3 research outputs found

    Regional association plot of the 1q24.1 risk locus.

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    <p>The figure shows −log<sub>10</sub><i>P</i> values (y-axis) versus chromosomal positions (x-axis; NCBI build 37). Genotyped SNPs are shown as triangles, with imputed SNPs as circles. rs3845536 has been highlighted through the use of a larger symbol. Colour intensity is proportional to LD with rs3845536: from white (<i>r</i><sup>2</sup> = 0) to red (<i>r</i><sup>2</sup> = 1.0). The light blue line indicates genetic recombination rates (estimated from 1000 Genomes Phase 1 CEU data). Nearby genes and transcripts are also shown.</p

    Novel and previously identified BMI and WHR<sub>adjBMI</sub> loci at <i>P</i> < 5×10<sup>−8</sup> in African ancestry discovery and replication samples, and European ancestry replication samples.

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    <p>Novel and previously identified BMI and WHR<sub>adjBMI</sub> loci at <i>P</i> < 5×10<sup>−8</sup> in African ancestry discovery and replication samples, and European ancestry replication samples.</p

    Additional novel BMI and WHR<sub>adjBMI</sub> loci at <i>P</i> < 5×10<sup>−8</sup> in sex-stratified analyses of African ancestry discovery and replication samples.

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    <p>Additional novel BMI and WHR<sub>adjBMI</sub> loci at <i>P</i> < 5×10<sup>−8</sup> in sex-stratified analyses of African ancestry discovery and replication samples.</p
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