3 research outputs found
Carotidynie: eine seltene Manifestation einer nicht so seltenen Erkrankung
Wir präsentieren den Fall eines 49-jährigen Patienten mit linksseitiger Carotidynie. Als Ursache fand sich eine Lymphknotentuberkulose. Unter tuberkulostatischer Therapie zeigte sich eine rasche Besserung der Symptome.
Schlüsselwörter:Lymphknotentuberkulose, Carotidynie, Peri-Vaskulitis, granulomatöse Lymphadenitis
We present the case of a 49-year-old patient who suffered from carotidynia, due to tuberculous lymphadenitis. Under tuberculostatic treatment clinical symptoms improved rapidly.
Schlüsselwörter:Tuberculous lymphadenitis, carotidynia, peri-vasculitis, granulomatous lymphondeni
Impact of the new TNM Staging System (8th edition) on oral tongue cancers
AIM OF THE STUDY
For tumours of the oral tongue, the most recent 8th edition of the AJCC/UICC staging system has introduced depth of infiltration (DOI) as a novel parameter. With this study we wanted to investigate its impact regarding this risk stratification compared with the preceding 7th edition.
METHODS
Between 2008 and 2017, 161 patients of two tertiary referral centres in Switzerland (Kantonsspital St. Gallen and University Hospital Zurich) with T1 N0 or T2 N0 tongue cancers were enrolled in this study. The primary tumours were restaged according to the 8th edition of the TNM classification. Kaplan-Meier curves for overall and disease-specific survival were calculated.
RESULTS
According to the 7th edition, of the 161 patients, 102 were staged after surgery as pT1 (stage I) and 59 as pT2 (stage II). According to the 8th edition, 36 patients (22.4%) were re-staged to a higher stage. Of these 36 patients, 8 (22.2%) experienced a recurrence, and 9 (25%) died. In the remaining, not re-staged group, 20 patients (16.0%) experienced a recurrence (p = 0.55) and 14 (11.2%) died (p = 0.025*). The 7th edition showed a statistically significant difference between pT1 and pT2 tumours for overall survival (p = 0.025), but not for disease-specific survival (p = 0.091), whereas the 8th edition was able to well discriminate between pT1, pT2 and pT3 for both overall (pT1 vs pT2, p = 0.016*; pT2 vs pT3, p = 0.031*) and disease-specific survival (pT1 vs pT2, p = 0.037*; pT2 vs pT3, p = 0.023*).
CONCLUSION
The recent TNM 8th edition provides a more accurate prediction of overall and disease-specific survival for this subgroup of patients. Hence, a more aggressive treatment should be considered for patients re-staged to pT3 due to depth of infiltration
Epithelial cyst in the posterior triangle of the neck: atypical branchial cyst or cystic lymph node metastasis?
We report the case of a 66-year-old man with a cervical neck mass located behind the left sternocleidomastoid muscle. To exclude malignancy, a full workup, including clinical, radiological, and cytological examination, was performed but failed to provide a definitive diagnosis. Histological analysis following excisional biopsy revealed a benign epithelial cyst, consistent with an atypically located branchial cyst. We describe an approach to the management of these neck masses and discuss several theories of the etiology of branchial cysts and how they may come to be abnormally located