Atrial Fibrillation Treatment

Purpose: The purpose of this article is to compare the newer oral anticoagulants know as Non-vitamin K oral anticoagulants (NOACs) and Direct oral anticoagulants DOACs to Warfarin for the treatment of the nonvalvular cause of Atrial Fibrillation in specific patient populations. Method: A PubMed literature search was conducted. From the home page of PubMed, using the advanced search link, direct oral anticoagulant, non-vitamin K oral anticoagulant, atrial fibrillation, and stroke was typed into the search fields. After the review, a second search was done with non-vitamin K oral anticoagulant, direct oral anticoagulant, atrial fibrillation, warfarin, and stroke as key terms. Results: In total, 32 meta-analyses were reviewed. The most relevant and recent studies were included and categorized for relevance. Conclusion: Atrial fibrillation (AF) is a well-known and significant risk factor for a stroke. 1 For many years, warfarin and other Vitamin K antagonists have been used extensively for stroke risk reduction. However, warfarin\u27s disadvantage includes a narrow therapeutic range and a multitude of drug interactions.2 In the last decade, we have seen an increase in the availability of oral anticoagulation options that try to address warfarin\u27s disadvantages. NOACs and DOACs have emerged to be a safe, effective, and convenient option. Given the ease of dosing, they are rapidly becoming a treatment of choice.3 With the emergence of anticoagulation options, medical providers must individualize therapy to meet the needs of their patients

Model training tasks as a tool for the construction of training process for athletes in team sports

The paper substantiates the design of the training process of athletes in team sports during an annual training cycle on the basis of model training tasks. The model training tasks are developed along with micro-and mesocycles, periods, and annual cycle for preparation of elite female volleyball players. The ratio of the training means and various types of training loads in the periods of macrocycle were determined. Introduction of model training tasks into the training process in team sports allows to efficiently plan and optimize the preparation of athletes, as well as to implement the principle of individualization in the development of a coherent team