Cardiovascular profile of vasculitis patients at tertiary care center

Background: The vasculitides are a heterogenous group of conditions characterized by blood vessel inflammation and necrosis. Vasculitides are relatively uncommon conditions whose etiology is still poorly understood. Objective of the research was to study the cardiovascular profile of vasculitis patients at a tertiary care centre.Methods: The present hospital based observational study was conducted in the department of internal medicine, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Jammu and Kashmir, India. The study had two parts: retrospective and prospective. In the retrospective part, all patients of vasculitis who were admitted or evaluated in outpatient department (OPD) from March 2012 to September 2018, were enrolled for the analysis. In the prospective part, all patients of vasculitis admitted or evaluated in OPD from October 2018 to May 2020 were enrolled for study.Results: Out of total 77 patients studied, 39 (50.6%) were prospective cases and 38 (49.4%) cases were of retrospective nature. Normal echocardiographic and electrocardiography (ECG) findings were seen in majority of all three groups. Computed tomography (CT) angio shows involvement of right subclavian artery in 9 (40.9%) patients, 8 (36.4%) patients had involvement of left subclavian artery, 6 (27.3%) patients had involvement of arch of aorta, CT angio was suggestive of involvement left common carotid artery 5 patients, 2 patients each had involvement of celiac artery, bilateral iliac, ascending aorta, normal CT angio findings. Arterial Doppler was suggestive of involvement of right common carotid artery (CCA) and left CCA in 4 (30.8%) patients each, right superior cerebellar artery (SCA) involvement in 3 (23.1%) patients, left SCA involvement in 4 (30.8%) patients, left right brachiocephalic artery (RBA), right RA and B/L UA involvement was observed in 1 (7.7%) patient each.Conclusions: The association between cardiovascular disease and a vasculitis is well documented. our study discusses the association between cv disease and vasculitis

Secondary Tuberculosis of Breast: Case Report

Tuberculosis of breast is a rare disease which is difficult to differentiate from carcinoma of breast. The involvement of breast can be primary or secondary to some focus in body. A case of secondary tuberculosis of right breast in a 21-year-old female from Kashmir, India, is being reported. Presentation was as a painless discharging sinus of right breast. A tubercular foci of rib was the affecting source of disease. No other evidence of tuberculosis was present in the body. Resection of involved rib segment, along with the discharging sinus, was performed. The patient had antitubercular therapy for 9 months, with no recurrence seen in followup

Case Reports: Peritoneal hydatidosis in a young girl

We report a case of peritoneal hydatidosis that occurred post laparotomy. Patient was diagnosed nine months after she had laparotomy for suspected acute appendicitis. The whole peritoneal cavity was studded with cysts. In view of diffuse involvement, patient was managed conservatively and showed response to medical therapy

Genetic diversity and relationship assessment among mulberry (Morus spp) genotypes by simple sequence repeat (SSR) marker profile

Mulberry (Morus L.) is essential for sericulture industry as the primary source of food for silkworm Bombyx mori L. In India, long tradition of practising sericulture includes the use of a large number of indigenous cultivars. Since knowledge on genetic divergence of these cultivars/varieties is imperative for conservation and gainful utilization, simple sequence repeat (SSR) profiling was employed to assess genetic relatedness among 17 mulberry genotypes maintained in the Germplasm Bank of Temperate Sericulture Institute, SKUAST Kashmir, Mirgund. Six SSR primers were utilised which generates 17 alleles among the genotypes. The polymorphism information content (PIC) value varied from 0.260 (MulSTR3) to 0.623 (MulSTR4), with an average of 0.438 per locus. The highest similarity value of 0.92 was observed between Lemoncina and Kanva-2, as compared to the lowest similarity coefficient of 0.15 was between SKM-48 and Chinese white. Clustering of the genotypes was done with unweight pair group method using arithmetic average (UPGMA) which generates five clusters. Cluster-2 contained maximum (six) genotypes.Keywords: Clustering, genetic relatedness, mulberry, SSRAfrican Journal of Biotechnology Vol. 12(21), pp. 3181-318

Studies on Genetic Variability in Dolichos Bean (Lablab purpureus L.)

Fifty seven pole-type vegetable dolichos bean [Lablab purpureus (L.) Sweet] germplasm lines were evaluated for genetic variability, heritability and genetic advance at the experimental farm of Indian Institute of Horticultural Research, Bangalore, during 2010-12. GCV was comparatively high in days to 50% flowering, days to pod maturity, pod length, pod weight, number of pods per cluster, number of pods per plant, pod yield per plant and pod width. High heritability estimates were observed for number of pods per plant, pod yield per plant, pod weight, days to 50% flowering, pod length, days to pod maturity, pod width and number of pods per cluster. High genetic advance, along with relatively high heritability percent, was observed for number of pods per cluster and pod width. Existence of wide variation along with high heritability and genetic advance for number of pods per cluster, pod length, pod width and pod yield per plant indicate that selection would be effective for these traits. Among the accessions studied, IIHR 177 was early for 50% flowering (43 days) and pod maturity (65 days). IIHR 6 and IIHR 11 had maximum pod length (16.5cm) and pod width (4.1cm), respectively. Ten-pod weight was highest in IIHR 7(122g), while the number of pods per plant was high in IIHR 159 (91.0). Maximum pod yield was seen in IIHR 150 (576.9g per plant). These accessions having green, purple or creamy-white pods can be used in future breeding programmes

Quantification of yield gaps in rain-fed rice, wheat, cotton and mustard in India

Rainfed farming / Crop yield / Simulation / Rice / Wheat / Cotton / Mustard / India

Physico-Chemical Characterization Of Sweet Chestnut (Castanea Sativa L.) Starch Grown In Temperate Climate Of Kashmir, India

Studies were conducted to characterize the chestnut starch for physico-chemical properties. Chemical composition of chestnut starch showed low levels of protein and ash indicating purity of starch. The results revealed low water and oil absorption capacity of chestnut starch. Starch showed high swelling power and low solubility index. Swelling power and solubility index of chestnut starch increased with increase in temperature (50–90 °C). The results revealed high initial, peak, setback, breakdown, and final viscosity but low paste development temperature. Transmittance (%) of the starch gel was low and decreased with increasing storage period. The chestnut starch gel showed increase in % water release (syneresis) with increase in time of storage but was less susceptible to repeated cycles of freezing and thawing. Starch was also characterized for granule morphology. Starch granules were of round and oval shapes, some granules showed irregular shape

Garden Pea Improvement in India

Garden pea (Pisum sativum L. var. hortense) is an important legume vegetable grown for its fresh, shelled green seeds rich in proteins, vitamins and minerals. At present over 1000 germplasm lines are available in India. Improvement of garden pea in the country was initiated during the 1940s in IARI and later in several other agricultural universities/ ICAR institutes. Currently, 27 early-varieties and 59 mid-season varieties are under cultivation in india. Initially, focus was on developing early-maturing varieties with high yield and quality. Subsequently, emphasis was laid on developing mid-season varieties having resistance to powdery mildew and other major diseases like Fusarium wilt and rust. Besides, varieties with resistance to bruchids and the leaf miner are also available. In the present paper, an attempt has been made to review current status of improvement of garden pea in India, covering its genetic resources, variability, heritability, genetic advance, heterosis and combining ability, G x E interaction, male sterility, breeding for biotic and abiotic stresses, mutation breeding and biotechnological applications. In recent years, there has been an increase in demand for varieties suited to kharif and early summer seasons, with resistance to powdery mildew, rust, Fusarium root wilt/rot and stemfly and also for processing and export. Therefore, future thrust in the improvement of garden pea would be on developing varieties tolerant to biotic and abiotic stresses (mainly high temperature), and also for processing and export