An approach to the cooperation for innovation in the service sector

This study examines how firms cooperate for innovation in the services sector. We tested the theoretical development using cluster analysis and ordinal logit regression analysis with firm-level data collected from the Spanish Technological Innovation Panel (PITEC) for the period 2011-2013. Overall, 2,622 service firms have been used. This research contributes as follows: firstly, the findings show that the greater degree of penetration into the innovation modes of the firms means that the intensity of the use of cooperative agreements as well as the diversity of cooperative partners increases. Secondly, the empirical evidence for the taxonomy of innovation development in the service sector provides firms with the ways how to innovate based on their strategic orientation

Epidemiology and interactions of Human Immunodeficiency Virus - 1 and Schistosoma mansoni in sub-Saharan Africa.

Human Immunodeficiency Virus-1/AIDS and Schistosoma mansoni are widespread in sub-Saharan Africa and co-infection occurs commonly. Since the early 1990s, it has been suggested that the two infections may interact and potentiate the effects of each other within co-infected human hosts. Indeed, S. mansoni infection has been suggested to be a risk factor for HIV transmission and progression in Africa. If so, it would follow that mass deworming could have beneficial effects on HIV-1 transmission dynamics. The epidemiology of HIV in African countries is changing, shifting from urban to rural areas where the prevalence of Schistosoma mansoni is high and public health services are deficient. On the other side, the consequent pathogenesis of HIV-1/S. mansoni co-infection remains unknown. Here we give an account of the epidemiology of HIV-1 and S. mansoni, discuss co-infection and possible biological causal relationships between the two infections, and the potential impact of praziquantel treatment on HIV-1 viral loads, CD4+ counts and CD4+/CD8+ ratio. Our review of the available literature indicates that there is evidence to support the hypothesis that S. mansoni infections can influence the replication of the HIV-1, cell-to-cell transmission, as well as increase HIV progression as measured by reduced CD4+ T lymphocytes counts. If so, then deworming of HIV positive individuals living in endemic areas may impact on HIV-1 viral loads and CD4+ T lymphocyte counts.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

Lawson criterion for ignition exceeded in an inertial fusion experiment

For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37 MJ of fusion for 1.92 MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion

The p-median problem and health facilities: Cost saving and improvement in healthcare delivery through facility location

The importance of health to economic growth and development is an undisputed fact. Modern advancement in technology and healthcare has contributed to improved health and productivity, but there are many people who cannot access healthcare in a timely fashion. Factors affecting delays in accessing healthcare include inadequate supply, poor location, or lack of healthcare facilities all of which can be exacerbated by increasing healthcare costs and scarcity of resources. In this study, we develop a simple two-stage method based on the p-median problem to investigate the location and access to healthcare (emergency) facilities in urban areas. We compare the results of our new method with the results of similar existing methods using 26-node, 42-node, and 55-node data. We also show the efficiency of our method with exact methods using 150-node random data. Our method compares favorably with optimal and the existing methods