144 research outputs found

    Les motifs d’entrée en formation des adultes en reprise d’études universitaires

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    Un nombre croissant d’adultes retourne à l’université pour des motifs pluriels et souvent méconnus. La présente recherche vise à valider une adaptation de l’échelle descriptive des motifs d’engagement en formation développée par Carré (2001), qui concernait des formations professionnelles mais pas universitaires. Pour ce faire, 300 adultes en reprise d’études à l’université se sont exprimés par questionnaire quant à leurs motifs d’entrée en formation. Une analyse factorielle exploratoire a révélé certains motifs de la taxonomie de Carré. Dans l’ordre d’importance, il s’agit des motifs épistémiques, identitaires, vocationnels et opératoires professionnels. Cette structure est confirmée par un modèle en équations structurales.More and more adults undertake a university program for different reasons that are often unknown. The goal of this paper is to validate the adaptation of the descriptive scale measuring adults’ motives developed by Carré (2001), which referred to vocational training but not university programs. We asked 300 adults undertaking a university program to answer a questionnaire about their entry motives. A factor analysis yielded some motives of Carré’s taxonomy. In order of importance, these motives were epistemic, self-promotion, vocational and professional operatory. This structure is confirmed by a structural equation model

    Activités des enzymes puriques et pyrimidiques dans le diagnostic et le pronostic des leucémies lymphoïdes et des lymphomes

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    Doctorat en sciences médicalesinfo:eu-repo/semantics/nonPublishe

    Activités des enzymes puriques et pyrimidiques dans le diagnostic et le pronostic des leucémies lymphoïdes et des lymphomes

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    Doctorat en sciences médicalesinfo:eu-repo/semantics/nonPublishe

    Methylthioadenosine phosphorylase and purine nucleoside phosphorylase in B-chronic lymphocytic leukemia

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    Enzymes of purine metabolism have potential utility as biological markers of normal lymphocytes and their neoplastic counterparts. The activity of two of them, methylthioadenosine phosphorylase (MTA phosphorylase) and purine nucleoside phosphorylase (PNP) were measured in peripheral mononuclear cells from 11 patients with B-chronic lymphocytic leukemia (B-CLL) and compared with those obtained in cells from 10 normal volunteers. An inverse relationship between the two phosphorylases was demonstrated in patients, with higher MTA-phosphorylase and lower PNP activities than in control subjects.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Refugee camps in Somalia: a micro survey (March 1980)

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    Twenty-seven percent of the children of 1-6 years were in a state of moderate malnutrition and 5% were suffering from severe malnutrition; 14% of the mothers had severe anaemia, probably originating in multiple deficiences. Poor sanitary conditions, due mainly to overcrowding, the high morbidity, fluctuations in food supply and the low level of the basic food allowance, would seem to be sufficient to explain the observed pattern and prevalence of infection and malnutrition. -from AuthorsSCOPUS: NotDefined.jFLWNAinfo:eu-repo/semantics/publishe

    Erythrocyte vitamin E is oxidized at a lower peroxide concentration in neonates than in adults

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    Erythrocytes of neonates and adults were incubated with increasing concentrations of H2O2 in the presence of a catalase inhibitor and in the absence of glucose; the pattern of oxidation of vitamin E was analyzed in relationship to that of glutathione, hemoglobin, and polyunsaturated fatty acids (PUFA), and in relationship to hemolysis. The changes of these various parameters were analyzed in function of H2O2 concentration and in relation to incubation time, and were compared in erythrocytes from neonates and adults. In the absence of H2O2, erythrocyte glutathione and tocopherol levels were similar in neonates and adults, despite fourfold lower serum vitamin E level in neonates; α-tocopherolquinone, methemoglobin, and malonyldialdehyde (MDA) were not detectable. At 0.375 mmol/L of H2O2, glutathione was completely oxidized. Erythrocyte α-tocopherol remained unchanged up to 0.75 mmol/L of H2O2, then decreased linearly, with increasing H2O2 concentrations to 10% of its initial value at 1.5 mmol/L of H2O2 in erythrocytes from neonates, whereas those from adults required 2.0 mmol/L of H2O2 (P < .05) for the same level of oxidation. The formation of α-tocopherolquinone appeared inversely related to the decrease of α-tocopherol. The incubation time did not influence the level of vitamin E oxidation. MDA was generated autocatalytically and resulted in hemolysis at 1.5 mmol/L of H2O2 in erythrocytes from neonates and at 3.5 mmol/L of H2O2 in erythrocytes from adults (P < .001). After four hours of incubation, MDA reached a plateau at a greater level (365 + 46 nmol/L) in cells of neonates than in those of adults (208 ± 37 nmol/L/mL) (P < .001). Hemogloblin was oxidized in the same pattern in erythrocytes of neonates and adults, and 90% of it was oxidized at 0.625 mmol/L of H2O2. In conclusion, in the experimental conditions used, oxidation of glutathione precedes that of vitamin E, and tocopherol is the last antioxidant to be consumed before the autocatalytic generation of MDA. Differences in the pattern of vitamin E oxidation, MDA generation, and hemolysis in erythrocytes from neonates and adults may be due to a lower erythrocyte vitamin E-PUFA ratio in neonates.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Activité anti-oxydante erythrocytaire et plasmatique dans le diabète de type I

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    Purine enzyme levels in rheumatoid arthritis

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    SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Électrophorèse capillaire et hémoglobinopathies

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    For 20 years, capillary electrophoresis has become a major tool in clinical laboratories. In protein analysis, the great diversity of separation principles has allowed it to replace classical electrophoresis and to compete with liquid chromatography. Since the very beginning, this technique has been applied to haemoglobin analysis, firstly to separate abnormal forms, then to quantify minor fractions. This article reviews the different capillary electrophoresis methods that have been developed for the separation and the quantification of hemoglobin fractions or of its basic elements. © 2005 Elsevier SAS. Tous droits réservés.SCOPUS: re.jinfo:eu-repo/semantics/publishe
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