34,494 research outputs found

    Current Dissipation in Thin Superconducting Wires: Accurate Numerical Evaluation Using the String Method

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    Current dissipation in thin superconducting wires is numerically evaluated by using the string method, within the framework of time-dependent Ginzburg-Landau equation with a Langevin noise term. The most probable transition pathway between two neighboring current-carrying metastable states, continuously linking the Langer-Ambegaokar saddle-point state to a state in which the order parameter vanishes somewhere, is found numerically. We also give a numerically accurate algorithm to evaluate the prefactors for the rate of current-reducing transitions.Comment: 25 pages, 5 figure

    A Novel Alcohol-Sensitive Site in the M3 Domain of the NMDA Receptor GluN2A Subunit

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    Accumulating studies have demonstrated that the N-methyl-D-aspartate receptor is one of the most important targets of ethanol in the central nervous system. Previous studies from this laboratory have found that one position in the third (F637) and two positions in the fourth (M823 and A825) membrane-associated (M) domains of the N-methyl-D-aspartate receptor GluN2A subunit modulate alcohol action and ion channel gating. Using site-directed mutagenesis and whole-cell patch-clamp recording, we have found an additional position in M3 of the GluN2A subunit, F636, which significantly influences ethanol sensitivity and functionally interacts with F637. Tryptophan substitution at F636 significantly decreased the ethanol IC50, decreased both peak and steady-state glutamate EC50, and altered agonist deactivation and apparent desensitization. There was a significant correlation between steadystate: peak current ratio, a measure of desensitization, and ethanol IC50 values for a series of mutants at this site, raising the possibility that changes in ethanol sensitivity may be secondary to changes in desensitization. Mutant cycle analysis revealed a significant interaction between F636 and F637 in regulating ethanol sensitivity. Our results suggest that F636 in the M3 domain of the GluN2A subunit not only influences channel gating and agonist potency, but also plays an important role in mediating the action of ethanol. These studies were supported by grants R01 AA015203-01A1 and AA015203-06A1 from the NIAAA to R.W.P

    Qualitative picture of a new mechanism for high-Tc superconductors

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    Xu et al. observed enhanced Nernst effect and Iguchi et al. observed patched diamagnetism, both well above TcT_c in underdoped high-TcT_c superconductors (HTSCs). A new mechanism is proposed here, which seems to naturally explain, at least qualitatively, these observations, as well as the d-wave nature and continuity of pseudogap and pairing gap, the tunneling conductance above TcT_c, as well as T∗(x)T^*(x), Tν(x)T_{\nu}(x), Tc(x)T_c(x), etc. This mechanism combines features of dynamic charged stripes, preformed pairs, and spin-bags: At appropriete doping levels, the doped holes (and perhaps also electrons) will promote the formation of anti-phase islands in short-range anti-ferromagnetic order. On the boundary of each such island reside two doped carriers; the unscreened Coulomb repulsion between them stabilizes its size. Superconductivity results when such ``pre-formed pairs'' Bose-condense.Comment: 8 pages, 4 figures, New3SC-4 Conference Proceedings, to be published in ijmp

    Gender Differentials in the Payoff to Schooling in China

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    This paper examines the gender differential in the payoff to schooling in China. The analyses are conducted separately for rural and urban areas, and are based on a framework provided by the over education/required education/under education literature, and the decomposition developed by Chiswick and Miller (2008). It shows that the payoff to correctly matched education in rural China is much higher for females than for males. Associated with this, the wage penalty where workers are under qualified in their occupation is greater for females than for males. Both of these factors are shown to be linked to the higher payoff to schooling for females than for males. Over educated females, however, are advantaged compared with their male counterparts, though this has little effect on the differential in the payoff to schooling between males and females in rural China. These findings are interpreted using the explanations offered for the gender differential in the payoff to schooling in the growing literature on earnings determination in China. The payoffs to actual years of schooling for males and females in urban China are remarkably similar in this study.schooling, earnings, rates of return, China

    Large enhancement of the effective second-order nonlinearity in graphene metasurfaces

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    Using a powerful homogenization technique, one- and two-dimensional graphene metasurfaces are homogenized both at the fundamental frequency (FF) and second harmonic (SH). In both cases, there is excellent agreement between the predictions of the homogenization method and those based on rigorous numerical solutions of Maxwell equations. The homogenization technique is then employed to demonstrate that, owing to a double-resonant plasmon excitation mechanism that leads to strong, simultaneous field enhancement at the FF and SH, the effective second-order susceptibility of graphene metasurfaces can be enhanced by more than three orders of magnitude as compared to the intrinsic second-order susceptibility of a graphene sheet placed on the same substrate. In addition, we explore the implications of our results on the development of new active nanodevices that incorporate nanopatterned graphene structures.Comment: 11 pages, 12 figure
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