9 research outputs found
Ion channeling studies on mixed phases formed in metalorganic chemical vapor deposition grown Mg-doped GaN on Al₂O₃(0001)
Author name used in this publication: W. K. FongAuthor name used in this publication: C. SuryaVersion of RecordPublishe
Application of a graphene buffer layer for the growth of high quality SnS films on GaAs(100) substrate
Tin mono-sulfide (SnS) thin films have been grown by molecular beam epitaxy (MBE) on two different substrates, GaAs (100) and soda lime glass at 400°C. High resolution X-ray Diffraction (HXRD) and Scanning Electron Microscopy (SEM) are used to characterize the structural properties of the as grown SnS films. By introducing a graphene buffer layer between the SnS thin film and the substrate, the XRD rocking curve's full width at half maximum (FWHM) of the SnS film grown on GaAs (100) and soda lime glass decrease from 2.92° to 0.37° and from 6.58° to 2.04° respectively, indicating a significant improvement of SnS thin films.Department of Applied PhysicsDepartment of Electronic and Information EngineeringAuthor name used in this manuscript: W. K. FongAuthor name used in this manuscript: C. SuryaRefereed conference pape
Molecular beam epitaxy growth of high quality p-doped SnS van der Waals epitaxy on a graphene buffer layer
Author name used in this publication: W. K. FongAuthor name used in this publication: C. Surya2011-2012 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Sequence analysis of Candida albicans phosphoribosyl-aminoimidazole carboxylase (ADE2) gene
The nucleotide sequence of the Candida albicans ADE2 gene, which encodes phosphoribosyl aminoimidazole carboxylase, has been determined. The sequence possesses an uninterrupted open reading frame of 1704 nucleotides corresponding to 568 amino acid residues. The deduced amino acid sequence shares a high degree of homology with ADE2 homologues in other fungal species including Saccharomyces cerevisiae, Pichia methanolica, Schwanniomyces occidentalis and Schizosaccharomyces pombe. Three regions of amino acid sequence were highly conserved among all reported ADE2 genes. The hexanucleotide TGACTC characteristic of genes involved in purine and amino acid biosyntheses is located in front of putative TATA boxes in the promoter region. The GenBank Accession Number of this gene is U75582.link_to_subscribed_fulltex
Application of a graphene buffer layer for the growth of high quality SnS films on GaAs (100) substrate
Author name used in this manuscript: W. K. FongAuthor name used in this manuscript: C. SuryaRefereed conference paper2011-2012 > Academic research: refereed > Refereed conference paperAccepted ManuscriptPublishe
K-ras mutation, HPV infection and smoking or alcohol abuse positively correlate with esophageal squamous carcinoma
The Ras/Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates including growth, survival and apoptosis. The aim of this study was to determine the incidence of B-raf, Kirsten-ras (K-ras) and Neuroblastoma-ras (N-ras) gene mutations in esophageal squamous cell carcinoma (ESCC) in the Greek population. DNA was extracted from 30 ESCC and 32 normal esophageal specimens and screened for V600E B-raf, and K-ras/N-ras codon 12 mutations, by PCR-RFLP based analysis. Among the genes tested, only the heterozygous K-ras mutation was detected in 5 out of the 30 ESCC specimens (16%), whereas no mutation was found in the normal esophageal tissue (P < 0.022). The normal samples were screened negative for N-ras and V600E B-raf mutations. The increased risk of esophageal cancer was correlated with tobacco use (OR=3.5, P < 0.023) and alcohol abuse (OR=7.22, P < 0.001), accompanied with the high incidence of the k-ras codon 12 mutation (22%, OR=1.77 and 21%, OR=1.52), respectively. A similar positive association was seen in human papilloma virus (HPV)-infected patients (OR=5.66, P < 0.003). Our overall findings demonstrate that the mutational activation of the K-ras gene, HPV infection and tobacco or alcohol abuse, can be considered independently or in combination as high risk factors for ESCC development