Costa, Arthur L., and Richard A. Loveall, The Legacy of Hilda Taba, Journal of Curriculum and Supervision, 18(Fall, 2002), 56-62.

Gives contributions of Hilda Taba to the process of content selection and reports aspects of her professional career

Comments on the Bilderberg Continuum Atmosphere

The Bilderberg Continuum Atmosphere fails to reproduce the observed limb-darkening throughout the range of wavelengths 4500 Å< λ < 25 000 Å. The temperature-pressure diagram for the deep layers of this model is a curve which is flatter than the relation predicted from the mixing length theory. A modification of the Bilderberg Continuum Atmosphere that improves representation of the observations and theoretical results is proposed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43730/1/11207_2004_Article_BF00154247.pd

Presynaptic Plasticity as a Hallmark of Rat Stress Susceptibility and Antidepressant Response

Two main questions are important for understanding and treating affective disorders: why are certain individuals susceptible or resilient to stress, and what are the features of treatment response and resistance? To address these questions, we used a chronic mild stress (CMS) rat model of depression. When exposed to stress, a fraction of rats develops anhedonic-like behavior, a core symptom of major depression, while another subgroup of rats is resilient to CMS. Furthermore, the anhedonic-like state is reversed in about half the animals in response to chronic escitalopram treatment (responders), while the remaining animals are resistant (non-responder animals). Electrophysiology in hippocampal brain slices was used to identify a synaptic hallmark characterizing these groups of animals. Presynaptic properties were investigated at GABAergic synapses onto single dentate gyrus granule cells. Stress-susceptible rats displayed a reduced probability of GABA release judged by an altered paired-pulse ratio of evoked inhibitory postsynaptic currents (IPSCs) (1.48 ± 0.25) compared with control (0.81 ± 0.05) and stress-resilient rats (0.78 ± 0.03). Spontaneous IPSCs (sIPSCs) occurred less frequently in stress-susceptible rats compared with control and resilient rats. Finally, a subset of stress-susceptible rats responding to selective serotonin reuptake inhibitor (SSRI) treatment showed a normalization of the paired-pulse ratio (0.73 ± 0.06) whereas non-responder rats showed no normalization (1.2 ± 0.2). No changes in the number of parvalbumin-positive interneurons were observed. Thus, we provide evidence for a distinct GABAergic synaptopathy which associates closely with stress-susceptibility and treatment-resistance in an animal model of depression