9,472 research outputs found

    Quantum Computers, Factoring, and Decoherence

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    In a quantum computer any superposition of inputs evolves unitarily into the corresponding superposition of outputs. It has been recently demonstrated that such computers can dramatically speed up the task of finding factors of large numbers -- a problem of great practical significance because of its cryptographic applications. Instead of the nearly exponential (expL1/3\sim \exp L^{1/3}, for a number with LL digits) time required by the fastest classical algorithm, the quantum algorithm gives factors in a time polynomial in LL (L2\sim L^2). This enormous speed-up is possible in principle because quantum computation can simultaneously follow all of the paths corresponding to the distinct classical inputs, obtaining the solution as a result of coherent quantum interference between the alternatives. Hence, a quantum computer is sophisticated interference device, and it is essential for its quantum state to remain coherent in the course of the operation. In this report we investigate the effect of decoherence on the quantum factorization algorithm and establish an upper bound on a ``quantum factorizable'' LL based on the decoherence suffered per operational step.Comment: 7 pages,LaTex + 2 postcript figures in a uuencoded fil

    Cocommutative coalgebras: homotopy theory and Koszul duality

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    We extend a construction of Hinich to obtain a closed model category structure on all differential graded cocommutative coalgebras over an algebraically closed field of characteristic zero. We further show that the Koszul duality between commutative and Lie algebras extends to a Quillen equivalence between cocommutative coalgebras and formal coproducts of curved Lie algebras.Comment: 38 page

    Research on digital transducer principles. Volume 7 - Dielectric properties of thin polymer films, 1 July 1967 - 30 June 1968

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    Dielectric properties of thin films of polymerized oil-metal-silicon structure

    Deutsch-Jozsa algorithm as a test of quantum computation

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    A redundancy in the existing Deutsch-Jozsa quantum algorithm is removed and a refined algorithm, which reduces the size of the register and simplifies the function evaluation, is proposed. The refined version allows a simpler analysis of the use of entanglement between the qubits in the algorithm and provides criteria for deciding when the Deutsch-Jozsa algorithm constitutes a meaningful test of quantum computation.Comment: 10 pages, 2 figures, RevTex, Approved for publication in Phys Rev

    Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.

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    Activation of Hedgehog (Hh) signaling requires the transmembrane protein Smoothened (Smo), a member of the G-protein coupled receptor superfamily. In mammals, Smo translocates to the primary cilium upon binding of Hh ligands to their receptor, Patched (Ptch1), but it is unclear if ciliary trafficking of Smo is sufficient for pathway activation. Here, we demonstrate that cyclopamine and jervine, two structurally related inhibitors of Smo, force ciliary translocation of Smo. Treatment with SANT-1, an unrelated Smo antagonist, abrogates cyclopamine- and jervine-mediated Smo translocation. Further, activation of protein kinase A, either directly or through activation of Galphas, causes Smo to translocate to a proximal region of the primary cilium. We propose that Smo adopts multiple inactive and active conformations, which influence its localization and trafficking on the primary cilium
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