7,692 research outputs found

    Explorer Satellite Electronics

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    A discussion is presented of the design restrictions and the philosophy which enabled the Explorer satellites to be first during the IGY to reveal the presence of a belt of intense cosmic radiation encircling the earth's equator. In addition, an indication of the amount and momentum of cosmic dust in the solar system was obtained from the Explorers. Methods used to obtain reliability in the transducing and communications system are described, together with interpretations of space-environment information as deduced from the narrow-band telemetry

    Public Involvement in research within care homes: Benefits and challenges in the APPROACH Study

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    Public involvement in research (PIR) can improve research design and recruitment. Less is known about how PIR enhances the experience of participation and enriches the data collection process. In a study to evaluate how UK care homes and primary health care services achieve integrated working to promote older people’s health, PIR was integrated throughout the research processes. Objectives This paper aims to present one way in which PIR has been integrated into the design and delivery of a multi-site research study based in care homes. Design A prospective case study design, with an embedded qualitative evaluation of PIR activity. Setting and Participants Data collection was undertaken in six care homes in three sites in England. Six PIR members participated: all had prior personal or work experience in care homes. Data Collection Qualitative data collection involved discussion groups, and site-specific meetings to review experiences of participation, benefits and challenges, and completion of structured fieldwork notes after each care home visit. Results PIR members supported: recruitment, resident and staff interviews and participated in data interpretation. Benefits of PIR work were resident engagement that minimised distress and made best use of limited research resources. Challenges concerned communication and scheduling. Researcher support for PIR involvement was resource intensive. Discussion and Conclusions Clearly defined roles with identified training and support facilitated involvement in different aspectsPublic Involvement in Research members of the research team: Gail Capstick, Marion Cowie, Derek Hope, Rita Hewitt, Alex Mendoza, John Willmott. Also the involvement of Steven Iliffe and Heather Gag

    Genetic Structure of Mongolic-Speaking Kalmyks

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    This is the publisher's version, also available electronically from http://digitalcommons.wayne.edu/humbiol/vol73/iss6/4.Genetic polymorphisms of blood groups ABO and RH D, serum proteins HP, TF, and GC, and red cell enzymes ACP1, PGM1, ESD, GLO1, and SOD-A have been reported for three tribes (Torguts, Derbets, and Buzavs) of the Volga’s Kalmyk-Oyrats. The Kalmyks exhibit genetic markers that are characteristic of Central Asian populations, namely, high allelic frequencies for ABO*B, TF*C2, GC*1F, ESD*2, and GLO1*2, and the rare incidence of individuals with the RH-negative phenotype. Genetic distance measures reveal that close genetic affinities exist between the Derbets and Buzavs, but both populations differ significantly from the Torguts. Collectively as an ethnic group, the Kalmyks genetically resemble the contemporary Buryats of the Baikal region of southeastern Siberia and the Mongols of Mongolia. The transplantation of the Kalmyk-Oyrats from their homeland near Lake Baikal to their current residence (4500 km) near the Caspian Sea and their subsequent isolation for more than 300 years have not appreciably altered the gene frequencies from the parental populations for frequencies of standard genetic markers

    Resonant Faraday and Kerr effects due to in-gap states on the surface of a topological insulator

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    When Dirac electrons on the surface of a topological insulator are gapped, the resulting quantum anomalous Hall effect leads to universal magneto-optical Faraday and Kerr effects in the low-frequency limit. However, at higher frequencies different excitations can leave their own fingerprints on the magneto-optics and can therefore be probed. In particular, we investigate the role of localized in-gap states - which inevitably appear in the presence of charged impurities - on these higher-frequency magneto-optical effects. We have shown that these states resonantly contribute to the Hall conductivity and are magneto-optically active. These in-gap states lead to peculiar resonant signatures in the frequency dependence of the Faraday and Kerr angles, distinct in character to the contribution of in-gap excitonic states, and they can be probed in ellipsometry measurements

    Pattern of Pathogens and Their Sensitivity Isolated from Surgical Site Infections at the Aga Khan University Hospital, Nairobi, Kenya

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    Background: In low income countries, surgical site infections (SSIs) are costly and impose a heavy and potentially preventable burden on both patients and healthcare providers. This study aimed to determine the occurrence of SSI, pathogens associated with SSI, the antibiogram of the causative pathogens and specific risk factors associated with SSI at the hospital. Methods: Two hundred and sixty-eight respondents admitted for general surgical procedures (other than neurological and cardiothoracic surgeries) at the Aga Khan University Hospital were eligible to take part in the study. Post-surgery patients were observed for symptoms of infection. Follow ups were done through the consulting clinics, breast clinic and casualty dressing clinic by a team of surgeons. In cases of infection, pus swabs were collected for culture.Results: SSI incidence rate was 7.0%, pathogens isolated from SSI included gram negative enteric bacilli and S. aureus which was the most prevalent bacterial isolate. Only one isolate of MRSA was found and all staphylococci were susceptible to Vancomycin. Preoperative stay ≥ 2 days and wound class were the risk factors associated with SSI.Conclusions: The SSI incidence rates (7.0%) observed in this study were relatively lower than the ones documented in other studies in Kenya. S. aureus is the most prevalent pathogen associated with SSI. Similar to findings from other studies done in the region; prolonged hospital stay and dirty wounds were the risks associated with postsurgical sepsis at the hospital.Keywords: Surgical sites, Infection, Surveillance, Antibiotic

    Optical Signatures of Circumstellar Interaction in Type IIP Supernovae

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    We propose new diagnostics for circumstellar interaction in Type IIP supernovae by the detection of high velocity (HV) absorption features in Halpha and He I 10830 A lines during the photospheric stage. To demonstrate the method, we compute the ionization and excitation of H and He in supernova ejecta taking into account time-dependent effects and X-ray irradiation. We find that the interaction with a typical red supergiant wind should result in the enhanced excitation of the outer layers of unshocked ejecta and the emergence of corresponding HV absorption, i.e. a depression in the blue absorption wing of Halpha and a pronounced absorption of He I 10830 A at a radial velocity of about -10,000 km/s. We identify HV absorption in Halpha and He I 10830 A lines of SN 1999em and in Halpha of SN 2004dj as being due to this effect. The derived mass loss rate is close to 10^{-6} Msun/yr for both supernovae, assuming a wind velocity 10 km/s. We argue that, in addition to the HV absorption formed in the unshocked ejecta, spectra of SN 2004dj and SN 1999em show a HV notch feature that is formed in the cool dense shell (CDS) modified by the Rayleigh-Taylor instability. The CDS results from both shock breakout and radiative cooling of gas that has passed through the reverse shock wave. The notch becomes dominant in the HV absorption during the late photospheric phase, ~60 d. The wind density deduced from the velocity of the CDS is consistent with the wind density found from the HV absorption produced by unshocked ejecta.Comment: 38 pages, 12 figures, ApJ, in pres
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