Misuse Of Public Interest Litigation: A Critical Study As How It Is A Major Threat To Judiciary

Regardless of how much advancement PILs have brought to the Indian Judicial framework, we can't unseen the other side of the coin at any expense as PILs are being mishandled a great deal these days alongside its broad and manhandled use. They have brought different traps and downsides as well. Thusly, to keep away from such instances of maltreatment of the PILs, the high court itself set out a definite rule that will be utilized to administer the administration and removal of the PILs. Numerous PIL activists in India have been utilizing the PILs as a helpful apparatus for pestering the legal framework. Since recording PILs is a modest cycle, numerous unimportant cases are being documented with no speculation of heavy court charges which one would typically pay for common prosecution cases. Subsequently, by recording such cases, bargains are haggled to get cash for the said bothered party to get the PILs. The basic clarification for such cases is that any weapon that can be utilized to safeguard oneself can likewise be utilized to assault somebody. Utilizing a similar rationale, one can bring down the Locus Standi prerequisites which license the inspired gatherings to record PILs which could address a public interest matter

ChemTextMiner: An open source tool kit for mining medical literature abstracts

Text mining involves recognizing patterns from a wealth of information hidden latent in unstructured text and deducing explicit relationships among data entities by using data mining tools. Text mining of Biomedical literature is essential for building biological network connecting genes, proteins, drugs, therapeutic categories, side effects etc. related to diseases of interest. We present an approach for textmining biomedical literature mostly in terms of not so obvious hidden relationships and build biological network applied for the textmining of important human diseases like MTB, Malaria, Alzheimer and Diabetes. The methods, tools and data used for building biological networks using a distributed computing environment previously used for ChemXtreme[1] and ChemStar[2] applications are also described

Virosome: A vector in vaccine delivery

These days vaccines are considered the best economical and effective technique for preventing and handling bacterial infections, like human papillomavirus (HPV) or meningitis, allergies, autoimmune Relevant Disorders, Microbial Infections, and many more viral diseases. Annually millions of lives are saved from death-causing infections and other relevant disorders with the help of proper immunization with the help of vaccines. But still, many diseases are not yet preventable by vaccines and there is a chance of the improvement of current vaccines with help of many approaches. One of these is a compound known as a virosome, which is produced when pure haemagglutinin and neuraminidase projections of the influenza virus surface are removed from viral envelope and deposited on the exterior of unilamellar liposomes.Studies have shown that in order to attain the desired therapeutic effect, a physical attachment between the target antigen and the virosomal carrier is necessary. A virosome can bind to and “infect” host cells and deliver the antigen directly into the processing pathway which is an Alternatively, the virosome may be phagocytosed by an APC. So Our review gives a novel idea of the vector technology for vaccine delivery, its properties, method of preparation, and importance as well as some applications of different virosomal vaccine discoveries

Mitochondrial Pharmacotherapeutics - Advancements and Applications

Mitochondria, known as the “powerhouse of the cell”, plays an important role in the occurrence of multiple diseases and disorders. Mitochondria are believed to come into existence from the synergistic relationship between the proto-eukaryotic and primitive prokaryotic efficient by oxidative phosphorylation. It is the major hub of Adenosine Tri Phosphate production through the implementation of oxidative phosphorylation. It is the processing unit of the “Electron transport chain”. Mitochondria is useful in dealing with various cancers, cardiovascular problems, fatty-acid oxidation disorders, and several kinds of tumours and also several cancers

Achieving a cure for HIV infection: do we have reasons to be optimistic?

The introduction of highly active antiretroviral therapy (HAART) in 1996 has transformed a lethal disease to a chronic pathology with a dramatic decrease in mortality and morbidity of AIDS-related symptoms in infected patients. However, HAART has not allowed the cure of HIV infection, the main obstacle to HIV eradication being the existence of quiescent reservoirs. Several other problems have been encountered with HAART (such as side effects, adherence to medication, emergence of resistance and cost of treatment), and these motivate the search for new ways to treat these patients. Recent advances hold promise for the ultimate cure of HIV infection, which is the topic of this review. Besides these new strategies aiming to eliminate the virus, efforts must be made to improve current HAART. We believe that the cure of HIV infection will not be attained in the short term and that a strategy based on purging the reservoirs has to be associated with an aggressive HAART strategy

Not Available

Not AvailableLymphadenitis cases in a dromedary camel herd located at Bikaner, Rajasthan, India is reported. Enlargement and suppuration of one or more peripheral lymph nodes including parotid, maxillary, prescapular, inferior cervical and popleteal lymph nodes were observed. The overall morbidity rate was 11.37%. Morbidity rate was highest in female and male animals in the age group of 6 years and above. The male and female animals below 2 years of age were least affected. The genomic DNA extracted from pure bacterial culture was sequenced and the NCBI blast analysis of the 16s rDNA sequences revealed 98 per cent homology with C. pseudotuberculosis. In vitro antimicrobial sensitivity testing revealed that the isolate was sensitive to many antibacterial agents but resistant to cloxacillin. The surgical drainage of pus and parenteral therapy with enrofloxacin resulted into clinical recovery.Not Availabl

Mitochondrial Pharmacotherapeutics - Advancements and Applications

Mitochondria, known as the “powerhouse of the cell”, plays an important role in the occurrence of multiple diseases and disorders. Mitochondria are believed to come into existence from the synergistic relationship between the proto-eukaryotic and primitive prokaryotic efficient by oxidative phosphorylation. It is the major hub of Adenosine Tri Phosphate production through the implementation of oxidative phosphorylation. It is the processing unit of the “Electron transport chain”. Mitochondria is useful in dealing with various cancers, cardiovascular problems, fatty-acid oxidation disorders, and several kinds of tumours and also several cancers

Not Available

Not AvailableLymphadenitis cases in a dromedary camel herd located at Bikaner, Rajasthan, India is reported. Enlargement and suppuration of one or more peripheral lymph nodes including parotid, maxillary, prescapular, inferior cervical and popleteal lymph nodes were observed. The overall morbidity rate was 11.37 per cent. Morbidity rate was highest in female and male animals in the age group of 6 years and above. The male and female animals below 2 years of age were least affected. The genomic DNA extracted from pure bacterial culture was sequenced and the NCBI blast analysis of the 16s rDNA sequences revealed 98 per cent homology with C. pseudotuberculosis. In vitro antimicrobial sensitivity testing revealed that the isolate was sensitive to many antibacterial agents but resistant to cloxacillin. The surgical drainage of pus and parenteral therapy with enrofloxacin resulted into clinical recovery.Not Availabl