Optimal nutrition and the ever-changing dietary landscape : a conference report

The field of nutrition has evolved rapidly over the past century. Nutrition scientists and policy makers in the developed world have shifted the focus of their efforts from dealing with diseases of overt nutrient deficiency to a new paradigm aimed at coping with conditions of excess—calories, sedentary lifestyles and stress. Advances in nutrition science, technology and manufacturing have largely eradicated nutrient deficiency diseases, while simultaneously facing the growing challenges of obesity, non-communicable diseases and aging. Nutrition research has gone through a necessary evolution, starting with a reductionist approach, driven by an ambition to understand the mechanisms responsible for the effects of individual nutrients at the cellular and molecular levels. This approach has appropriately expanded in recent years to become more holistic with the aim of understanding the role of nutrition in the broader context of dietary patterns. Ultimately, this approach will culminate in a full understanding of the dietary landscape—a web of interactions between nutritional, dietary, social, behavioral and environmental factors—and how it impacts health maintenance and promotion.</p

Value Operations Methodology for Value Driven Design: Medium Range Passenger Airliner Validation

This paper gives insight in the development of a Value Operations Methodology (VOM) that can be used to support Value Driven Design (VDD). The VOM establishes expressions for operational value levers that are incorporated into a weighted value function. This value function is then used to optimize the design variables that are incorporated into it so that the design process is actively driven by value assessments that provide design decision metrics. However, the VOM is generic in nature and has a much wider range of influence to the design process for any engineering product. The methodology is verified by means of a case study, analyzing the value difference between the Boeing 737-200, Boeing 737-800, Embraer ERJ-145 and the Airbus 319 as part of a use-case study. In fact, the fundamental conclusion from the work presented is actually that VDD simply promotes the sustained application of the main utility values that were originally recognised but which, due to the complexity of the product and enterprise, tends to be disaggregated into isolated requirements. Ultimately, this leads to optimisation at a sub-system level and that is especially unacceptable for a complex system (with many sub-systems), whereas the re-focus of VOM helps to significantly shift the design effort back to creatively solving the main goal, rather than simply and somewhat robotically making sure the requirements are satisfied. The verification and validation work presented is recognised as indicative but the authors believe that it is extremely significant in pointing towards the potential gains from sustaining a more holistic appraisal and approach through-out the design process. Notwithstanding, the key message of the paper is the need for value modelling within engineering so that we are in control of the consequences of what we are actualising, where value is realised through operational delivery and excellence! This paper has presented a broad methodology in opening up a significantly different approach to aircraft design that may well still be economically driven but incorporating drivers of a much more holistic cause: proactively rather than reactively