Toward a sustainable, participatory and inclusive wild meat sector

The meat of wild species, referred to in this report as ‘wild meat’, is an essential source of protein and a generator of income for millions of forest-living communities in tropical and subtropical regions. However, unsustainable harvest rates currently endanger the integrity of ecosystems and threaten the livelihoods of many vulnerable households. This report, produced in response to a call from the Secretariat of the Convention on Biological Diversity (CBD), is a technical tool to help users guide actions towards a more sustainable wild meat sector. Here, we present an extensive compilation of the current knowledge on wild meat use, drivers and impacts, and provide recommendations on how to improve wild meat governance and management.In all tropical and subtropical regions, greater wildlife offtakes are being enabled by advances in hunting technologies, as well as the increased penetration of new lands by infrastructure, logging, mining and agriculture. Consumers in fast-growing urban centers largely drive demand for wild meat, where it is eaten as a luxury item rather than as a food staple. This greater pressure from large towns and cities has had significant impacts on wildlife populations and ecosystem integrity. In turn, this jeopardizes the financial ‘safety nets’ and food security of remote rural and indigenous communities, for whom wild meat can account for much of their dietary protein, as well as an important source of other nutrients.Key to the success of sustainable management is ensuring that wild meat use is considered a cross-sectoral issue; firmly incorporated in national resource and land-use planning. The success of management strategies will depend on an enabling environment at the national level. In many countries a key first step will be the revision of national hunting laws and land tenure governance systems in consultation with multiple stakeholders. Research efforts must focus on producing science-based evidence that governments, communities, NGOs and industries can use to improve management policies and practices.The creation of a sustainable wild meat sector requires interconnected interventions along the entire value chain – focused on local hunting communities, urban consumers and wider society. Well-designed, participatory approaches can enable sustainable management of wild meat supply for local communities, but only if this is strongly complemented by approaches that aim to reduce urban deman

Roll Maneuver Control of UCAV Wing Using Anisotropic Piezoelectric Actuators

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76333/1/AIAA-2002-1720-656.pd

SMAD6 variants in craniosynostosis: genotype and phenotype evaluation

Purpose: Enrichment of heterozygous missense and truncating SMAD6 variants was previously reported in nonsyndromic sagittal and metopic synostosis, and interaction of SMAD6 variants with a common polymorphism near BMP2 (rs1884302) was proposed to contribute to inconsistent penetrance. We determined the occurrence of SMAD6 variants in all types of craniosynostosis, evaluated the impact of different missense variants on SMAD6 function, and tested independently whether rs1884302 genotype significantl

Late Ebola virus relapse causing meningoencephalitis: a case report

Background: There are thousands of survivors of the 2014 Ebola outbreak in west Africa. Ebola virus can persist in survivors for months in immune-privileged sites; however, viral relapse causing life-threatening and potentially transmissible disease has not been described. We report a case of late relapse in a patient who had been treated for severe Ebola virus disease with high viral load (peak cycle threshold value 13·2). Methods: A 39-year-old female nurse from Scotland, who had assisted the humanitarian effort in Sierra Leone, had received intensive supportive treatment and experimental antiviral therapies, and had been discharged with undetectable Ebola virus RNA in peripheral blood. The patient was readmitted to hospital 9 months after discharge with symptoms of acute meningitis, and was found to have Ebola virus in cerebrospinal fluid (CSF). She was treated with supportive therapy and experimental antiviral drug GS-5734 (Gilead Sciences, San Francisco, Foster City, CA, USA). We monitored Ebola virus RNA in CSF and plasma, and sequenced the viral genome using an unbiased metagenomic approach. Findings: On admission, reverse transcriptase PCR identified Ebola virus RNA at a higher level in CSF (cycle threshold value 23·7) than plasma (31·3); infectious virus was only recovered from CSF. The patient developed progressive meningoencephalitis with cranial neuropathies and radiculopathy. Clinical recovery was associated with addition of high-dose corticosteroids during GS-5734 treatment. CSF Ebola virus RNA slowly declined and was undetectable following 14 days of treatment with GS-5734. Sequencing of plasma and CSF viral genome revealed only two non-coding changes compared with the original infecting virus. Interpretation: Our report shows that previously unanticipated, late, severe relapses of Ebola virus can occur, in this case in the CNS. This finding fundamentally redefines what is known about the natural history of Ebola virus infection. Vigilance should be maintained in the thousands of Ebola survivors for cases of relapsed infection. The potential for these cases to initiate new transmission chains is a serious public health concern