3 research outputs found
Application of Platelet Rich Fibrin and Osseomold Bone Graft in Different Intrabony Defects – 2 Case Reports
ABSTRACT: Aims & objectives: The motto behind any periodontal treatment is arrest of periodontal disease and regeneration of lost periodontium. Various treatment strategies have been employed in treatment of intrabony defects, but the best way to obtain regeneration is probably by mimicking the actual occurring events that takes place in the formation of the periodontal tissues at embryonic stage. Conventional open flap debridement falls short of regenerating tissues destroyed by the disease and current regenerative procedures offer a limited potential towards attaining complete periodontal regeneration.Platelet rich fibrin (PRF), a second generation platelet concentrate is widely used in osseous regeneration.Case description: The present study aimed to explore the clinical and radiographical effectiveness of autologous PRF along with the osseomold bone graft in treatment of 2 different cases of intrabony defects in chronic periodontics subjects.Conclusion: Among the 2 subjects, case-1 had 2-wall defect and case-2 patient had 3-wall defect. Both the subjects reported to the department with a complaint of food impaction and with clinically accessible >7-8mm pocket. Pocket depth was assessed at 1st week, 6months and 9months respectively and radio graphically bone gain was accessed at 3 month and 6 months
The influence of cigarette smoking on blood and salivary super oxide dismutase enzyme levels among smokers and nonsmokers—A cross sectional study
To determine the influence of smoking on blood and salivary superoxide dismutase enzyme levels among smokers, and to demonstrate the significant alterations in the levels of superoxide dismutase in association with patient age, periodontal disease status, smoking duration, and smoking frequency. This study also aimed to evaluate the use of saliva as a biological fluid for disease diagnosis.
Ninety males aged 25–56 years were selected and included 30 smokers, 30 nonsmokers with chronic periodontitis, and 30 healthy controls. Clinical parameters such as the gingival index, pocket depth, and clinical attachment loss were recorded. Blood and saliva samples were collected and superoxide dismutase enzyme levels were analyzed using spectrophotometric assay.
Superoxide dismutase enzyme levels in the blood and saliva were significantly higher in smokers than in nonsmokers and the controls (p < 0.05). A significant correlation existed between superoxide dismutase levels and clinical parameters. There was also a significant positive correlation between blood and salivary superoxide dismutase levels among the three groups.
Systemic and local antioxidant status is affected by periodontal disease and by the impact of smoking. The increased blood and salivary superoxide dismutase enzyme levels in smokers may be an adaptive defense mechanism to counteract the increased reactive oxygen species production induced by smoking. This study emphasizes the importance of saliva as an easy noninvasive tool in diagnosing patients who are more prone to precancerous lesions and conditions, and its importance in patient education and motivation programs for smoking cessation
Estimation and correlation of salivary thiocyanate levels in healthy and different forms of tobacco users having chronic periodontitis: A cross-sectional biochemical study
Background: Periodontitis is a common inflammatory disease with complex and multi-factorial origin. Tobacco usage has shown its adverse effect on periodontal health. Various components within saliva not only protect the integrity of oral tissues, but also provide clues to local and systemic diseases and conditions. Salivary thiocyanate (SCN) has been shown to be a chemical indicator in smokers and smokeless tobacco users. Noninvasive nature of salivary testing has made it an attractive and effective alternative to blood and urine testing. Limited studies are there comparing and correlating the salivary SCN levels in smokers with chronic periodontitis (CP). However, no studies show correlation of salivary SCN among gutka chewers with CP. Aims and Objectives: The objective of the following study is to estimate, compare, and correlate the SCN levels in periodontally healthy, CP, smokers with CP and gutka chewers with CP subjects. Materials and Methods: Study includes 120 subjects with age 18-55 years, categorized as periodonally healthy (n = 30), CP (n = 30), smokers (n = 30), and gutka chewers (n = 30) with CP. Required clinical parameters such as gingival index, probing depth and clinical attachment loss were recorded and salivary SCN levels were estimated through ultraviolet-spectrophotometer. Results: Mean salivary SCN level were shown to be higher among smokers and gutka chewers with CP as compared to healthy and CP alone. Conclusion: The present study exhibited the significant increase in salivary SCN levels among smokers and gutka chewers when compared to others, concluding that the analysis of salivary SCN levels could be used as an adjunctive means of diagnosis