Classification of the Judean Desert Documents (Dead Sea Scrolls)

Wellisch, Hans H

Asymptotic behaviour of estimation equations with functional nuisance or working parameter

We are concerned with the asymptotic theory of semiparametric estimation equations. We are dealing with estimation equations which have a parametric component of interest and a functional (nonparametric) nuisance component. We give sufficient conditions for the existence and the asymptotic normality of a consistent estimation equation estimator for the parameter of interest. These conditions concern the asymptotic distribution of the estimation function and of its derivative as well as the effect of the functional nuisance part in the estimation equation. In order to treat the nonparametric component we introduce a general differential calculus and a general mean value theorem. For the nonparametric part in the estimation equation we distinguish two cases: the situation of a (classical) nuisance parameter and the case of a so called working parameter. As a special case we get regularity conditions for estimation equations with finite dimensional nuisance or working parameter. As an example we present the semiparametric linear regression model

The Geant4 Hadronic Verification Suite for the Cascade Energy Range

A Geant4 hadronic process verification suite has been designed to test and optimize Geant4 hadronic models in the cascade energy range. It focuses on quantities relevant to the LHC radiation environment and spallation source targets. The general structure of the suite is presented, including the user interface, stages of verification, management of experimental data, event generation, and comparison of results to data. Verification results for the newly released Binary cascade and Bertini cascade models are presented.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 5 pages, LaTeX, 3 eps figures. PSN MOMT00

Recent Developments And Validations in Geant4 Hadronic Physics

The Geant4 hadronic models cover the entire range of energies required by calorimeters in new and planned experiments. The extension and improvement of the elastic, cascade, parameterized and quark-gluon string models will be discussed. Such improvements include the extension to more particle types, a review and correction of cross sections, and a better treatment of energy and momentum conservation. Concurrent with this development has been a validation program which includes comparisons with double differential cross sections. An ongoing hadronic shower validation will also be discussed which includes the examination of longitudinal shower shapes and the performance of the above models as well as their interaction with electromagnetic processes such as multiple scattering

Neutral-Current Atmospheric Neutrino Flux Measurement Using Neutrino-Proton Elastic Scattering in Super-Kamiokande

Recent results show that atmospheric $\nu_\mu$ oscillate with $\delta m^2 \simeq 3 \times 10^{-3}$ eV$^2$ and $\sin^2{2\theta_{atm}} \simeq 1$, and that conversion into $\nu_e$ is strongly disfavored. The Super-Kamiokande (SK) collaboration, using a combination of three techniques, reports that their data favor $\nu_\mu \to \nu_\tau$ over $\nu_\mu \to \nu_{sterile}$. This distinction is extremely important for both four-neutrino models and cosmology. We propose that neutrino-proton elastic scattering ($\nu + p \to \nu + p$) in water \v{C}erenkov detectors can also distinguish between active and sterile oscillations. This was not previously recognized as a useful channel since only about 2% of struck protons are above the \v{C}erenkov threshold. Nevertheless, in the present SK data there should be about 40 identifiable events. We show that these events have unique particle identification characteristics, point in the direction of the incoming neutrinos, and correspond to a narrow range of neutrino energies (1-3 GeV, oscillating near the horizon). This channel will be particularly important in Hyper-Kamiokande, with $\sim 40$ times higher rate. Our results have other important applications. First, for a similarly small fraction of atmospheric neutrino quasielastic events, the proton is relativistic. This uniquely selects $\nu_\mu$ (not $\bar{\nu}_\mu$) events, useful for understanding matter effects, and allows determination of the neutrino energy and direction, useful for the $L/E$ dependence of oscillations. Second, using accelerator neutrinos, both elastic and quasielastic events with relativistic protons can be seen in the K2K 1-kton near detector and MiniBooNE.Comment: 10 pages RevTeX, 8 figure

Insomnia and its associations in patients with recurrent glial neoplasms

BACKGROUND: Patient with neurological disorders and cancer can develop sleep disturbance, in particular insomnia. Etiology of insomnia is multi-factorial in primary brain tumour patients with possible causes including corticosteroids, psychoactive medications, co-morbid psychiatric/medical conditions, and damage to neuronal tissue. FINDINGS: To understand better insomnia in recurrent glioma patients, a single-center retrospective analysis was performed looking at recurrent glioma patients from January 2004 to May 2009. Data was extracted and included demographics, clinical factors, psychoactive medications, and co-morbid symptoms. Presence and absence of insomnia complaints was evaluated with other co-morbidities using Chi square and Wilcoxon analyses. Records from 340 recurrent glioma patients were evaluated and 46.8 % (n = 159) indicated presence of insomnia with 20 % (n = 66) actively using medications for sleep. Use of corticosteroids were significantly associated with insomnia (p = 0.0003). Age, gender, tumour location, use of stimulants, antipsychotics, and antidepressants were not significantly associated with insomnia in recurrent glioma patients. There was a trend towards a possible significant association with insomnia to fatigue complaints and use of anti-epileptics, p-values of 0.0501 and 0.0725 respectively. CONCLUSIONS: In conclusion, insomnia is commonly encountered in patients with recurrent glial tumors. Corticosteroid use is associated with insomnia in this population. In light of the frequency of insomnia and its associations, future analysis is warranted into sleep complaints in recurrent glioma patients and its impact on quality of life

GEANT4 : a simulation toolkit

Abstract Geant4 is a toolkit for simulating the passage of particles through matter. It includes a complete range of functionality including tracking, geometry, physics models and hits. The physics processes offered cover a comprehensive range, including electromagnetic, hadronic and optical processes, a large set of long-lived particles, materials and elements, over a wide energy range starting, in some cases, from 250 eV and extending in others to the TeV energy range. It has been designed and constructed to expose the physics models utilised, to handle complex geometries, and to enable its easy adaptation for optimal use in different sets of applications. The toolkit is the result of a worldwide collaboration of physicists and software engineers. It has been created exploiting software engineering and object-oriented technology and implemented in the C++ programming language. It has been used in applications in particle physics, nuclear physics, accelerator design, space engineering and medical physics. PACS: 07.05.Tp; 13; 2