GRAFT VERSUS HOST-DISEASE IN THE RAT - IA EXPRESSION ON TARGET TISSUES

Class II (Ia) antigens, in the rat encoded for in the RTlB subregion of the MHC, are potent stimulators of a Graft versus Host Reaction (GvHR) (1). However, the distribution pattern and quantity of Ia antigens expressed on host tissues during a GvHR have not yet been fully established