51 research outputs found
Improved redshifts for SDSS quasar spectra
A systematic investigation of the relationship between different redshift
estimation schemes for more than 91000 quasars in the Sloan Digital Sky Survey
(SDSS) Data Release 6 (DR6) is presented. The publicly available SDSS quasar
redshifts are shown to possess systematic biases of Dz/(1+z)>=0.002 (600km/s)
over both small (dz~0.1) and large (dz~1) redshift intervals. Empirical
relationships between redshifts based on i) CaII H & K host galaxy absorption,
ii) quasar [OII] 3728, iii) [OIII] 4960,5008 emission, and iv)
cross-correlation (with a master quasar template) that includes, at increasing
quasar redshift, the prominent MgII 2799, CIII] 1908 and CIV 1549 emission
lines, are established as a function of quasar redshift and luminosity. New
redshifts in the resulting catalogue possess systematic biases a factor of ~20
lower compared to the SDSS redshift values; systematic effects are reduced to
the level of Dz/(1+z)<10^-4 (30km/s) per unit redshift, or <2.5x10^-5 per unit
absolute magnitude. Redshift errors, including components due both to internal
reproducibility and the intrinsic quasar-to-quasar variation among the
population, are available for all quasars in the catalogue. The improved
redshifts and their associated errors have wide applicability in areas such as
quasar absorption outflows, quasar clustering, quasar-galaxy clustering and
proximity-effect determinations.Comment: Accepted to MNRAS. The QSO redshift catalogue and QSO template
spectrum can be downloaded from ftp://ftp.ast.cam.ac.uk/pub/phewett/ until
1st May 201
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Identifying Motor, Emotional-Behavioral, and Cognitive Deficits that Comprise the Triad of HD Symptoms from Patient, Caregiver, and Provider Perspectives
Background: The objective of this study was to identify important attributes associated with the triad of symptoms (cognition, emotional–behavioral, and motor) of Huntington's disease (HD) from patient, caregiver, and medical provider perspectives to facilitate development of a new disease‐specific, health‐related quality of life (HRQOL) instrument.
Methods: We conducted a targeted literature review of HD and HRQOL instruments, expert surveys, and patient and caregiver phone‐based interviews to extract information on the symptoms and issues most relevant to the HD symptom triad (HD triad). The data collected from these sources were used to generate themes and subdomains and to develop an integrated schema that highlights the key dimensions of the triad.
Results: The search identified the following areas: emotional functioning/behavioral changes (e.g., positive emotions, sadness/depression); cognitive functioning (e.g., memory/learning, attention/comprehension); physical functioning (e.g., motor functioning, medication); social functioning (e.g., leisure, interpersonal relationships); end‐of‐life concerns/planning; and gene testing. Fifteen individuals diagnosed with HD and 16 HD caregivers, recruited from several Huntington's Disease Society of America support group networks, completed phone interviews. Nineteen US medical providers who specialize in HD completed the online survey. Twenty‐six subdomains of the HD symptom triad (seven cognition, 12 emotional–behavioral, and seven motor) emerged relatively consistently across patient, caregiver, and provider samples. These included movements/chorea, memory impairment, depression, and anxiety.
Discussion: Based on an integrated, mixed‐methods approach, important HD triad symptom were identified and organized into a guiding schema. These patient‐, caregiver‐, and provider‐triangulated data served as the basis for development of a HD‐specific HRQOL instrument, the HD‐PRO‐TRIAD™
The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment
The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in
operation since July 2014. This paper describes the second data release from
this phase, and the fourteenth from SDSS overall (making this, Data Release
Fourteen or DR14). This release makes public data taken by SDSS-IV in its first
two years of operation (July 2014-2016). Like all previous SDSS releases, DR14
is cumulative, including the most recent reductions and calibrations of all
data taken by SDSS since the first phase began operations in 2000. New in DR14
is the first public release of data from the extended Baryon Oscillation
Spectroscopic Survey (eBOSS); the first data from the second phase of the
Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2),
including stellar parameter estimates from an innovative data driven machine
learning algorithm known as "The Cannon"; and almost twice as many data cubes
from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous
release (N = 2812 in total). This paper describes the location and format of
the publicly available data from SDSS-IV surveys. We provide references to the
important technical papers describing how these data have been taken (both
targeting and observation details) and processed for scientific use. The SDSS
website (www.sdss.org) has been updated for this release, and provides links to
data downloads, as well as tutorials and examples of data use. SDSS-IV is
planning to continue to collect astronomical data until 2020, and will be
followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14
happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov
2017 (this is the "post-print" and "post-proofs" version; minor corrections
only from v1, and most of errors found in proofs corrected
The structure of post-starburst galaxies at 0.5 < z < 2: evidence for two distinct quenching routes at different epochs
We present an analysis of the structure of post-starburst (PSB) galaxies in the redshift range 0.5 1), PSBs are typically massive (M* > 10^10 Msun), very compact and exhibit high Sérsic indices, with structures that differ significantly from their star-forming progenitors but are similar to massive passive galaxies. In contrast, at lower redshift (0.5 1 have been recently quenched during a major disruptive event (e.g. merger or protogalactic collapse) that formed a compact remnant, while at z < 1 an alternative less disruptive process is primarily responsible. Our results suggest that high-z PSBs are an intrinsically different population to those at lower redshifts, and indicate different quenching routes are active at different epochs
MSL2 variants lead to a neurodevelopmental syndrome with lack of coordination, epilepsy, specific dysmorphisms, and a distinct episignature.
Epigenetic dysregulation has emerged as an important etiological mechanism of neurodevelopmental disorders (NDDs). Pathogenic variation in epigenetic regulators can impair deposition of histone post-translational modifications leading to aberrant spatiotemporal gene expression during neurodevelopment. The male-specific lethal (MSL) complex is a prominent multi-subunit epigenetic regulator of gene expression and is responsible for histone 4 lysine 16 acetylation (H4K16ac). Using exome sequencing, here we identify a cohort of 25 individuals with heterozygous de novo variants in MSL complex member MSL2. MSL2 variants were associated with NDD phenotypes including global developmental delay, intellectual disability, hypotonia, and motor issues such as coordination problems, feeding difficulties, and gait disturbance. Dysmorphisms and behavioral and/or psychiatric conditions, including autism spectrum disorder, and to a lesser extent, seizures, connective tissue disease signs, sleep disturbance, vision problems, and other organ anomalies, were observed in affected individuals. As a molecular biomarker, a sensitive and specific DNA methylation episignature has been established. Induced pluripotent stem cells (iPSCs) derived from three members of our cohort exhibited reduced MSL2 levels. Remarkably, while NDD-associated variants in two other members of the MSL complex (MOF and MSL3) result in reduced H4K16ac, global H4K16ac levels are unchanged in iPSCs with MSL2 variants. Regardless, MSL2 variants altered the expression of MSL2 targets in iPSCs and upon their differentiation to early germ layers. Our study defines an MSL2-related disorder as an NDD with distinguishable clinical features, a specific blood DNA episignature, and a distinct, MSL2-specific molecular etiology compared to other MSL complex-related disorders
Narrow associated QSO absorbers: clustering, outflows and the line-of-sight proximity effect
Using data from the Sloan Digital Sky Survey data release 3 (SDSS DR3) we
investigate how narrow (<700km/s) CIV and MgII quasar absorption line systems
are distributed around quasars. The CIV absorbers lie in the redshift range 1.6
< z < 4 and the MgII absorbers in the range 0.4<z<2.2. By correlating absorbers
with quasars on different but neighbouring lines-of-sight, we measure the
clustering of absorbers around quasars on comoving scales between 4 and 30Mpc.
The observed comoving correlation lengths are r_o~5h^-1Mpc, similar to those
observed for bright galaxies at these redshifts. Comparing with correlations
between absorbers and the quasars in whose spectra they are identified then
implies: (i) that quasars destroy absorbers to comoving distances of ~300kpc
(CIV) and ~800kpc (MgII) along their lines-of-sight; (ii) that >40% of CIV
absorbers within 3,000km/s of the QSO are not a result of large-scale
clustering but rather are directly associated with the quasar itself; (iii)
that this intrinsic absorber population extends to outflow velocities of order
12,000km/s; (iv) that this outflow component is present in both radio-loud and
radio-quiet quasars; and (v) that a small high-velocity outflow component is
observed in the MgII population, but any further intrinsic absorber component
is undetectable in our clustering analysis. We also find an indication that
absorption systems within 3,000km/s are more abundant for radio-loud than for
radio-quiet quasars. This suggests either that radio-loud objects live in more
massive halos, or that their radio activity generates an additional
low-velocity outflow, or both.Comment: 16 pages, 20 figures, submitted to MNRA
The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the Extended Baryon Oscillation Spectroscopic Survey and from the Second Phase of the Apache Point Observatory Galactic Evolution Experiment
The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since 2014 July. This paper describes the second data release from this phase, and the 14th from SDSS overall (making this Data Release Fourteen or DR14). This release makes the data taken by SDSS-IV in its first two years of operation (2014–2016 July) public. Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey; the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data-driven machine-learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from the SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS web site (www.sdss.org) has been updated for this release and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020 and will be followed by SDSS-V
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The Fifteenth Data Release of the Sloan Digital Sky Surveys: First Release of MaNGA-derived Quantities, Data Visualization Tools, and Stellar Library
Twenty years have passed since first light for the Sloan Digital Sky Survey (SDSS). Here, we release data taken by the fourth phase of SDSS (SDSS-IV) across its first three years of operation (2014 July–2017 July). This is the third data release for SDSS-IV, and the 15th from SDSS (Data Release Fifteen; DR15). New data come from MaNGA—we release 4824 data cubes, as well as the first stellar spectra in the MaNGA Stellar Library (MaStar), the first set of survey-supported analysis products (e.g., stellar and gas kinematics, emission-line and other maps) from the MaNGA Data Analysis Pipeline, and a new data visualization and access tool we call "Marvin." The next data release, DR16, will include new data from both APOGEE-2 and eBOSS; those surveys release no new data here, but we document updates and corrections to their data processing pipelines. The release is cumulative; it also includes the most recent reductions and calibrations of all data taken by SDSS since first light. In this paper, we describe the location and format of the data and tools and cite technical references describing how it was obtained and processed. The SDSS website (www.sdss.org) has also been updated, providing links to data downloads, tutorials, and examples of data use. Although SDSS-IV will continue to collect astronomical data until 2020, and will be followed by SDSS-V (2020–2025), we end this paper by describing plans to ensure the sustainability of the SDSS data archive for many years beyond the collection of data
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