Chronic cervicitis in women of reproductive age: pathogenesis and treatment. A review

The issue of cervicitis and vulvovaginitis is relevant worldwide due to the increasing incidence in women of reproductive age. To date, the significant role of chronic cervicitis in the development of cancer and other diseases of the reproductive system, including cervical cancer, has been proven. In recent years, a number of large studies have been conducted, covering a significant part of the clinical issues, pathogenesis, and epidemiology of cervicitis. However, there is a clear need for further studies of both the etiological factors and the pathogenetic mechanisms of inflammatory cervical disease to support the treatment choice

Vaccinal Prevention of the Diseases Caused by Human Papillomavirus: Evidence-Based Medicine. Review of Clinical Guidelines

The article is devoted to the urgent problem of papillomavirus infection, the extremely high prevalence of which determines the key contribution to the structure of morbidity and mortality from oncological diseases. A chronic persistent course, resulting in benign and malignant tumors in the infection atrium, makes scientists seek new ways of treatment. A specific vaccinal prevention is recognized to be the only reliable protection method today. The article is an updated review of the clinical guidelines developed and approved by the professional association «Union of Pediatricians of Russia» in 2016 for a vaccinal prevention of the diseases caused by human papillomavirus, first published on pediatr-russia.ru. The widespread introduction of vaccines against human papillomavirus, which have confirmed the clinical efficacy and safety, can significantly reduce the global burden of diseases associated with papillomavirus infection