1,099 research outputs found
Cosmological Constant, Gauge Hierarchy and Warped Geometry
It is suggested that the mechanism responsible for the resolution of the
gauge hierarchy problem within the warped geometry framework can be generalized
to provide a new explanation of the extremely tiny vacuum energy density rho_V
suggested by recent observations. We illustrate the mechanism with some 5D
examples in which the true vacuum energy is assumed to vanish, and rho_V is
associated with a false vacuum energy such that rho_V^{1/4} ~ TeV^2/M_{Pl} ~
10^{-3} eV, where M_{Pl} denotes the reduced Planck mass. We also consider a
quintessence-like solution to the dark energy problem.Comment: 10 pages, LaTeX, 2 figures, section on quantum corrections added,
version to appear in Phys. Rev.
On Conformal Infinity and Compactifications of the Minkowski Space
Using the standard Cayley transform and elementary tools it is reiterated
that the conformal compactification of the Minkowski space involves not only
the "cone at infinity" but also the 2-sphere that is at the base of this cone.
We represent this 2-sphere by two additionally marked points on the Penrose
diagram for the compactified Minkowski space. Lacks and omissions in the
existing literature are described, Penrose diagrams are derived for both,
simple compactification and its double covering space, which is discussed in
some detail using both the U(2) approach and the exterior and Clifford algebra
methods. Using the Hodge * operator twistors (i.e. vectors of the
pseudo-Hermitian space H_{2,2}) are realized as spinors (i.e., vectors of a
faithful irreducible representation of the even Clifford algebra) for the
conformal group SO(4,2)/Z_2. Killing vector fields corresponding to the left
action of U(2) on itself are explicitly calculated. Isotropic cones and
corresponding projective quadrics in H_{p,q} are also discussed. Applications
to flat conformal structures, including the normal Cartan connection and
conformal development has been discussed in some detail.Comment: 38 pages, 8 figures, late
In-medium relativistic kinetic theory and nucleon-meson systems
Within the model of coupled nucleon-meson systems, a
generalized relativistic Lenard--Balescu--equation is presented resulting from
a relativistic random phase approximation (RRPA). This provides a systematic
derivation of relativistic transport equations in the frame of nonequilibrium
Green's function technique including medium effects as well as flucuation
effects. It contains all possible processes due to one meson exchange and
special attention is kept to the off--shell character of the particles. As a
new feature of many particle effects, processes are possible which can be
interpreted as particle creation and annihilation due to in-medium one meson
exchange. In-medium cross sections are obtained from the generalized derivation
of collision integrals, which possess complete crossing symmetries.Comment: See nucl-th/9310032 for revised version which the authors
incompetently resubmitted rather than correctly replacing thi
Ultrafast carrier relaxation in GaN, In_(0.05)Ga_(0.95)N and an In_(0.05)Ga_(0.95)/In_(0.15)Ga_(0.85)N Multiple Quantum Well
Room temperature, wavelength non-degenerate ultrafast pump/probe measurements
were performed on GaN and InGaN epilayers and an InGaN multiple quantum well
structure. Carrier relaxation dynamics were investigated as a function of
excitation wavelength and intensity. Spectrally-resolved sub-picosecond
relaxation due to carrier redistribution and QW capture was found to depend
sensitively on the wavelength of pump excitation. Moreover, for pump
intensities above a threshold of 100 microJ/cm2, all samples demonstrated an
additional emission feature arising from stimulated emission (SE). SE is
evidenced as accelerated relaxation (< 10 ps) in the pump-probe data,
fundamentally altering the re-distribution of carriers. Once SE and carrier
redistribution is completed, a slower relaxation of up to 1 ns for GaN and
InGaN epilayers, and 660 ps for the MQW sample, indicates carrier recombination
through spontaneous emission.Comment: submitted to Phys. Rev.
Ionic and electronic structure of sodium clusters up to N=59
We determined the ionic and electronic structure of sodium clusters with even
electron numbers and 2 to 59 atoms in axially averaged and three-dimensional
density functional calculations. A local, phenomenological pseudopotential that
reproduces important bulk and atomic properties and facilitates structure
calculations has been developed. Photoabsorption spectra have been calculated
for , , and to
. The consistent inclusion of ionic structure considerably
improves agreement with experiment. An icosahedral growth pattern is observed
for to . This finding is supported by
photoabsorption data.Comment: To appear in Phys. Rev. B 62. Version with figures in better quality
can be requested from the author
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness
BACKGROUND:
There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU).
METHODS:
In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. The volume and dose of a trial drug or placebo was halved or doubled at 12-hour intervals on the basis of the presence or absence of delirium, as detected with the use of the Confusion Assessment Method for the ICU, and of side effects of the intervention. The primary end point was the number of days alive without delirium or coma during the 14-day intervention period. Secondary end points included 30-day and 90-day survival, time to freedom from mechanical ventilation, and time to ICU and hospital discharge. Safety end points included extrapyramidal symptoms and excessive sedation.
RESULTS:
Written informed consent was obtained from 1183 patients or their authorized representatives. Delirium developed in 566 patients (48%), of whom 89% had hypoactive delirium and 11% had hyperactive delirium. Of the 566 patients, 184 were randomly assigned to receive placebo, 192 to receive haloperidol, and 190 to receive ziprasidone. The median duration of exposure to a trial drug or placebo was 4 days (interquartile range, 3 to 7). The median number of days alive without delirium or coma was 8.5 (95% confidence interval [CI], 5.6 to 9.9) in the placebo group, 7.9 (95% CI, 4.4 to 9.6) in the haloperidol group, and 8.7 (95% CI, 5.9 to 10.0) in the ziprasidone group (P=0.26 for overall effect across trial groups). The use of haloperidol or ziprasidone, as compared with placebo, had no significant effect on the primary end point (odds ratios, 0.88 [95% CI, 0.64 to 1.21] and 1.04 [95% CI, 0.73 to 1.48], respectively). There were no significant between-group differences with respect to the secondary end points or the frequency of extrapyramidal symptoms.
CONCLUSIONS:
The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium. (Funded by the National Institutes of Health and the VA Geriatric Research Education and Clinical Center; MIND-USA ClinicalTrials.gov number, NCT01211522 .)
Brane gravity, higher derivative terms and non-locality
In brane world scenarios with a bulk scalar field between two branes it is
known that 4-dimensional Einstein gravity is restored at low energies on either
brane. By using a gauge-invariant gravitational and scalar perturbation
formalism we extend the theory of weak gravity in the brane world scenarios to
higher energies, or shorter distances. We argue that weak gravity on either
brane is indistinguishable from 4-dimensional higher derivative gravity,
provided that the inter-brane distance (radion) is stabilized, that the
background bulk scalar field is changing near the branes and that the
background bulk geometry near the branes is warped. This argument holds for a
general conformal transformation to a frame in which matter on the branes is
minimally coupled to the metric. In particular, Newton's constant and the
coefficients of curvature-squared terms in the 4-dimensional effective action
are determined up to an ambiguity of adding a Gauss-Bonnet topological term. In
other words, we provide the brane-world realization of the so called
-model without utilizing a quantum theory. We discuss the appearance of
composite spin-2 and spin-0 fields in addition to the graviton on the brane and
point out a possibility that the spin-0 field may play the role of an effective
inflaton to drive brane-world inflation. Finally, we conjecture that the
sequence of higher derivative terms is an infinite series and, thus, indicates
non-locality in the brane world scenarios.Comment: Latex, 18 pages; a comment on the spurious tensor mode was added;
recovery condition of higher derivative gravity clarifie
Equidistribution of zeros of holomorphic sections in the non compact setting
We consider N-tensor powers of a positive Hermitian line bundle L over a
non-compact complex manifold X. In the compact case, B. Shiffman and S.
Zelditch proved that the zeros of random sections become asymptotically
uniformly distributed with respect to the natural measure coming from the
curvature of L, as N tends to infinity. Under certain boundedness assumptions
on the curvature of the canonical line bundle of X and on the Chern form of L
we prove a non-compact version of this result. We give various applications,
including the limiting distribution of zeros of cusp forms with respect to the
principal congruence subgroups of SL2(Z) and to the hyperbolic measure, the
higher dimensional case of arithmetic quotients and the case of orthogonal
polynomials with weights at infinity. We also give estimates for the speed of
convergence of the currents of integration on the zero-divisors.Comment: 25 pages; v.2 is a final update to agree with the published pape
Evaluation of the modified FINDRISC to identify individuals at high risk for diabetes among middle-aged white and black ARIC study participants
Objective: To evaluate a modified Finnish Diabetes Risk Score (FINDRISC) for predicting the risk of incident diabetes among white and black middle-aged participants from the Atherosclerosis Risk in Communities (ARIC) study. Research design and methods: We assessed 9754 ARIC cohort participants who were free of diabetes at baseline. Logistic regression and receiver operator characteristic (ROC) curves were used to evaluate a modified FINDRISC for predicting incident diabetes after 9 years of follow-up, overall and by race/gender group. The modified FINDRISC used comprised age, body mass index, waist circumference, blood pressure medication and family history. Results: The mean FINDRISC (range, 2 [lowest risk] to 17 [highest risk]) for black women was higher (9.9 ± 3.6) than that for black men (7.6 ± 3.9), white women (8.0 ± 3.6) and white men (7.6 ± 3.5). The incidence of diabetes increased generally across deciles of FINDRISC for all 4 race/gender groups. ROC curve statistics for the FINDRISC showed the highest area under the curve for white women (0.77) and the lowest for black men (0.70). Conclusions: We used a modified FINDRISC to predict the 9-year risk of incident diabetes in a biracial US population. The modified risk score can be useful for early screening of incident diabetes in biracial populations, which may be helpful for early interventions to delay or prevent diabetes
First results of the air shower experiment KASCADE
The main goals of the KASCADE (KArlsruhe Shower Core and Array DEtector)
experiment are the determination of the energy spectrum and elemental
composition of the charged cosmic rays in the energy range around the knee at
ca. 5 PeV. Due to the large number of measured observables per single shower a
variety of different approaches are applied to the data, preferably on an
event-by-event basis. First results are presented and the influence of the
high-energy interaction models underlying the analyses is discussed.Comment: 3 pages, 3 figures included, to appear in the TAUP 99 Proceedings,
Nucl. Phys. B (Proc. Suppl.), ed. by M. Froissart, J. Dumarchez and D.
Vignau
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