Across-sectional study on the prevalence of Thai adolescent depression

This large-scale study aimed to investigate the prevalence of depression in 4,089 Thai adolescents of both sexes. The participants were between 11 and 16 years old and sampled from all the various regions of Thailand to be representative of the entire country. The Thai translation of the Patient Health Questionnaire for Adolescents (PHQ-A) was employed to collect data. Descriptive statistics and chi-square tests of independence were used for data analysis. The results revealed that the vast majority of the participants (72.2%) had either a mild (44.5%; PHQ-A = 5–9) or at least a moderate form of depression (27.7 %; PHQ-A ≥ 10). Further analysis found that females (χ2 = 41.9, p =.000), poor academic results (χ2 = 12.7, p = .013), low family income (χ2 = 18.0, p =.021), suicidal thoughts (χ2 = 811.0, p =.000) and suicide attempts (χ2 = 414.4, p =.000) were associated with depression, while age (χ2 = 8.9, p = .064) was not associated with depression. Compared to worldwide PHQ-A-based studies of adolescent depression, it would appear that the prevalence of depression in Thai adolescents is common and relatively high

A global experience-sampling method study of well-being during times of crisis : The CoCo project

We present a global experience-sampling method (ESM) study aimed at describing, predicting, and understanding individual differences in well-being during times of crisis such as the COVID-19 pandemic. This international ESM study is a collaborative effort of over 60 interdisciplinary researchers from around the world in the “Coping with Corona” (CoCo) project. The study comprises trait-, state-, and daily-level data of 7490 participants from over 20 countries (total ESM measurements = 207,263; total daily measurements = 73,295) collected between October 2021 and August 2022. We provide a brief overview of the theoretical background and aims of the study, present the applied methods (including a description of the study design, data collection procedures, data cleaning, and final sample), and discuss exemplary research questions to which these data can be applied. We end by inviting collaborations on the CoCo dataset

Effects of Lasia spinosa Thw. on growth rate and reproductive hormone of weaned Swamp buffalo and Murrah X Swamp buffalo calves

The effects of Lasia spinosa Thw. on growth rate and plasma Oestradiol 17- β (E2), Progesterone (P4) and Testosterone (T) were studied in 16 male and female swamp (SS) buffaloes and Murrah x Swamp buffalo crossbreeds (MS) calves. The treatment group was fed with a concentrate supplemented with 30 g of dry powder of L. spinosa/head/d for 7 months. It was found that L .spinosa could have effect on male and female buffalo growth rate. The growth rate of male SS treated group were 130 g/d higher than control group. In female both SS and MS buffalo, the highest growth rate (830 to 840 g/d) was found after the 2nd month of treatment while a reduction in growth rate (-1,030 to - 450 g/d) was found in the 3rd month. After that the growth rate of SS and MS gradually increased until the last three months to 200 and 80 g/d in average, respectively. In female MS, plasma E2 in the treated group was lower than control group during Jan to Jul. Similar result was found in SS female, level of plasma E2 in treated group was lower than in control group in the first and last three month and there was no difference of plasma E2 in May. In MS male, the level of plasma E2 of treated group was higher than control group in Jan, Mar, Apr and Jul. In SS male, the level of plasma E2 of treated group was higher than control group in every month except in Jul. In female SS, L. spinosa could decreased plasma P4 through the experiment and could not have an effect on plasma P4 in female MS and plasma T in male buffalo calves. In conclusion, the addition to the concentrate of dry powder of L. spinosa 30 g/headl/d had an effect to increase growth rate in male SS and female MS buffalo calves, decrease plasma E2 in female both SS and MS and male SS and decrease plasma P4 in female SS

Transient hypoxia in water irradiated by swift carbon ions at ultra-high dose rates: implication for FLASH carbon-ion therapy

Large doses of ionizing radiation delivered to tumors at ultra-high dose rates (i.e., in a few milliseconds) paradoxically spare the surrounding healthy tissue while preserving anti-tumor activity (compared to conventional radiotherapy delivered at much lower dose rates). This new modality is known as “FLASH radiotherapy” (FLASH-RT). Although the molecular mechanisms underlying FLASH-RT are not yet fully understood, it has been suggested that radiation delivered at high dose rates spares normal tissue via oxygen depletion followed by subsequent radioresistance of the irradiated tissue. To date, FLASH-RT has been studied using electrons, photons and protons in various basic biological experiments, pre-clinical studies, and recently in a human patient. However, the efficacy of heavy ions, such as swift carbon ions, under FLASH conditions remains unclear. Given that living cells and tissues consist mainly of water, we set out to study, from a pure radiation chemistry perspective, the effects of ultra-high dose rates on the transient yields and concentrations of radiolytic species formed in water irradiated by 300-MeV per nucleon carbon ions (LET ~ 11.6 keV/μm). This mimics irradiation in the “plateau” region of the depth-dose distribution of ions, i.e., in the “normal” tissue region in which the LET is rather low. We used Monte Carlo simulations of multiple, simultaneously interacting radiation tracks together with an “instantaneous pulse” irradiation model. Our calculations show a pronounced oxygen depletion around 0.2 μs, strongly suggesting, as with electrons, photons and protons, that irradiation with energetic carbon ions at ultra-high dose rates is suitable for FLASH-RT.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

A global experience‐sampling method study of well‐being during times of crisis: The CoCo project

We present a global experience-sampling method (ESM) study aimed at describing, predicting, and understanding individual differences in well-being during times of crisis such as the COVID-19 pandemic. This international ESM study is a collaborative effort of over 60 interdisciplinary researchers from around the world in the “Coping with Corona” (CoCo) project. The study comprises trait-, state-, and daily-level data of 7490 participants from over 20 countries (total ESM measurements = 207,263; total daily measurements = 73,295) collected between October 2021 and August 2022. We provide a brief overview of the theoretical background and aims of the study, present the applied methods (including a description of the study design, data collection procedures, data cleaning, and final sample), and discuss exemplary research questions to which these data can be applied. We end by inviting collaborations on the CoCo dataset