2 research outputs found
Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds
The article describes fabrication and properties of composite fibrous
scaffolds obtained by electrospinning of the solution of
poly({\epsilon}-caprolactone) and arginine in common solvent. The influence of
arginine content on structure, mechanical, surface and biological properties of
the scaffolds was investigated. It was found that with an increase of arginine
concentration diameter of the scaffold fibers was reduced, which was
accompanied by an increase of scaffold strength and Young modulus. It was
demonstrated that porosity and water contact angle of the scaffold are
independent from arginine content. The best cell adhesion and viability was
shown on scaffolds with arginine concentration from 0.5 to 1 % wt
Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study
In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different calcium phosphate targets (calcium phosphate tribasic (CPT), hydroxyapatite (HA), calcium phosphate monobasic, calcium phosphate dibasic dehydrate (DCPD) and calcium pyrophosphate (CPP) powders). The sputtering of calcium phosphate monobasic and DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. The physico-chemical, mechanical and biological properties of the coatings were investigated. Cell adhesion on the coatings was examined using mesenchymal stem cells (MSCs). The CPT coating exhibited the best cell adherence among all the samples, including the uncoated zirconia substrate. The cells were spread uniformly over the surfaces of all samples