An eating disorder randomized clinical trial and attrition: Profiles and determinants of dropout

Objective: This study sought to determine whether differential treatment effects in the targeted mechanisms of change and eating disorder (ED) symptoms are associated with patterns of attrition from a RCT. Method: The main study was a RCT of a psychotherapy designed to alter the non-weight related self-cognitions as the means to promote recovery and health in a sample of 69 women with AN or BN. Four groups based on point of dropout were compared on demographic, self-cognitions and ED symptoms using logit and piecewise mixed effects modeling. Results: Attrition was highest during treatment phase but no significant predictors were found. During the measurement phase, the direction and amount of change in self-cognition interrelatedness and body dissatisfaction differed according to point of dropout and treatment group. Discussion: Attention to changes both in symptoms and mediating factors that occur during treatment and follow-up may help to identify those who are at risk for dropout and to develop strategies to promote RCT participant retention. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:356–368)Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/83766/1/20800_ftp.pd