Gastric Pacing in a Child with Severe Gastroparesis and Review of the Literature

Gastroparesis is a disorder characterised by symptoms of and evidence for gastric retention in the absence of mechanical obstruction. Symptoms include nausea and vomiting, early satiety, postprandial fullness, regurgitation and abdominal pain. Common causes of gastroparesis are diabetes, post-surgical and idiopathic. In some patients, gastroparesis can be very severe and refractory to medical therapy including anti-emetics, anti-reflux and pro-kinetic medications. Gastric electrical stimulation represents a novel treatment for severe gastroparesis by regulating gastric electrical dysfunction with a neurostimulator. In adult studies, vomiting frequency has been reduced by up to 81% from baseline. We report a case of a 13-year-old girl with life-long severe idiopathic gastroparesis who was successfully treated by gastric pacing

Typhoid and Scrub Typhus Coinfection in a Returned Traveler

This is a case report of a 12-year-old returned traveler with typhoid and scrub typhus coinfection. The diagnosis of typhoid was made early with blood cultures and Widal Weil Felix serology. Persistent fever despite appropriate antibiotics for typhoid fever prompted a search for concomitant infection, which led to the diagnosis of scrub typhus confirmed by Orientia tsutsugamushi serology. The patient was given doxycycline with good clinical response. Scrub typhus infection should be an early consideration in the differential diagnoses of fever in a returned traveler from regions where it is endemic. Coinfections should be taken into consideration particularly when fever or symptoms persist despite adequate therapy for a previously identified microorganism

Obstructive Uropathy in a Child with Severe Chronic Constipation

Urinary symptoms are well-described in children with chronic constipation which include enuresis, urgency and recurrent urinary infections. Renal tract obstruction is a rare complication of severe chronic constipation. We describe a case of a 10-year-old boy with a history of long-standing constipation who presented with obstructive uropathy. Treatment strategies involved intensive medical therapy, parental education, behaviour modification strategies and close follow-up in a specialised constipation clinic. The obstruction was reversed and medications were discontinued after six months. Successful management of children with chronic constipation involves a multi-disciplinary approach in a specialised constipation clinic