8 research outputs found
Detection of fraudulent use of zeranol and natural occurence of zearalenone in cattle urine by high performance liquid chromatography
SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe
High performance liquid chromatographic determination of sulpiride (Dogmatil®) in urine
SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Degradation study of catecholamines, indole amines and some of their metabolites in different extraction media by chromatography and electrochemical detection
SCOPUS: ar.jinfo:eu-repo/semantics/publishe
High performance liquid chromatographic determination of some substituted benzamides in serum after ion-pairing extraction
SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe
Separation, identification and quantitative analysis of substituted benzamides in pharmaceutical dosage forms by high pressure liquid chromatography
Reverse phase high pressure liquid chromatography has been used to separate, identify and analyse five closely structurally related benzamides: procainamide, sultopride, tiapride, sulpiride and metoclopramide. The influence of various parameters on the separation (solvent composition, pH, type and concentration of the anion modifying the ionic strength of the buffer) has been examined. The results of this study suggest that the separation mode is similar to an ion pair partition chromatography in which the nature of the counter-ion is essential. The method has been applied successfully to the quantitative analysis of some of the above mentioned compounds in pharmaceutical dosage forms. © 1979.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
High performance liquid chromatographic capacity factor and partition coefficient relationship in a benzamide series
High performance liquid chromatography was used to establish the relationship between capacity factor (log k') and partition coefficient (log P octanol/water) in a benzamides series. The Chromatographie parameter was correlated to log P values experimentally determined by the shake-flask method and to log P calculated from Rekker's molecular fragments approach. In both cases, for the 10 molecules studied, capacity factor on partition coefficient fit very closely a regression line. The linear model was tested for another molecule in the same series. When comparing the computed values and the experimental ones, it can be concluded that HPLC is a good tool in predicting partition coefficient in this series. © 1981.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Toxicological analysis of phenylethylamines by high performance reversed-phase ion-pair partition thin-layer and liquid chromatographies
SCOPUS: ar.jinfo:eu-repo/semantics/publishe