5 research outputs found
Processes of managing information infrastructure of a digital enterprise in the framework of the «Industry 4.0» concept
A study of the management of the information infrastructure of a digital enterprise is conducted within the framework of the “Industry 4.0” concept. It is determined that modern digital technologies cause an exponential growth of data flows, for the effective functioning of which the need arises to transform a classic enterprise into digital. There are new business models, network structures based on collective methods of production and consumption, which transform traditional market relations and require the development of new solutions in the field of digital enterprise management. It is noted that the use of all elements (mobility; sociality; BPM, electronic document management system ERP finance and accounting; Big Data Analytics, business analytics) of modern information and communication technologies will increase the productivity and value of enterprises. It is determined that information and communication technologies allow to effectively interact with each other in certain sectors of production and ensure the optimization of any business processes using consumerization. Modern trends in the development of digital enterprises are identified and the prerequisites for the introduction of digitalization in the business space are marked. The constituent elements of the management process of the information infrastructure of a digital enterprise are structured, on the basis of which a model of the information infrastructure management process is proposed. The objectives of the digital infrastructure are substantiated, which are indicated: to increase the speed of decision-making, to increase the variability of processes depending on the needs and characteristics of the client, to reduce the number of employees involved in the process. The methodological foundations of the process of managing the information infrastructure of a digital enterprise are deepened in the context of the “Industry 4.0” conceptПроведено дослідження процесу управління інформаційною інфраструктурою цифрового підприємства в межах концепції «Індустрія 4.0». Визначено, що сучасні цифрові технології викликають експоненціальне зростання потоків даних, для ефективного функціонування яких постає питання трансформації класичного підприємства в цифрове. З'являються нові моделі ведення бізнесу, мережеві структури, що ґрунтуються на колективних методах виробництва і споживання, трансформують традиційні ринкові відносини і вимагають вироблення нових рішень в галузі управління цифровим підприємством. Зазначено, що
використання всіх елементів (мобільність;
соціальність; BPM; система електронного
документообігу; ERP фінанси та облік; Big
Data & Analytics, бізнес-аналітика) сучас-
них інформаційно-комунікаційних тех-
нологій дозволить підвищити продуктив-
ність та цінність підприємств. Визначено,
що інформаційно-комунікаційні технології
дозволяють ефективно взаємодіяти між
собою в певних галузях виробництва та
забезпечують оптимізацію будь-яких біз-
нес-процесів за допомогою консьюмеріза-
ції. Ідентифіковано сучасні тренди розвит-
ку цифрового підприємства та окреслено
передумови до впровадження цифровізації
у бізнес-простір. Структуровано складові
елементи процесу управління інформацій-
ною інфраструктурою цифрового підпри-
ємства, на базі чого запропоновано модель
процесу управління інформаційною інфра-
структурою. Обґрунтовано цілі цифрової
інфраструктури, які зазначені: в підвищен-
ні швидкості прийняття рішень, збільшен-
ні варіативності процесів в залежності від
потреб та особливостей клієнта, зниженні
кількості залучених до процесу співробіт-
ників. Поглиблено методичні основи проце-
су управління інформаційною інфраструк-
турою цифрового підприємства в умовах
концепції «Індустрія 4.0
Additional Impact of Glucose Tolerance on Telomere Length in Persons With and Without Metabolic Syndrome in the Elderly Ukraine Population
Rationale: Association between different components of metabolic syndrome and the rate of age-related telomere shortening was reported repeatedly, although some findings are inconsistent across studies, suggesting the need for further research on the topic. In the present study, we examined relationships between different components of metabolic syndrome (MetS); glucose tolerance reflected in 2-h post-load plasma glucose (2hPG) levels and age on the leukocyte telomere length (LTL) in Ukraine population.Methods: The study was conducted on the 115 adult individuals residing in the Kyiv region (Ukraine). Among them, 79 were diagnosed with MetS according to the International Diabetes Federation definition. LTL were determined by a qPCR-based method. Multivariate logistic regression (MLR) and artificial neural networks (ANN) modeling were used for the analysis of the results. ROC-analysis was also performed to compare the predictively values of this models.Results: MetS was associated with a high (OR = 3.0 CI 1.3–6.7; p = 0.01) risk of having shorter telomeres that remained significant after adjusting for age, gender and 2hPG levels. Fasting plasma glucose (FPG) levels and other MetS components did not affect the magnitude of the relationship and did not reveal the independent influence of these factors. The level of 2hPG in turn, demonstrated a significant relationship (OR = 1.3 CI 1.0–1.6 per 1 mmol/l; p = 0.04) with LTL regardless of the presence of MetS. The non-linearity of the interactions between age, gender and 2hPG level was revealed by neural network modeling (AUC = 0.76 CI 0.68–0.84).Conclusion: Our study found that impaired glucose tolerance, but not FPG levels, affected the association between LTL and MetS, which may be also indicative for pathophysiological differences in these hyperglycemia categories. 2hPG levels can provide an opportunity for a more accurate diagnostics of MetS and for evaluating the rate of aging in patients with MetS. Further research, however, is needed to verify this assumption
Defining Patterns in the Longitudinal Load on a Train Equipped with the New Conceptual Couplers
The longitudinal-dynamic load on a railroad train has been studied at its steady motion along the track of a homogeneous profile. A value of the longitudinal loading that a train is exposed to has been established. The calculations were carried out for a train consisting of 40 similar semi-wagons. The magnitude of the longitudinal loading, in this case, is taken to equal 1.2 MN. It is important to note that when increasing the motion speed, as well as the weight of a train, the magnitude of the longitudinal load may exceed the specified value. This contributes to the additional loading on the bearing structures of cars on the train and can cause damage to them. In addition, significant longitudinal-dynamic loads contribute to disrupting the motion stability of cars in the train.In order to reduce the longitudinal-dynamic efforts in the train under operating modes, including braking, it has been proposed to use, instead of a standard automatic coupling device, a conceptual coupler. In this case, the impact's kinetic energy is damped by transforming it into the work of a viscous resistance force. This resistance is created by moving a viscous liquid through the throttle holes of the piston based on the principle of hydraulic damper operation.To substantiate the use of a conceptual coupler, the calculation has been performed based on a method for determining the strength of the coupling device through the imaginary separation of a train into two parts.Taking into consideration a coefficient of the viscous resistance, which is created by the conceptual coupler, the acceleration experienced by a train reached about 0.8 m/s2. In other words, the use of a conceptual coupler makes it possible to reduce the longitudinal loading on a train by almost 30 % compared with the standard scheme of interaction between a locomotive and cars.The rod of the conceptual coupler has been estimated for strength. It has been established that the maximum equivalent stresses do not exceed permissible limits.The proposed measures would contribute to the reduction of a dynamic load on a railroad train under the loading modes of operation. The implementation of a given concept could also contribute to bringing down the damage to railroad stock in exploitatio
First experiments on RF plasma production at relatively low magnetic fields in the LHD
The results of the first experimental series to produce a plasma using the radio frequency discharge (RF) above the ion cyclotron frequency at relatively low magnetic fields (0.5–0.6 T) in the Large Helical Device (LHD) are presented 1.43 MW of RF power produced target plasma with density up to 6 × 1018 m−3 to deuterium. Tangential NBI application into such a plasma increases plasma parameters. Electron temperatures up to ≈0.9 keV and densities up to ≈2.4 × 1019 m−3 had been achieved, and the maximum value of <βdia> was 2.6%. These experiments open possibilities for new regimes of LHD operation which are also interested to W7-X
ICRF plasma production in gas mixtures in the Uragan-2M stellarator
This paper summarizes previous results and presents new studies on the ICRF plasma creation both in pure gases and gas mixtures. In all the experiments, the two-strap antenna was operated in monopole phasing with applied RF power of ∼100 kW. The research for plasma creation was carried out at RF frequencies near the fundamental hydrogen cyclotron harmonic