5,164 research outputs found
Long-term results in pancreatic transplantation with special emphasis on the use of prolamine
Our pancreatic transplantation programme was initiated in 1979. Since then a total of 102 pancreas transplantations have been performed, blocking exocrine secretion using the duct occlusion technique with prolamine. Early non-immunological complications are frequent. The long-term results (9 years) in combined pancreas and kidney transplanted patients are satisfying: the survival rate for pancreas is 38% and 54% for kidney. Patient survival rate in this period is 85%. Beyond the first year post-transplant the exocrine activity disappears whereas the endocrine function remains well preserved
An investigation into a possible relationship between metals and death loss in dolphins
http://www.worldcat.org/oclc/2189021
Aspects of the Mass Distribution of Interstellar Dust Grains in the Solar System from In-Situ Measurements
The in-situ detection of interstellar dust grains in the Solar System by the
dust instruments on-board the Ulysses and Galileo spacecraft as well as the
recent measurements of hyperbolic radar meteors give information on the
properties of the interstellar solid particle population in the solar vicinity.
Especially the distribution of grain masses is indicative of growth and
destruction mechanisms that govern the grain evolution in the interstellar
medium. The mass of an impacting dust grain is derived from its impact velocity
and the amount of plasma generated by the impact. Because the initial velocity
and the dynamics of interstellar particles in the Solar System are well known,
we use an approximated theoretical instead of the measured impact velocity to
derive the mass of interstellar grains from the Ulysses and Galileo in-situ
data. The revised mass distributions are steeper and thus contain less large
grains than the ones that use measured impact velocities, but large grains
still contribute significantly to the overall mass of the detected grains. The
flux of interstellar grains with masses is determined to
be . The comparison of radar data
with the extrapolation of the Ulysses and Galileo mass distribution indicates
that the very large () hyperbolic meteoroids detected by
the radar are not kinematically related to the interstellar dust population
detected by the spacecraft.Comment: 14 pages, 11 figures, to appear in JG
Follow-up study of sensory-motor polyneuropathy in Type 1 (insulin-dependent) diabetic subjects after simultaneous pancreas and kidney transplantation and after graft rejection
The influence of successful simultaneous pancreas and kidney transplantation on peripheral polyneuropathy was investigated in 53 patients for a mean observation period of 40.3 months. Seventeen patients were followed-up for more than 3 years. Symptoms and signs were assessed every 6 months using a standard questionnaire, neurological examination and measurement of sensory and motor nerve conduction velocities. While symptoms of polyneuropathy improved (pain, paraesthesia, cramps, restless-legs) and nerve conduction velocity increased, there was no change of clinical signs (sensation, muscle-force, tendon-reflexes). Following kidney-graft-rejection there was a slight decrease of nerve conduction verlocity during the first year, which was not statistically significant. Following pancreas-graft rejection there was no change of nerve conduction velocity during the first year. Comparing the maximum nerve conduction velocity of the patients with pancreas-graft-rejection to the nerve conduction velocities of these patients at the end of the study, there was a statistically significant decrease of 6.5 m/s.
In conclusion, we believe that strict normalization of glucose metabolism alters the progressive course of diabetic polyneuropathy. It may be stabilized or partly reversed after successful grafting even in long-term diabetic patients
High Rate Performance of Drift Tubes
This article describes calculations and measurements of space charge effects
due to high rate irradiation in high resolution drift tubes. Two main items are
studied: the reduction of the gas gain and changes of the drift time. Whereas
the gain reduction is similar for all gases and unavoidable, the drift time
changes depend on the kind of gas that is used. The loss in resolution due to
high particle rate can be minimized with a suitable gas. This behaviour is
calculable, allowing predictions for new gas mixtures.Comment: 20 pages, submitted to Nuclear Instruments and Methods
Outcome of renal grafts after simultaneous kidney/ pancreas transplantation
Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique. Another group of 25 Type 1 diabetic patients received pancreas/kidney transplants by the duct occlusion technique. We observed a higher incidence of rejection episodes in the patients of the bladder drainage group than those in the duct occlusion group, 14 of 19 patients (74%) vs 7 of 25 (28%) respectively. Anti CD3 antibodies (Orthoclone, OKT3) as a part of induction treatment was used more often in the bladder drainage group (58%) than in the control group (20%)
Modifizierte Operationstechnik und postoperatives Management nach simultaner Pankreas- und Nierentransplantation
PDB22 New Meta-Analysis of Patient-Level Data on Efficacy And Hypoglycaemia with Insulin Glargine or Nph Insulin in Type 2 Diabetes Mellitus (T2DM) According to Concomitant Oral Therapy
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