47 research outputs found

    Short-term outcome after posterior versus lateral surgical approach for total hip arthroplasty - a randomized clinical trial*

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    <p>Abstract</p> <p>Purpose</p> <p>Currently, total hip replacement (THR) is most commonly performed via a posterior or a direct lateral approach, but the impact of the latter on the invention's outcome has yet not been quantified.</p> <p>Methods</p> <p>We compared the short-term outcome of cementless THR using the both approaches in a prospective, randomized controlled trial. 60 patients with unilateral osteoarthritis were included. Outcome assessment was performed one day before surgery and one week, four weeks, six weeks and 12 weeks after surgery, respectively, using the Harris Hip score as primary objective.</p> <p>Results</p> <p>We found no significant difference in the intraindividual Harris Hip Score improvement at the pre-and three months post-operative assessments between both treatment groups (p = 0.115). However, Harris Hip scores and most functional and psychometric secondary endpoints showed a consistent tendency of a slightly better three months result in patients implanted via the posterior approach. In contrast a significant shorter operating time of the direct lateral approach was recorded (67 minutes versus 76 minutes, p < 0.001).</p> <p>Conclusion</p> <p>In our opinion this slightly better short-term functional outcome after posterior approach is not clinical relevant. However, to make definitive conclusions all clinical relevant factors (i.e. mid- to long-term function, satisfaction, complication rates and long-term survival) have to be taken into account. <it>Level of evidence: </it>I - therapeutic</p

    Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

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