67 research outputs found
Solid lipid nanoparticles of irbesartan: preparation, characterization, optimization and pharmacokinetic studies
Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms
Basic Science Considerations in Primary Total Hip Replacement Arthroplasty
Total Hip Replacement is one of the most common operations performed in the developed world today. An increasingly ageing population means that the numbers of people undergoing this operation is set to rise. There are a numerous number of prosthesis on the market and it is often difficult to choose between them. It is therefore necessary to have a good understanding of the basic scientific principles in Total Hip Replacement and the evidence base underpinning them. This paper reviews the relevant anatomical and biomechanical principles in THA. It goes on to elaborate on the structural properties of materials used in modern implants and looks at the evidence base for different types of fixation including cemented and uncemented components. Modern bearing surfaces are discussed in addition to the scientific basis of various surface engineering modifications in THA prostheses. The basic science considerations in component alignment and abductor tension are also discussed. A brief discussion on modular and custom designs of THR is also included. This article reviews basic science concepts and the rationale underpinning the use of the femoral and acetabular component in total hip replacement
The effect of posterior and lateral approach on patient-reported outcome measures and physical function in patients with osteoarthritis, undergoing total hip replacement: a randomised controlled trial protocol
Die reflektorische Selbststeuerung des Kreislaufs unter dem Einfluß hydrostatischer Druckeinwirkungen auf den Thorax
- …