Cyclic voltammetric oxidation of p-nitro benzaldehyde

The oxidation of 4-nitro benzaldehyde is studied in the medium of 60% acetic acid using platinum electrode by the cyclic voltammetry technique. The process of oxidation is found to be irreversible, involving two electron transfer. The rate constant for the charge transfer is obtained. The product of oxidation is identified by UV spectr

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

10.1371/journal.pone.0061893PLoS ONE85e6189

Design and application of a confocal microscope for spectrally resolved anisotropy imaging

Biophysical imaging tools exploit several properties of fluorescence to map cellular biochemistry. However, the engineering of a cost-effective and user-friendly detection system for sensing the diverse properties of fluorescence is a difficult challenge. Here, we present a novel architecture for a spectrograph that permits integrated characterization of excitation, emission and fluorescence anisotropy spectra in a quantitative and efficient manner. This sensing platform achieves excellent versatility of use at comparatively low costs. We demonstrate the novel optical design with example images of plant cells and of mammalian cells expressing fluorescent proteins undergoing energy transfer

Functionalised staple linkages for modulating the cellular activity of stapled peptides

10.1039/c4sc00045eChemical Science551804-1809CSHC