Takayasu arteritis with an initial presentation of chronic monoarthritis mimicking oligoarticular juvenile idiopathic arthritis

Patients with Takayasu arteritis (TA) generally present with non-specific symptoms that, if unrecognized and untreated, may develop vessel stenosis and/or aneurysm. There is limited data regarding chronic monoarthritis as the initial presentation in children with TA. We report a 6-yearold girl diagnosed and treated as oligoarticular juvenile idiopathic arthritis (JIA). She later developed stroke with malignant hypertension and was definitively diagnosed with TA. She additionally developed proteinuria secondary to focal segmental glomerulosclerosis. This is the report of a patient with chronic monoarthritis mimicking oligoarticular JIA which chronic monoarthritis was the presentation of TA. Since JIA is a diagnosis of exclusion, any atypical features of oligoarticular JIA should illuminate the possibility of an alternative diagnosis. Our literature review focused on musculoskeletal presentations of children with TA

Enhancing Adolescent Self-Esteem: A Pilot Randomized Controlled Trial of the Online Mindfulness-Based Intervention Program (MBSI Online)

Objective: This study aimed to develop and assess the effectiveness of the MBSI online program in enhancing selfesteem, mindfulness, and resilience among adolescents, while also evaluating its feasibility and participant satisfaction. Materials and Methods: The MBSI online program is an adapted form of mindfulness-based interventions (MBIs), developed by integrating specific aspects of mindfulness that are related to self-esteem and the core processes of Acceptance and Commitment Therapy (ACT), following consultations with mindfulness experts and program trials. The study enrolled 70 adolescents aged 15 to 18 years with low to moderate self-esteem, from diverse Thai regions. Participants were randomly assigned and equally allocated to intervention and waiting-list control groups. The intervention group underwent an 8-week MBSI online program. Self-esteem, mindfulness, and resilience were assessed at baseline, week 4, week 8, 1 month, and 3 months post-intervention. Results: The self-esteem, mindfulness, and resilience scores within the intervention group have significantly increased over time compared to baseline on week 4, week 8, 1 month, and 3 months post-intervention (p < 0.001). Furthermore, between-group comparisons revealed statistically significant improvements in self-esteem, mindfulness, and resilience (p < 0.05) at corresponding intervals, with medium to large effect sizes. The dropout rate was 25.7%, while participant satisfaction with the MBSI online program was remarkably high, averaging 4.73 out of 5, with 76.9% expressing the highest level of satisfaction. Conclusion: The MBSI online program significantly improved self-esteem, mindfulness, and resilience in adolescents, achieving high participant satisfaction. This program presents a valuable intervention for adolescents with low selfesteem, aiming to prevent psychological issues stemming from diminished self-esteem

Fault Investigation and Trial

Locating bugs is one of the most time-consuming tasks in debugging. Though external resources, such as explicit knowledge bases or formal specifications, can reduce the debugging time, this information either may not be readily available or may be too limited for real-world software. So in general, most debuggers try to reduce the time by providing analysis tools for the programmer to reduce the search space for bugs and to guess at the bug type, location, or both. We review the current state-of-the-art in debugging and point out three shortcomings that deserve more attention. First, the programmer has to perform the analysis and keep track of the results himself while he tries to locate faults. Second, the programmer needs (but lacks) automated decision support to help him evaluate program behavior as he tries to reduce the search space for bugs. Third, the debuggers that support fault location guessing do not point out the statements most likely to be faulty. Our objective is to redu..

Capital Requirements of the Steel Industry, 1958 to 1970.

Ph.D.FinanceUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/156707/1/5903966.pd

Enhancing Debugging Technology

This dissertation presents a new debugging assistant called a Debugging Critic. As an alternative to an automated debugging oracle, the debugging critic evaluates hypotheses about fault locations. if it cannot confirm that the code at the hypothesized location contains a fault, it formulates an alternative hypothesis about the location of a faulty statement or the location of omitted statements. The debugging critic derives knowledge of possible locations of a fault that manifested itself under a given test case from failure symptoms. It derives information from failure symptoms from programmers&apos; replies to its questions. Therefore, it can operate without a line-by-line specification and a knowledge base of faults. A prototype o

Efficacy and Feasibility of the Minimal Therapist-Guided Four-Week Online Audio-Based Mindfulness Program &lsquo;Mindful Senses&rsquo; for Burnout and Stress Reduction in Medical Personnel: A Randomized Controlled Trial

Previous online mindfulness-based interventions for burnout and stress reduction in medical personnel had limited effect size and high dropout rate, so we developed a new online mindfulness program &lsquo;Mindful Senses (MS)&rsquo; with aims to increase effect size and lower dropout rate. To test its efficacy and feasibility, ninety medical personnel with moderate or high levels of burnout and stress from across Thailand were recruited and randomly allocated into Group A and Group B equally. Group A read psychological self-help articles (PSA) and attended MS program through smartphone application during weeks 1&ndash;4. Group B read PSA during weeks 1&ndash;4 and attended MS program during weeks 9&ndash;12. Burnout, stress, anxiety, depression, mindfulness, and quality of life were measured at baseline, week 4, and week 8 for both groups, and at weeks 12 and 16 for Group B. Group x time interaction was analyzed by repeated-measures ANOVA. The results showed that, compared to PSA only, MS + PSA had statistically significant improvement of burnout, stress, anxiety, depression, mindfulness, and quality of life with moderate-to-very large effect sizes at week 4 (d = 1.33, 1.42, 1.04, 1.14, 0.70, and 1.03, respectively) and moderate-to-large effect sizes at week 8 (d = 0.84, 0.98, 0.73, 0.73, 0.66, and 0.94, respectively). The dropout rate was 4.4%. In conclusion, the MS program has potential to be an alternative intervention for medical personnel suffering from burnout and stress

Advancing mindfulness research through innovative Ecological Momentary Assessment approaches

There are many critical and unresolved questions regarding how mindfulness impacts daily life experiences. In the current review, we put forward the perspective that ecological momentary assessment (EMA) is a critical research tool to potentially address these questions and advance the field of mindfulness research, but also that it has yet to be fully harnessed, in terms of its key advantages. We highlight various ways by which EMA can be better integrated into mindfulness studies to investigate mindfulness mechanisms in daily life, including individual differences in the rates and patterns of mindfulness learning; the acute and long-term impact of practice experiences; the frequency, quality, and contextual factors that give rise to spontaneous mindfulness states; and the measurement and optimization of mindfulness intervention effects. We further discuss the integration of EMA approaches with both adaptive mindfulness interventions and ecological momentary mindfulness behavioral tasks, to enable simultaneous performance-based measurements and training of mindfulness across various times and contexts. Mindfulness researchers are encouraged to consider incorporating these flexible extensions of EMA methodology into their own work, so as to best combine the primary advantages of laboratory-based, naturalistic, and intervention approaches