Evaluation of influence of bone quality on onset of action and the volume of anesthetic solution required: An original research

Aim: To evaluate the drug volume and onset of action of local anesthetic agent in different bone densities. Methodology: Present study was conducted on 40 subjects (20 male and 20 female) between 25 to 50 years attending to Sibar Institute of Dental Sciences, A 1.8ml 2% lignocaine with adrenalin was injected in the buccal mucosa(1ml) and palatal mucosa (0.8ml) in desired site of evaluation in maxilla. The duration of onset of action in minutes and drug volume used in milliliters was evaluated, where mainly comparison was done between two different densities of bone (D2,D3) according to Misch classification. Results: Areas of maxillary which had a denser cortical bone (D2) needed more volume (1.8-3.6 ml) of local anaesthetic solution (mean ± sd= 2.98 ± 1.02) for achieving its mode of action and subsequently lead to numbness when compared to D3 bone which was more of a porous variety which needed less volume of anaesthetic solution (mean ± sd= 1.63± 0.78) to achieve results. The comparative result was statistically significant (P=0.037). Conclusion: The denser the bone, more time it would take to achieve adequate level of anesthesia