Additional Medical Support of Antibiotic Therapy: the Need or Polypharmacy? Part 2

The article deals with the questions of efficacy and safety of antibacterial agents use, as well as the tactics of prevention of drug allergy in patients receiving antibiotics. The algorithm of the doctor’s actions when taking a decision on the administration of the antibiotic to the child is provided

Additional Medical Support of Antibiotic Therapy: the Need or Polypharmacy? Part 1. Probiotics

The paper presents an analysis of the results of current researches on the need, effectiveness and safety of additional pharmacological prevention for adverse events associated with the use of antibiotics in children. The authors conclude that because the positions of initial antibacterial agents for use in children in Ukraine are clearly, in a graded sequence defined by national protocols, and the efficacy and safety of probiotic use for the prevention of antibiotic-associated diarrhea in children has not been determined, the only way out of this situation is rational choice of first-line antibiotic

The myocardium functional reserve indicators in junior children with recurrent acute upper respiratory tract infection

Background. The problem of early diagnosis of cardiovascular diseases in children is relevant throughout the world and in Ukraine, as in childhood the health and quality of life of an adult are formed. The psychoemotional stress in junior children as well as increasingly complicating school curriculum, information overload with electronic gadgets, increased frequency of colds in children cause physical inactivity. In addition, infectious agents have a toxic effect on the myocardium, altering its functional state. All these together adversely affect the formation and development of the cardiovascular and respiratory systems of children. The aim was to study the functional reserve of the myocardium in junior children, depending on the frequency of upper respiratory tract infection (URTI). Materials and methods. The study examined 1109 children aged 6 to 9 years old. The URTI incidence was analyzed depending on the age. In the study, the children were divided into two groups. Group 1 consisted of the children with URTI — 210. Group 2 involved the children with occasional URTI — 899. Results. Among 210 surveyed children with upper respiratory infections 171 schoolboys (81.4 %) had reduced functional reserve of the myocardium, which is consistent with findings from other studies. In children aged 7 and 9 years old, the number of reduced functional reserve of the myocardium varies from 70 to 82 % in seven-year children, among the schoolboys aged 6 and 8 years old the incidence of reduced functional reserve of the myocardium increased from 83 to 100 % in six-year children. Conclusions. Children with URTI have a reduced functional reserve of the myocardium. Children with episodic URTI have higher rates of functional reserve of the myocardium, therefore reducing the incidence of URTI will lead to the improvement of the myocardium functional state

The influence of psycho-emotional stress in children of primary school age on the incidence of recurrent upper respiratory tract infections and the functional state of the myocardium

Background. Scientific and technical progress, intensification of educational process and information overload have a negative effect on unformed central nervous system of primary schoolchildren, causing stress, which affects the increase in the incidence of recurrent upper respiratory tract infections (URTI) and the functional state of the myocardium. In view of this, we analyzed a functional state of myocardium in children with recurrent URTI. The critical duration of the work of primary school child with electronic means of communication, which affects the quality of nighttime sleep and the nature of awakening in the morning, was established. We have studied the relationship of the above mentioned with the incidence of URTI, the level of school anxiety and functional reserve of the myocardium. The purpose of the study was to evaluate the functional reserve of the myocardium in children of primary school age, depending on the incidence of URTI and the level of psycho-emotional activity. Materials and me­thods. 239 children aged 6 to 9 years were examined. The analysis of the functional reserve of the myocardium was carried out in pupils with different incidence of the URTI, depending on the age. The influence of electronic communications on the quality of nighttime sleep and morning awakening was stu­died, and the level of school anxiety was evaluated. During the study, children were divided into two groups. Group 1 — children with recurrent acute respiratory diseases (n = 143). Group 2 — children who occasionally have URTI (n = 96). Results. Out of 239 children with recurrent acute respiratory infections, we have identified 173 children with reduced functional reserve of the myocardium (72.4 %). Among children with recurrent URTI, the incidence of reduced functional reserve of the myocardium was 76.2 %, and in occasionally ill children — 66.7 %. Children with recurrent URTI use electronic means of communication more often than occasionally ill children: a direct strong positive relationship was revealed between the decrease in the functional reserve of the myocardium and the time spent on gadgets as compared to children occasionally suffering from URTI. Conclusions. Children with recurrent URTI spend more time on electronic communication means than occasionally ill children. Among children with recurrent URTI, disturbances of night sleep and morning awakening are revealed most often. Children with recurrent URTI more often than occasionally ill children have high school anxiety. Prolonged use of electronic communication means, disturbances of night sleep and mor­ning awakening are accompanied by a decrease of functional reserve of the myocardium

Inhalation Forms of Ambroxol in the Therapy of Respiratory Tract Secretory-Evacuation Disorders in Acute Bronchitis in Children

The mucoactive therapy of children aged 1 to 5 years with acute bronchitis using drug Lasolvan solution for oral and inhalation use or syrup for oral use Lasolvan is highly effective and safe method for management of respiratory tract secretory-evacuation disorders. Given the chance of inhalation therapy, effective treatment of choice, while maintaining a high safety profile, is inhalation of Lasolvan solution for oral and inhalation use by nebulizer. More rapid decline in the clinical severity of acute bronchitis in children treated with inhaled Lasolvan associated with accelerated recovery of disturbed secretory-evacuation mechanisms of bronchial tree

Immunoregulating Potential of Omega 3 Fatty Acids: Usage for Frequent Infectious Diseases Prevention in Children

Last years more and more investigations aim to study immune modulating function of long-chain polyunsaturated fatty acids (LCPUFA) the usage of which in practice could prevent development of acute respiratory diseases and allergic states. Among majority of LCPUFA omega 3 fatty acids are of greater interest. The authors of this article review several stu­dies and represents own investigation of impact of dietary supplement with omega 3 fatty acids complex («Omegami Smart Kid») on acute respiratory diseases reduction in children with recurrent forms of acute respiratory infectious pathology. Immunotropic action of dietary supplement of «Omegami Smart Kid» in children was associated with enhanced functioning of congenital and adaptive immunity. Immunoregulating target was associated with limited pro-inflammatory inclination of immunity as a nitro blue tetrazolium reduction test improvement, decreased CD25 and serum content of tumor necrosis factor α while an absence of concurrent immune suppression of anti-microbial protective potential