A New Source Of Carbon Oxides In Biochemical Systems. Implications Regarding Dioxetane Intermediates

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The peroxidase catalyzed aerobic oxidation of aromatic pyruvates produces the aromatic aldehyde, oxalate, CO and CO2 and a weak light emission. This indicates the preliminary formation of a peroxy anion which can cyclizes to a four-membered ring dioxetane and to a five membered ring α-keto-β-peroxylactone intermediates. The possible importance of this new source of carbon oxides in biological systems is pointed out. The results considerably strengthen the view that a dioxetane is formed in side chain of the plant hormone indoleacetic acid during the oxidation catalyzed by peroxidase. © 1980.92132372006/05892-3; FAPESP; São Paulo Research FoundationFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Cilento, Durán, Zinner, Vidigal, Faria Oliveira, Haun, Faljoni, Bechara, CHEMIENERGIZED SPECIES IN PEROXIDASE SYSTEMS (1978) Photochemistry and Photobiology, 28, pp. 445-451Cilento, (1979) Photochem. Photobiol. Rev, , (in the press)Wilson, (1976) Int. Rev. Sci.: Phys. Chem. Ser. Two, 9, pp. 265-322Adam, (1977) Adv. Heterocyclic Chem, 21, pp. 437-481Horu, Koo, Schmidt, Schuster, (1978) Mol. Photochem, 9, pp. 1-37Ishikawa, Schubert, Nord, (1963) Biochem. Z, 338, pp. 153-163Zinner, Durán, Vidigal, Shimizu, Cilento, (1976) Arch. Biochem. Biophys, 173, pp. 58-65Chen, Gholson, Raica, (1974) Biochim. Biophys. Acta, 343, pp. 167-172Cook, Henderson, (1969) Biochim. Biophys. Acta, 184, pp. 404-411Zinner, Casadei de Baptista, Cilento, (1974) Biochem. Biophys. Res. Commun, 61, pp. 889-898Cilento, Nakano, Fukuyama, Suwa, Kamiya, (1974) Biochem. Biophys. Res. Commun, 58, pp. 296-300Jefford, Knőpfel, Cadby, (1978) Tetrahedron Letters, 38, pp. 3585-3588Jefford, Knőpfel, Cadby, (1978) J. Amer. Chem. Soc, 100, pp. 6432-6436Troxler, An Inexpensive Technique for Measuring Carbon Monoxide Formation in Plants (1971) PLANT PHYSIOLOGY, 48, pp. 376-378. , See also references cited thereinMiyahara, Takahashi, (1971) J. Biochem, 69, pp. 231-233Conn, Seki, (1957) Fed. Proc, 16, p. 167Vidigal, Zinner, Durán, Bechara, Cilento, (1975) Biochem. Biophys. Res. Commun, 65, pp. 138-145Durán, Zinner, Vidigal, Cilento, Generation of electronically excited aromatic aldehydes in the peroxidase catalyzed aerobic oxidation of aromatic acetaldehydes (1977) Biochemical and Biophysical Research Communications, 74, pp. 1146-115