55 research outputs found
When in Rome Think Like a Roman: Empirical Evidence and Implications of Temporarily Adopting Dialectical Thinking
As a result of increasing globalization, people are exposed to an even greater extent to other cultures, making it possible for individuals to assimilate mindsets that are typical of another culture. Recent work on extracultural cognition has shown that immediate cultural contexts exert powerful influences on cognition and behavioral patterns. This chapter reviews empirical support for extracultural cognition. Specifically, the chapter focuses on dialectical thinking and the well-established finding in the cultural literature that Westerners tend to anticipate linear continuity in the environment and East Asians anticipate change in existing patterns. Research shows, though, that cultural cues may shift these tendencies and—at least temporarily—alter cognitive mindsets to reflect the cognitions of another culture. After a review of the literature, the chapter addresses the implications of extracultural cognition for understanding the influence of dialectical thinking on judgment and decision-making
Adopting a Group Attention Perspective: An Exploration of Moderators and Future Directions
Shteynberg (this issue) reviews how group attention increases the psychological prominence of the information observed in group settings, serves to better embed descriptive norms making them more dominant in people’s cognitions, and acts as an axis of group communication and cooperation. We find the research on group attention compelling and an interesting addition to this special issue on Intersubjective Norms. The findings regarding group attention suggest that it generally functions like a cognitive heuristic (i.e., an automatic process that occurs largely without people’s awareness or control). Yet, we question whether there are conditions under which individuals would not use group attention to determine descriptive norms and instead use other methods for focusing their attention (possibly moving them toward more deliberative cognitive processing). In this comment, we aim to highlight and suggest potential moderators of the phenomenon and directions for future research on this topic
Adopting a Group Attention Perspective: An Exploration of Moderators and Future Directions
Shteynberg (this issue) reviews how group attention increases the psychological prominence of the information observed in group settings, serves to better embed descriptive norms making them more dominant in people’s cognitions, and acts as an axis of group communication and cooperation. We find the research on group attention compelling and an interesting addition to this special issue on Intersubjective Norms. The findings regarding group attention suggest that it generally functions like a cognitive heuristic (i.e., an automatic process that occurs largely without people’s awareness or control). Yet, we question whether there are conditions under which individuals would not use group attention to determine descriptive norms and instead use other methods for focusing their attention (possibly moving them toward more deliberative cognitive processing). In this comment, we aim to highlight and suggest potential moderators of the phenomenon and directions for future research on this topic
Rural Australian community pharmacists' views on complementary and alternative medicine: a pilot study
<p>Abstract</p> <p>Background</p> <p>Complementary and alternative medicines (CAMs) are being used increasingly across the world. In Australia, community pharmacists are a major supplier of these products but knowledge of the products and interactions with other medicines is poor. Information regarding the use of CAMs by metropolitan pharmacists has been documented by the National Prescribing Service (NPS) in Australia but the views of rural/regional community pharmacists have not been explored. The aim of this pilot study was to explore the knowledge, attitudes and information seeking of a cohort of rural community pharmacists towards CAMs and to compare the findings to the larger NPS study.</p> <p>Methods</p> <p>A cross sectional self-administered postal questionnaire was mailed to all community pharmacists in one rural/regional area of Australia. Using a range of scales, data was collected regarding attitudes, knowledge, information seeking behaviour and demographics.</p> <p>Results</p> <p>Eighty eligible questionnaires were returned. Most pharmacists reported knowing that they should regularly ask consumers if they are using CAMs but many lacked the confidence to do so. Pharmacists surveyed for this study were more knowledgeable in regards to side effects and interactions of CAMs than those in the NPS survey. Over three quarters of pharmacists surveyed reported sourcing CAM information at least several times a month. The most frequently sought information was drug interactions, dose, contraindications and adverse effects. A variety of resources were used to source information, the most popular source was the internet but the most useful resource was CAM text books.</p> <p>Conclusions</p> <p>Pharmacists have varied opinions on the use of CAMs and many lack awareness of or access to good quality CAMs information. Therefore, there is a need to provide pharmacists with opportunities for further education. The data is valuable in assisting interested stakeholders with the development of initiatives to address the gaps in attitudes, knowledge and to improve effectiveness of information seeking behaviour.</p
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
Introduction: Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved in DNA double-strand break repair, DNA alterations that can be caused by exposure to reactive oxygen species, a main source of which are mitochondria. Mitochondrial genome variations affect electron transport chain efficiency and reactive oxygen species production. Individuals with different mitochondrial haplogroups differ in their metabolism and sensitivity to oxidative stress. Variability in mitochondrial genetic background can alter reactive oxygen species production, leading to cancer risk. In the present study, we tested the hypothesis that mitochondrial haplogroups modify breast cancer risk in BRCA1/2 mutation carriers. Methods: We genotyped 22,214 (11,421 affected, 10,793 unaffected) mutation carriers belonging to the Consortium of Investigators of Modifiers of BRCA1/2 for 129 mitochondrial polymorphisms using the iCOGS array. Haplogroup inference and association detection were performed using a phylogenetic approach. ALTree was applied to explore the reference mitochondrial evolutionary tree and detect subclades enriched in affected or unaffected individuals. Results: We discovered that subclade T1a1 was depleted in affected BRCA2 mutation carriers compared with the rest of clade T (hazard ratio (HR) = 0.55; 95% confidence interval (CI), 0.34 to 0.88; P = 0.01). Compared with the most frequent haplogroup in the general population (that is, H and T clades), the T1a1 haplogroup has a HR of 0.62 (95% CI, 0.40 to 0.95; P = 0.03). We also identified three potential susceptibility loci, including G13708A/rs28359178, which has demonstrated an inverse association with familial breast cancer risk. Conclusions: This study illustrates how original approaches such as the phylogeny-based method we used can empower classical molecular epidemiological studies aimed at identifying association or risk modification effects.Peer reviewe
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Harnessing the NEON data revolution to advance open environmental science with a diverse and data-capable community
It is a critical time to reflect on the National Ecological Observatory Network (NEON) science to date as well as envision what research can be done right now with NEON (and other) data and what training is needed to enable a diverse user community. NEON became fully operational in May 2019 and has pivoted from planning and construction to operation and maintenance. In this overview, the history of and foundational thinking around NEON are discussed. A framework of open science is described with a discussion of how NEON can be situated as part of a larger data constellation—across existing networks and different suites of ecological measurements and sensors. Next, a synthesis of early NEON science, based on >100 existing publications, funded proposal efforts, and emergent science at the very first NEON Science Summit (hosted by Earth Lab at the University of Colorado Boulder in October 2019) is provided. Key questions that the ecology community will address with NEON data in the next 10 yr are outlined, from understanding drivers of biodiversity across spatial and temporal scales to defining complex feedback mechanisms in human–environmental systems. Last, the essential elements needed to engage and support a diverse and inclusive NEON user community are highlighted: training resources and tools that are openly available, funding for broad community engagement initiatives, and a mechanism to share and advertise those opportunities. NEON users require both the skills to work with NEON data and the ecological or environmental science domain knowledge to understand and interpret them. This paper synthesizes early directions in the community’s use of NEON data, and opportunities for the next 10 yr of NEON operations in emergent science themes, open science best practices, education and training, and community building
Adopting a Group Attention Perspective: An Exploration of Moderators and Future Directions
Shteynberg (this issue) reviews how group attention increases the psychological prominence of the information observed in group settings, serves to better embed descriptive norms making them more dominant in people’s cognitions, and acts as an axis of group communication and cooperation. We find the research on group attention compelling and an interesting addition to this special issue on Intersubjective Norms. The findings regarding group attention suggest that it generally functions like a cognitive heuristic (i.e., an automatic process that occurs largely without people’s awareness or control). Yet, we question whether there are conditions under which individuals would not use group attention to determine descriptive norms and instead use other methods for focusing their attention (possibly moving them toward more deliberative cognitive processing). In this comment, we aim to highlight and suggest potential moderators of the phenomenon and directions for future research on this topic
When in Rome Think Like a Roman: Empirical Evidence and Implications of Temporarily Adopting Dialectical Thinking
As a result of increasing globalization, people are exposed to an even greater extent to other cultures, making it possible for individuals to assimilate mindsets that are typical of another culture. Recent work on extracultural cognition has shown that immediate cultural contexts exert powerful influences on cognition and behavioral patterns. This chapter reviews empirical support for extracultural cognition. Specifically, the chapter focuses on dialectical thinking and the well-established finding in the cultural literature that Westerners tend to anticipate linear continuity in the environment and East Asians anticipate change in existing patterns. Research shows, though, that cultural cues may shift these tendencies and—at least temporarily—alter cognitive mindsets to reflect the cognitions of another culture. After a review of the literature, the chapter addresses the implications of extracultural cognition for understanding the influence of dialectical thinking on judgment and decision-making
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