Resumption of postpartum ovarian cyclicity in dairy cows and its relationship with acute phase proteins, uterine health and lipolysis during the transition period.

O objetivo deste estudo foi avaliar a retomada do pós-parto ciclicidade e sua relação com proteínas de fase aguda, a saúde uterina e lipólise durante o período de transição de vacas leiteiras

Impact of Serum Cytokine Levels on EEG-Measured Arousal Regulation in Patients with Major Depressive Disorder and Healthy Controls

Background: In major depressive disorder (MDD), findings include hyperstable regulation of brain arousal measured by electroencephalography (EEG) vigilance analysis and alterations in serum levels of cytokines. It is also known that cytokines affect sleep-wake regulation. This study investigated the relationship between cytokines and EEG vigilance in participants with MDD and nondepressed controls, and the influence of cytokines on differences in vigilance between the two groups. Methods: In 60 patients with MDD and 129 controls, 15-min resting-state EEG recordings were performed and vigilance was automatically assessed with the VIGALL 2.0 (Vigilance Algorithm Leipzig). Serum levels of the wakefulness-promoting cytokines interleukin (IL)-4, IL-10, IL-13 and somnogenic cytokines tumor necrosis factor-alpha, interferon-gamma and IL-2 were measured prior to the EEG. Results: Summed wakefulness-promoting cytokines, but not somnogenic cytokines, were significantly associated with the time course of EEG vigilance in the MDD group only. In both groups, IL-13 was significantly associated with the course of EEG vigilance. In MDD compared to controls, a hyperstable EEG vigilance regulation was found, significant for group and group x time course interaction. After controlling for wakefulness-promoting cytokines, differences in vigilance regulation between groups remained significant. Conclusions: The present study demonstrated a relationship between wakefulness-promoting cytokines and objectively measured EEG vigilance as an indicator for brain arousal. Altered brain arousal regulation in MDD gives support for future evaluation of vigilance measures as a biomarker in MDD. Since interactions between cytokines and EEG vigilance only moderately differed between the groups and cytokine levels could not explain the group differences in EEG vigilance regulation, cytokines and brain arousal regulation are likely to be associated with MDD in independent ways. (C) 2016 S. Karger AG, Base

Calcium urinary excretion in dairy cows with different levels of glucose tolerance.

O objetivo deste estudo foi avaliar a excreção urinária de Ca durante o periparto em vacas leiteiras com diferentes níveis de tolerância à glicose durante o período de pré-parto

Densidade de semeadura de aveia-preta para máxima produtividade de biomassa.

A população de 300 e 400 pl/m2 apresenta melhor desempenho para oferta precoce de matéria seca. Para produção massa seca acumulada total e a produção de grãos 200 plantas/m² apresentou-se como melhor opção

Incised valley paleoenvironments interpreted by seismic stratigraphic approach in Patos Lagoon, Southern Brazil

<div><p>ABSTRACT: The Rio Grande do Sul (RS) coastal plain area (33,000 km 2 ) had its physiography modified several times through the Quaternary, responding to allogenic and autogenic forcings. The Patos Lagoon covers a significant area of RS coastal plain (10,000 km 2 ), where incised valleys were identified in previous works. About 1,000 km of high resolution (3.5 kHz) seismic profiles, radiocarbon datings, Standard Penetration Test (SPT) and gravity cores were analyzed to interpret the paleoenvironmental evolution as preserved in incised valley infills. Seismic facies were recognized by seismic parameters. The sediment cores were used to ground-truth the seismic interpretations and help in the paleoenvironmental identification. Key surfaces were established to detail the stratigraphical framework, and seismic facies were grouped into four seismic units, which one classified in respective system tracts within three depositional sequences. The oldest preserved deposits are predominantly fluvial and estuarine facies, representing the falling stage and lowstand system tracts. The Holocene transgressive records are dominated by muddy material, mainly represented by estuarine facies with local variations. The transgression culminated in Late Holocene deposits of Patos Lagoon, representing the highstand system tract. The depositional pattern of the vertical succession was controlled by eustatic variations, while the autogenic forcing (paleogeography and sediment supply) modulated the local facies variation.</p></div

Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity

Context Chronic systemic inflammation in obesity originates from local immune responses in visceral adipose tissue. However, assessment of a broad range of inflammation-mediating cytokines and their relationship to physical activity and adipometrics has scarcely been reported to date. Objective To characterize the profile of a broad range of pro-and anti-inflammatory cytokines and the impact of physical activity and energy expenditure in individuals with general obesity, central obesity, and non-obese subjects. Design, Setting, and Participants A cross-sectional study comprising 117 obese patients (body mass index (BMI) >= 30) and 83 non-obese community-based volunteers. Main Outcomes Measures Serum levels of interleukin (IL)-2, IL-4, IL-5, IL-10, IL-12, IL-13, granulocyte-macrophage colony-stimulating factor (GM-CSF),interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha were measured. Physical activity and energy expenditure (MET) were assessed with actigraphy. Adipometrics comprised BMI, weight, abdominal-, waist-and hip-circumference, waist to hip ratio (WHR),and waist-to-height-ratio (WHtR). Results General obesity was associated with significantly elevated levels of IL-5, IL-10, IL-12, IL-13, IFN-gamma and TNF-alpha, central obesity with significantly elevated IL-5, IL-10, IL-12, IL-13 and IFN-gamma-levels. In participants with general obesity, levels of IL-4, IL-10 and IL-13 were significantly elevated in participants with low physical activity, even when controlled for BMI which was negatively associated with physical acitivity. Cytokines significantly correlated with adipometrics, particularly in obese participants. Conclusions Results confirm up-regulation of certain pro-and anti-inflammatory cytokines in obesity. In obese subjects, physical activity may lower levels and thus reduce pro-inflammatory effects of cytokines that may link obesity, insulin resistance and diabetes

Prepartum body condition score changes and the secretion of acute phase proteins in dairy cows.

O objetivo deste estudo foi investigar o efeito da condição corporal (BCS) durante o período de pré-parto, sobre a concentração de proteínas de fase aguda e parâmetros metabólicos em vacas leiteiras

Polos regionais de desenvolvimento do esporte e do lazer: a descentralização da gestão de uma Política de Estado

La implementación del Polo en la UPF es de extrema importancia para el desarrollo regional, permitiendo las políticas públicas de una forma descentralizada y articulada. Se compone de 151 municipios distribuidos en seis micro-regiones correspondientes a las Coordinadoras Regionales de Educación: 7ª, 9ª, 15ª, 20ª, 25ª y 39ª CRE. El polo actúa en sintonía con FUNDERGS como facilitador de acciones, estimulando el desarrollo deportivo en la región e incentivando nuevas alternativas y propuestas volcadas en el deporte y el ocio. En el caso de los municipios de su región, se cuenta con la infraestructura existente en sus dependencias en los diversos eventos propuestos por FUNDERGS y municipios de su región, recibiendo, interpretando, diagnosticando y ayudando a los gestores municipales en sus demandas, siendo el principal interlocutor del Estado. En los dos años de instalación, varias fueron las acciones propuestas por FUNDERGS y desarrolladas por el polo, teniendo públicos y variados objetivos.The implementation of the Pole at UPF is extremely important for regional development, allowing public policies in a decentralized and articulated way. It consists of 151 municipalities distributed in six micro-regions corresponding to the Regional Coordinators of Education: 7th, 9th, 15th, 20th, 25th and 39th CRE. The polo acts in sync with FUNDERGS as a facilitator of actions, stimulating sports development in the region and encouraging new alternatives and proposals focused on sports and leisure. In the case of the municipalities of its region, existing infrastructure in its dependencies is available in the various events proposed by FUNDERGS and municipalities in its region, receiving, interpreting, diagnosing and assisting municipal managers in their demands, the main one being interlocutor of the State. In the two years of installation, several were the actions proposed by FUNDERGS and developed by the pole, having public and varied objectives.A implementação do Polo na UPF é de extrema importância para o desenvolvimento regional, visando as políticas públicas de forma descentralizada e articulada. É composto por 151 municípios distribuídos em 6 micro-regiões correspondente as Coordenadorias Regionais de Educação: 7ª, 9ª, 15ª, 20ª, 25ª e 39ª CRE. O polo atua junto em sintonia com a FUNDERGS como facilitador de ações, estimulando o desenvolvimento esportivo na região e incentivando novas alternativas e propostas voltadas ao esporte e lazer. Disponibiliza a infraestrutura existente nas suas dependências nos diversos eventos propostos pela FUNDERGS, e municípios da sua região, recebendo, interpretando, diagnosticando e auxiliando os gestores municipais em suas demandas, sendo, o principal interlocutor do Estado. Nos dois anos de instalação, várias foram as ações propostas pela FUNDERGS e desenvolvidas pelo polo, tendo público e objetivos variados.peerReviewe