SERVICE MARKETING MIX OF INDIAN HOSPITALS: A CRITICAL REVIEW

Abstract: Sreenivas

SERVICE MARKETING MIX OF INDIAN HOSPITALS: A CRITICAL REVIEW

Abstract Sreenivas

Diversity-Oriented Synthesis of Novel Benzimidazoles as Antimalarial agents via post Ugi MCR

An efficient strategy for the syntheses of highly diverse benzimidazoles in exceptional yields via post Ugi reactions has been described. In our methodology we have utilized isocyanide based Ugi-reaction followed by acid catalyzed condensation cyclization reaction under microwave irradiations. All benzimidazole derivatives showed moderate to good antimalarial activity when compared with chloroquine as reference compound. Among these compounds, three of them (8b), (8c), (8d) were found to be most potent towards antimalarial activity. The synthesized hybrids were examined for their purity with the help of thin layer chromatography. Different analytical techniques were employed for further characterization like Mass studies, NMRs (1H and 13C) and FT-IR

Antagonistic Potential of Native Trichoderma viride Strain against Potent Tea Fungal Pathogens in North East India

Indigenous strains of Trichoderma species isolated from rhizosphere soils of Tea gardens of Assam, north eastern state of India were assessed for in vitro antagonism against two important tea fungal pathogens namely Pestalotia theae and Fusarium solani. A potent antagonist against both tea pathogenic fungi, designated as SDRLIN1, was selected and identified as Trichoderma viride. The strain also showed substantial antifungal activity against five standard phytopathogenic fungi. Culture filtrate collected from stationary growth phase of the antagonist demonstrated a significantly higher degree of inhibitory activity against all the test fungi, demonstrating the presence of an optimal blend of extracellular antifungal metabolites. Moreover, quantitative enzyme assay of exponential and stationary culture filtrates revealed that the activity of cellulase, β-1,3-glucanase, pectinase, and amylase was highest in the exponential phase, whereas the activity of proteases and chitinase was noted highest in the stationary phase. Morphological changes such as hyphal swelling and distortion were also observed in the fungal pathogen grown on potato dextrose agar containing stationary phase culture filtrate. Moreover, the antifungal activity of the filtrate was significantly reduced but not entirely after heat or proteinase K treatment, demonstrating substantial role of certain unknown thermostable antifungal compound(s) in the inhibitory activity