41 research outputs found
Business angels in the Czech Republic: characteristics and a classification with policy implications
Informal Investments in Transition: The Motivations, Characteristics and Classification of Informal Investors in Croatia, Hungary and Slovenia
Business angels and love money investors: segments of the informal market for risk capital
Transcatheter aortic valve replacement in Europe: adoption trends and factors influencing device utilization
OBJECTIVES
The authors sought to examine the adoption of transcatheter aortic valve replacement (TAVR) in Western Europe and investigate factors that may influence the heterogeneous use of this therapy.
BACKGROUND
Since its commercialization in 2007, the number of TAVR procedures has grown exponentially.
METHODS
The adoption of TAVR was investigated in 11 European countries: Germany, France, Italy, United Kingdom, Spain, the Netherlands, Switzerland, Belgium, Portugal, Denmark, and Ireland. Data were collected from 2 sources: 1) lead physicians submitted nation-specific registry data; and 2) an implantation-based TAVR market tracker. Economic indexes such as healthcare expenditure per capita, sources of healthcare funding, and reimbursement strategies were correlated to TAVR use. Furthermore, we assessed the extent to which TAVR has penetrated its potential patient population.
RESULTS
Between 2007 and 2011, 34,317 patients underwent TAVR. Considerable variation in TAVR use existed across nations. In 2011, the number of TAVR implants per million individuals ranged from 6.1 in Portugal to 88.7 in Germany (33 ± 25). The annual number of TAVR implants performed per center across nations also varied widely (range 10 to 89). The weighted average TAVR penetration rate was low: 17.9%. Significant correlation was found between TAVR use and healthcare spending per capita (r = 0.80; p = 0.005). TAVR-specific reimbursement systems were associated with higher TAVR use than restricted systems (698 ± 232 vs. 213 ± 112 implants/million individuals ≥ 75 years; p = 0.002).
CONCLUSIONS
The authors' findings indicate that TAVR is underutilized in high and prohibitive surgical risk patients with severe aortic stenosis. National economic indexes and reimbursement strategies are closely linked with TAVR use and help explain the inequitable adoption of this therapy
Diana: a symbol of women entrepreneurs’ hunt for knowledge, money, and the rewards of entrepreneurship
Equity funding, Female entrepreneurship, Growth resources, Venture capital, L26,