Hydrodynamics and water quality modelling in a regulated river segment: application on the instream flow definition

The aim of this paper is to present a global study on the hydrodynamics, water quality and their influence on aquatic fauna. The case study was conducted on a segment of the Lima river (North Portugal), downstream of the Touvedo dam, which was mainly constructed for hydroelectric power production.http://www.sciencedirect.com/science/article/B6VBS-4BHVGYD-7/1/7765917f49c0a6b3764cf34a8227cfc

Effect of mercury in virgin, pregnant and lactating rats

Mercury is a toxic metal widely used in industrial activities. In Brazil, cases of mercury contamination occur mainly in the Amazon region, where mercury is used in mining to amalgamate the gold; people is so exposed to mercury occupationally and through the consumption of contaminated fish and water [1]. Mercury has a non uniform distribution after absorption, being accumulated mainly in the kidneys causing renal injury [2]. Numerous metabolic changes occur physiologically in pregnancy and lactation periods and induce a different response to exogenous substances, respect virgin animals. At this aim, we evaluated the pathogenetic mechanism, at kidney level, involved in the different responses of virgin, pregnant and lactating rats exposed to a single dose of mercury. Interestingly, the mercury-induced nephrotoxicity differs among pregnant or lac- tating respect virgin rats. In particular, virgin rat showed kidney histopathological alterations including interstitial fibrosis and tubular damages and an altered modulation of heat shock proteins, damages that correlates with the overall loss of renal function. The distinctive responses between pregnant and lactating respect virgin rats observed in our study may be associated with some of several physiological changes that occur during pregnancy or lactation periods

Mastoiditis and facial paralysis as initial manifestations of Wegener's Granulomatosis

Wegener's Granulomatosis (WG) is characterized by necrotizing granulomas and vasculitis. If left untreated, the prognosis is poor - a 90% mortality rate within 2 years. Several authors have described the otologic manifestations of WG; these authors, however, have not mentioned the stage of the disease in which these findings present - whether as initial manifestations or subsequent to other findings. Aim: To describe three confirmed cases of WG with mastoiditis as the first manifestation, progressing to peripheral facial paralysis (PFP). Material and Method: A clinical series study. Patients diagnosed with WG that initially presented with otologic findings are described. Results: The three cases presented with unilateral otalgia, otorrhea, and hearing loss associated with ipsilateral PFP. None recovered in spite of the treatment; an investigation of associated diseases was therefore undertaken. Positive ANCA-C titers where detected in all patients, confirming the diagnosis of WG. Clinical improvement was seen after treatment of WG; the PFP regressed and hearing thresholds improved partially. Conclusion: Complications of otitis media (mastoiditis and PFP) that do not respond to the usual treatment require an investigation of associated diseases; WG should be included for an early diagnosis to change the prognosis in these patients.A Granulomatose de Wegener (GW) é caracterizada por granulomas necrotizantes e vasculite. Sem tratamento a doença tem prognóstico pobre com índice de mortalidade de 90% em 2 anos. Diversos autores citam as manifestações otológicas no curso da GW, entretanto não é especificado em que momento da doença elas apareceram, isto é, se como manifestação inicial ou subsequente a outros achados. Objetivo: Descrever três casos confirmados de GW que apresentaram inicialmente mastoidite e evoluíram com paralisia facial periférica (PFP). Material e Método: Estudo de série de casos. Pacientes diagnosticados com GW que apresentaram inicialmente manifestações otológicas são descritos. Resultados: Os três casos descritos abriram o quadro com otalgia, otorreia e hipoacusia unilateral, associada a paralisia facial periférica ipsilateral. Tiveram resposta inadequada aos tratamentos instituídos o que motivou uma investigação de outras doenças associadas. Nessas circunstâncias, detectaram-se títulos positivos de ANCA-C em todos pacientes, confirmando-se o diagnóstico de GW, após período variável de investigação. Institui-se o tratamento para GW observando-se melhora do quadro clínico, regressão da PFP e melhora parcial dos limiares auditivos. Conclusão: Complicações de otites médias agudas (mastoidite e PFP) refratárias as terapêuticas habituais impõem a investigação de doenças associadas e a GW deverá ser pesquisada para que se possa fazer o diagnóstico o mais precocemente possível, alterando desta forma o prognóstico destes pacientes.UNIFESP-EPM Departamento de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoUNIFESP, EPM, Depto. de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoSciEL

Panorama da atuação do profissional de secretariado executivo na Universidade Federal do Pará através da gestão por competências

As Instituições Federais de Ensino Superior [IFES] caracterizam-se pela singularidade na execução de tarefas no âmbito do ensino, pesquisa, extensão e prestação de serviços à sociedade, com objetivos de produção de conhecimento e formação de profissionais que contribuam para o desenvolvimento social, cenário este no qual o secretário-executivo (SE) está inserido. O estudo tem como objetivo geral analisar o panorama do cargo de secretário executivo da Universidade Federal do Pará [UFPA], de acordo com a distribuição dos profissionais na estrutura e competências organizacionais. O referencial teórico discorre acerca da gestão universitária pública e da atuação do profissional de secretariado executivo nesse contexto. A metodologia contou com a abordagem de métodos mistos, com técnicas de coleta de levantamento e questionário aplicado a 31 SE sobre competências desenvolvidas na UFPA, contando com técnicas de análise de conteúdo, triangulação e distribuição de frequências. Como resultados, verificou-se que a distribuição dos SE, embora razoavelmente adequada na estrutura organizacional da UFPA, ainda é desproporcional; que as principais competências desenvolvidas são Redação Oficial, Tramitar Documentos e Processos, Arquivar Documentos, Análise de Documentos, Atualização de Informações e Dados, Fluxos de Processos, Delegar Tarefas, Assessoramento de Reuniões, Oferecer Feedback e Negociação e que predominam as competências técnicas em detrimento das competências gerenciais atribuídas ao perfil do SE

Renal Fornix Rupture Due To Acute Ureteral Obstruction

Background: Renal fornix rupture with fluid extravasation is a rare complication in cases of ureteral obstruction, which is usually caused by obstructive ureterolithiasis. The symptoms of renal fornix rupture are not very specific and can easily go unnoticed due to their underlying cause. Case representation: The present article reports a case of a patient of a 70-year-old, male, who was diagnosed with a ruptured renal fornix due to acute ureteral obstruction, following clinical assessment and a non-contrast CT scan. The proposed course of action was the endoscopic placement of a double J ureteral catheter. Conclusion: In the case described, the conservative treatment that was chosen by passing a double J catheter through the left ureter, for the patient proved to be an alternative to surgical treatment in the acute event, reducing the risk of possible complications from the operation. It was possible to conclude that although renal fornix rupture is a rare emergency with multiple etiologies, conservative treatment with urinary diversion using a double J ureteral stent was effective in solving the patient\u27s acute condition

Saneamento solidário – projetos hidrossanitários/ Solidary sanitation - hydrosanitary projects

O saneamento básico é definido como o conjunto de serviços, infraestruturas e instalações de abastecimento de água, esgotamento sanitário, limpeza urbana e manejo de resíduos sólidos e drenagem de águas pluviais urbanas, sendo a universalização do acesso a estes serviços um direito assegurado a todos. Tal atividade é uma área de atuação da Engenharia Civil, através de, entre outras coisas, desenvolvimento de projetos hidrossanitários. Desta forma, este trabalho apresenta projetos hidrossanitários desenvolvidos para duas comunidades diferentes em parceria com instituições filantrópicas, em que uma equipe de acadêmicos do curso de Engenharia Civil da Universidade Estadual de Ponta Grossa realizou os referidos projetos. Tais projetos seguiram as normas técnicas apresentadas pela ABNT e tiveram como principal benefício à experiência positiva dos professores e acadêmicos, futuros profissionais, no que tange a importância do envolvimento de engenheiros civis em aspectos sociais e humanos

Calcium sulfate fillers and binders in Portuguese 15th and 16th centuries: Ground layers from a family painting workshop — Study by multianalytical spectroscopic techniques

This study presents results on a developed methodology to characterize ground layers in Portuguese workshops. In this work a set of altarpieces of the 15th and 16th centuries, assigned to Coimbra painting workshop was studied, overall the masters Vicente Gil (doc. Coimbra 1498–1525), Manuel Vicente (doc. Coimbra 1521–1530) and Bernardo Manuel (act. c. 1559–94), father, son and grandson, encompassing from late gothic to mannerist periods. The aim of the study is to compare ground layers, fillers and binders of Coimbra workshop, and to correlate their characteristics to understand the technical evolution of this family of painters, using complementary microscopic techniques. The cross-sections from the groups of paintings were examined by optical microscopy and the results were integrated through the analysis obtained by μ-X–ray diffraction, scanning electron microscopy with energy dispersive X–ray Spectrometry, μ-confocal Raman and occasionally with μ-Fourier transform infrared spectroscopy imaging. Ground layers are of calcium sulfate, present as gesso grosso (mainly anhydrite with small amounts of gypsum) in the first and last phases of the workshop and gesso mate (mainly gypsum with small amounts of anhydrite) in an intermediate period. Binders have protein and oleic characteristics

Novas Formas de Atuação do Profissional de Secretariado Executivo

O presente artigo trata das novas formas de atuação do profissional de Secretariado Executivo no mercado de trabalho. Para mapear e compreender essas novas formas foi traçado um paralelo descritivo entre as características de cada nova área de atuação. Para isto foi adotada a pesquisa aplicada, sendo classificada como exploratória e descritiva, por meio de uma pesquisa bibliográfica, com tratamento feito pela análise de conteúdo. A partir disso, foram trabalhados cinco critérios para o mapeamento dessas novas formas de atuação: definição e esclarecimentos de cada atuação; perfil profissional requerido; expectativas do mercado e locais onde podem ser encontradas tais demandas. Para o atendimento das finalidades do trabalho, foram abordadas as seguintes formas de atuação: Assessoria – tanto em sua gênese bem como em formas atuais de exercício da função, como home office, escritórios virtuais e pool secretarial, consultoria secretarial e a área cooperativista. As conclusões apontam que tais áreas são pouco exploradas, mas já é possível perceber uma movimentação dos profissionais do secretariado iniciando suas atividades nessas áreas

Combined Toxicity of Methylparaben and Propylparaben in Artemia salina and Allium cepa Applying Experimental Design

Parabens are used as preservatives in sanitizers and cosmetic products causing environmental concern, because presented potential as endocrine disrupters. Among these compounds, the most used are methylparaben and propylparaben. Thus, a study was proposed to evaluate the interaction between different concentrations (mmol L-1) of the variables methylparaben [MP] and propylparaben [PP], against the acute toxicity of the microcrustacean Artemia salina (A. salina) and Allium cepa (A. cepa) applying the 22 factorial design with an added center point. Responses were used: percent A. salina mortality (% mortality), A. cepa root growth inhibition (% root inhibition) and mitotic index (%MI). For A. salina, after 72 hours of exposure with the combination of concentration ([MP] and [PP] = 0.8 mmol L−1) caused an 80% mortality. While, A. cepa a high cytotoxicity was observed with the mixture of Parabens, exhibiting 72.3% root growth inhibition at [MP] = 1.2 mmol L-1 with [PP] = 1.2 mmol L-1. In contrast, for response %MI at [MP] = 0.3 mmol L-1 with [PP] = 0.3 mmol L-1, 2.5 %MI with 36% inhibition. In this context, parabens demonstrated high toxicity for A. salina and cytotoxicity for A. cepa, based on the interaction with the effect of the concentrations

Clube Português do Pâncreas Recommendations for Chronic Pancreatitis: Medical, Endoscopic, and Surgical Treatment (Part II)

Chronic pancreatitis (CP) is a complex disease that should be treated by experienced teams of gastroenterologists, radiologists, surgeons, and nutritionists in a multidisciplinary environment. Medical treatment includes lifestyle modification, nutrition, exocrine and endocrine pancreatic insufficiency correction, and pain management. Up to 60% of patients will ultimately require some type of endoscopic or surgical intervention for treatment. However, regardless of the modality, they are often ineffective unless smoking and alcohol cessation is achieved. Surgery retains a major role in the treatment of CP patients with intractable chronic pain or suspected pancreatic mass. For other complications like biliary or gastroduodenal obstruction, pseudocyst drainage can be performed endoscopically. The recommendations for CP were developed by Clube Português do Pâncreas (CPP), based on literature review to answer predefined topics, subsequently discussed and approved by all members of CPP. Recommendations are separated in two parts: "chronic pancreatitis etiology, natural history, and diagnosis," and "chronic pancreatitis medical, endoscopic, and surgical treatment." This abstract pertains to part II.info:eu-repo/semantics/publishedVersio