Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial

BACKGROUND: Hypertension is the number one cardiovascular risk factor in Malaysia. This study aimed to evaluate the effectiveness of a Community-Based Cardiovascular Risk Factors Intervention Strategies (CORFIS) in the management of hypertension in primary care. METHODS: This is a pragmatic, non-randomized controlled trial. Seventy general practitioners (GPs) were selected to provide either CORFIS (44 GPs) or conventional care (26 GPs) for 6 months. A total of 486 hypertensive patients were recruited; 309 were in the intervention and 177 in the control groups. Primary outcome was the proportion of hypertensive patients who achieved target blood pressure (BP) of <140/90mmHg (for those without diabetes mellitus) and <130/80mmHg (with diabetes mellitus). Secondary outcomes include change in the mean/median BP at 6-month as compared to baseline. RESULTS: The proportion of hypertensive patients who achieved target BP at 6-month was significantly higher in the CORFIS arm (69.6) as compared to the control arm (57.6), P=0.008. Amongst those who had uncontrolled BP at baseline, the proportion who achieved target BP at 6-month was also significantly higher in the CORFIS arm (56.6) as compared to the control arm (34.1), p<0.001. There was no difference in the patients who had already achieved BP control at baseline. There were significant reductions in SBP in the CORFIS arm (median -9.0mmHg; -60 to 50) versus control (median -2mmHg; -50 to 48), p=0.003; as well as in DBP (CORFIS arm: median -6.0mmHg; ranged from -53 to 30 versus control arm: median 0.0mmHg; ranged from -42 to 30), p<0.001. CONCLUSIONS: Patients who received CORFIS care demonstrated significant improvements in achieving target BP

Bruch's membrane and its collagen

Available from British Library Document Supply Centre-DSC:DXN012410 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

A brief history of the conchological collections at the Zoological Museum of Amsterdam, with some reflections on 18th century schell cabinets and their proprietors, on the occasion of the centenary of the Royal Zoological Society “Natura Artis Magistra”

At the time when the Royal Zoological Society Natura Artis Magistra known in Holland as “Artis” was founded in 1838 the ground for the study of malacology lay already well prepared. For ever since the days when the early Dutch seafarers explored the commercial routes to East and to West, all kinds of curiosities and natural history objects found their way to the motherland, brought back by the homebound sailors

Research in radiobiology

This report discusses the technical progress made during the past year. Good progress has been made in the areas of bones cells at risk, bone cell morphometry, bone cell residence time, microdistribution of plutonium-239, and the calculation of cell-specific radiation dosimetry. 3 figs., 11 tabs. (KJD

Research in radiobiology. Annual report of work in progress in the internal irradiation program

Separate abstracts were prepared for 13 sections of this report. A list is included of publications during the time period covered by this report

The dependent availability logit model and its application to the intercity travel in Egypt

SIGLEAvailable from British Library Document Supply Centre- DSC:DX175207 / BLDSC - British Library Document Supply CentreGBUnited Kingdo