Brasil tendrá que interactuar en mayor profundidad con políticas, planes y programas para la reducción de la vulnerabilidad a factores de estrés climáticos, sociales, medioambientales y económicos en general, a fin de ayudar a los agricultores familiares a adaptarse de una forma más sostenible al cambio climático futuro.Les familles d'exploitants agricoles du Sertão, région semi-aride du Brésil, sont très vulnérables au changement climatique. Dans ce contexte, le projet pilote communautaire Adapta Sertão ("adapter le Sertão") vise à renforcer la capacité d'adaptation de ces familles dans la région de Pintadas, dans l'Etat de Bahia, par l'intégration des besoins de moyens de subsistance immédiats via l'autonomisation des communautés et des incitations commerciales. Ce court article expose les principaux éléments du projet, ses résultats et ses contraintes depuis sa mise en oeuvre en 2006. Ce projet a contribué à améliorer la vie rurale de ses bénéficiaires, en particulier concernant le développement des capacités locales. Toutefois, les conséquences de la plus forte sécheresse qu'ait connu le Brésil au cours de ces 50 dernières années, continuent d'affecter les bénéficiaires. L'adaptation communautaire dans les régions semi-arides du Brésil peut ainsi passer par une interaction à plus grande échelle avec ces politiques, plans et programmes publics visant à réduire la vulnérabilité aux facteurs de stress climatiques, sociaux, environnementaux et économiques en général, afin de faciliter l'adaptation des familles d'exploitants agricoles au changement climatique futur de manière durable

Wind turbines in Brazil and Germany: an example of geographical variability in life-cycle assessment

A life-cycle assessment of a single product can produce substantially varying results that depend on the location of production. It is the aim of this study to provide an example of this geographical variability by examining the energy and CO2 embodied in a particular wind-turbine manufactured in Brazil and in Germany. Our results demonstrate the importance of adequately considering the background system of the local economy.Life-cycle assessment Wind turbines Brazil Germany Energy CO2

Dryland adaptation in Northeast Brazil: Lessons from a community-based pilot project

Family farmers in Brazil’s semi-arid region (the Sertão) are highly vulnerable to climate change. In this context, the community-based Adapta Sertão (“adapt Sertão” or “adapt the Sertão”) pilot project aims to strengthen the adaptive capacity of such families in the region of Pintadas, State of Bahia, through integration of immediate livelihood needs with community empowerment and market-based incentives. This short paper discusses the project’s main components, its results and constraints since implementation in 2006. The project is found to have contributed to rural livelihood improvement of its beneficiaries, especially where related to local capacity building. However, the impacts of the strongest drought recorded in the last 50 years continue to affect beneficiaries. CBA in semiarid Brazil may thus need to interact more broadly with those public policies, plans and programs help reduce vulnerability to climatic, social, environmental and economic stressors in general, in order to help family farmers better to sustainably adapt to future climate change

West German Study PlanB Trial: Adjuvant Four Cycles of Epirubicin and Cyclophosphamide Plus Docetaxel Versus Six Cycles of Docetaxel and Cyclophosphamide in HER2-Negative Early Breast Cancer

PURPOSE The West German Study Group PlanB trial evaluated an anthracycline-free chemotherapy standard (six cycles of docetaxel and cyclophosphamide [TC]) in the routine treatment of human epidermal growth factor receptor 2-negative early breast cancer (EBC). PATIENTS AND METHODS Patients with pT1 to pT4c, all pN+, and pN0/high-risk EBC were eligible. High-risk pN0 was defined by one or more of the following: pT greater than 2, grade 2 to 3, high urokinase-type plasminogen activator/plasminogen activator inhibitor-1, hormone receptor (HR) negativity, and less than 35 years of age. After an early amendment, all HR-positive tumors underwent recurrence score (RS) testing, with chemotherapy omission recommended in RS less than or equal to 11 pN0 to pN1 disease. Patients were randomly assigned to four cycles of epirubicin (E)(90)/cyclophoshamide (C)(600) followed by four cycles of docetaxel (T)(100) or six cycles of T75C600 (administered once every 3 weeks). The primary end point was disease-free survival (DFS); secondary end points were overall survival (OS) and safety. The protocol specified P = .05 for a noninferiority margin of 4.4% for all patients combined. RESULT Of the 3,198 registered patients, 348 (RS <= 11) omitted chemotherapy, and 401 were not randomly assigned. The intention-to-treat population included 2,449 patients (1,227 EC-T v 1,222 TC: postmenopausal, 62.2% v60.8%; pNO, 58.2% v59.5%; pT1, 57.6% v52.3%; HR positive, 81.4% v82.2%; RS greater than 25 [in H.R-positive patients], 26.2% v 27.5%). Within the safety population (1,167 v 1,178 patients), 87.5% v 93.0% completed therapy. After a 60-month median follow-up, 5-year outcomes were similar in the EC-T and TC arms (DFS, 89.6% [95% CI, 87.9% to 91.5%] v89.9% [95% CI, 88.1% to 91.8%]; OS, 94.5% [95% CI, 93.1% to 95.9%] v94.7% [95% CI, 93.3% to 96.1%]). The DFS difference was within the noninferiority margin of the original trial design. Five treatment-related deaths were reported for TC (one for EC-T), despite a trend toward more-severe adverse events in the latter. Interaction analysis revealed no predictive trends with respect to key factors, including triple-negative, luminal A/B-like, pN, age, and RS status. CONCLUSION In the West German Study Group PlanB trial, 5-year outcomes for TC and EC-T were equally excellent. Six cycles of TC is an effective/safe option in human epidermal growth factor receptor 2-negative EBC with pN0 high genomic risk or pN1 EBC with genomically intermediate- to high-risk disease. (C) 2019 by American Society of Clinical Oncolog