27 research outputs found
β-Carboline and diazepam effect on the degradation of enkephalin by the human blood aminopeptidase
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MDCT findings in small bowel obstruction: implications of the cause and presence of complications on treatment decisions
No full textPharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons
No full textCardiac Looping and the Left-Right Axis: Integrating Morphologic, Molecular, and Genetic Analyses of Vertebrate Left-Right Asymmetry
No full textHTRA proteases: regulated proteolysis in protein quality control
No full textControlled proteolysis underlies a vast diversity of protective and regulatory processes that are of key importance to cell fate. The unique molecular architecture of the widely conserved high temperature requirement A (HTRA) proteases has evolved to mediate critical aspects of ATP-independent protein quality control. The simple combination of a classic Ser protease domain and a carboxy-terminal peptide-binding domain produces cellular factors of remarkable structural and functional plasticity that allow cells to rapidly respond to the presence of misfolded or mislocalized polypeptides
Status Creation and Maintenance among the Delaware Valley Elite: The Rise and Fall of the Field Family
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