121 research outputs found

    Search for a State at E_x = 2.6MeV in 20-Na via the 20-Ne(p,n)20-Na Reaction and Possible Breakout from the Hot CNO Cycle

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478

    Fragmentation of High-spin Stretched States in the (p,n) Reaction on 36-Ar and 40-Ca

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478

    Transplacental induction of membranous nephropathy in a neonate

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    We report a case of renal failure in a newborn infant due to membranous glomerulonephritis. The patient was anuric in the first 3 weeks of life, after which renal function recovered. The serum of the mother contained IgG antibodies which reacted with tubular brush borders and glomeruli of adult and fetal human kidneys. Reactivity with renal epithelium from human kidneys was detected. We suggest that a transplacental, passive Heymann nephritis-like mechanism was the pathogenesis of the neonate's symptoms, although the antigen(s) involved was shown not to be gp 330 or any of the renal antigens known to be involved in experimental nephropathies

    High-Spin Stretched States in Nuclei Excited via (p,n) Reactions

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    This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440

    Tissue graft rejection in mice

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    A liver-slice to kidney-bed grafting system was used to study the course of rejection of a specific tissue across various genetic barriers in inbred strains of mice. Rejection or survival, scored histologically at various times after grafting, demonstrated that multiple non H-2 differences cause rejection at least as rapidly as H-2 differences. Differences at the K end of the mouse major histocompatibility complex cause tissue rejection more rapidly than do differences at the D end of the complex. The latter differences cause chronic rejection similar to that found across several minor H locus barriers. The H-2 haplotype carried by the recipient or the strength of the H-2 antigens of the donor affect the survival time in liver tissue grafts. Studies employing this model system will contribute to the definition of different immunogenetic parameters affecting survival of various tissues in a genetically well-defined animal model.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46746/1/251_2005_Article_BF01576941.pd
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