5 research outputs found

    The role of the frozen section examination in the diagnosis of the thyroid nodules

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    Universitatea de Medicină și Farmacie Victor Babeș Timișoara, România, Al XIII-lea Congres al Asociației Chirurgilor „Nicolae Anestiadi” și al III-lea Congres al Societății de Endoscopie, Chirurgie miniminvazivă și Ultrasonografie ”V.M.Guțu” din Republica MoldovaIntroducere: Diagnosticul diferențial preoperator sau intraoperator între leziunile tiroidiene benigne și maligne este de o importanță majoră pentru decizia chirurgicală intraoperatorie. Acest studiu analizează corelația dintre rezultatul examenului extemporaneu și rezultatul examinării histopatologice la parafină în cazul nodulilor tiroidieni. Material si metode: Acesta a fost un studiu retrospectiv asupra a 330 de cazuri cu patologie tiroidiană, operate în cadrul Clinicii 2 de Chirurgie a Spitalului Clinic Județean de Urgență Timișoara din 2011 până în 2014, la care s-au efectuat atât examen extemporaneu intraoperator (EXT) cât și examen histopatologic la parafină în cadrul Departamentului de Anatomo-patologie al aceluiași spital. Rezultate: Din cele 330 de cazuri studiate, examenul EXT a stabilit diagnosticul în 244 (73,9%) cazuri și la 86 (26.1%) cazuri diagnosticul a fost incert, cu o sensibilitate de 93,33%, specificitate de 95,81%, în timp ce precizia a ajuns la 95,66%. Două sute douazeci și nouă (84,8%) au fost tumori benigne, iar 15 (27,3%) au fost tumori maligne. La examenul histopatologic, din 86 cazuri incerte 51 (59,3%) au fost benigne, 30 (34,8%) maligne și 5 (5,8%) au ramas neclare. Concluzii: Rezultatele noastre cu metoda EXT sunt echivalente cu cele disponibile în literatura de specialitate cu specificitate, sensibilitate si precizie foarte bune. În cazul în care investigațiile preoperatorii evidențiază noduli unilaterali, EXT a fost util pentru decizia intraoperatorie între lobectomie și tiroidectomie totală, evitând lobectomia inutilă sau reintervenția.Introduction: Preoperative or intraoperative differential diagnosis between benign and malignant thyroid lesions is of utmost importance for the surgical intraoperative decision. This study analyses the correlation between the frozen-section result and the result of the histopathologic paraffin examination in cases of thyroid nodules. Material and methods: This was a retrospective study upon 330 cases with thyroid pathology, operated on in the 2nd Surgical Clinic of the Clinical County Emergency Hospital of Timisoara from 2011 to 2014, that had both intraoperative frozen-section (FS) and postoperative paraffin histologic examination performed by the Pathology Department of the same hospital. Results: Of 330 cases studied, FS examination set the diagnosis in 244 (73.9%) cases and no diagnosis (uncertain) in 86 (26.1%), with a sensitivity of 93.33%, specificity of 95.81%, while accuracy reached 95.66%. Two hundred twenty-nine (84.8%) were benign tumors and 15(27.3%) were malignant tumors. At the histopathologic examination, from 86 uncertain cases 51 (59.3%) were benign, 30(34.8%) malignant and 5 (5.8%) remained unclear. Conclusions: Our results with FS method are equivalent to those available in the literature with very good specificity, sensitivity and accuracy. In cases in which the preoperative investigations show unilateral nodules, FS was still useful for the intraoperative decision between lobectomy and total thyroidectomy, avoiding inutile lobectomy or reoperation

    Hungry Bone Syndrome after parathyroidectomy in dialysis patients with secondary Hyperparathyroidism

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    Universitatea de Medicină și Farmacie Victor Babeș Timișoara, România, Al XIII-lea Congres al Asociației Chirurgilor „Nicolae Anestiadi” și al III-lea Congres al Societății de Endoscopie, Chirurgie miniminvazivă și Ultrasonografie ”V.M.Guțu” din Republica MoldovaIntroducere: Hiperparatiroidismul secundar (HPTS) s-ar putea dezvolta la aproape toți pacientii cu boala renală cronică în stadiu final (BRSF). O opțiune pentru tratamentul acestor pacienți este paratiroidectomia (PTX). Scopul acestui studiu este identificarea factorilor de risc pentru Hungry Bone Syndrome (HBS) la o cohortă de pacienți cu BRSF care au suferit PTX. Material si metode: Este un studiu retrospectiv pe 80 pacienți BRSF, la care s-a practicat PTX pentru HPTS în Clinica 2 Chirurgie a Spitalului Clinic Județean de Urgență Timișoara, pe perioada Ianuarie 2013 și Decembrie 2017. Indicația pentru PTX a fost HPTS refractară la tratamentul medicamentos sau complicațiile HPTS. Rezultate: HBS a aparut la 36 de pacienți, care au fost dializați pe perioada cuprinsă între șase luni și 14 ani, mediană de 7,2 ani. Preoperator valoarile PTH-ului au fost comparabile între cele două grupuri HBS + 1831pg/ml vs HBS-1880pg/ml. Vârsta a fost HBS +: HBS-52,4: 54. PTX subtotală (două glande) a fost efectuată în 18 cazuri, PTX subtotală 3½ glande a fost efectuat în 25, în timp ce PTX total în 37. Timectomia s-a efectuat la 19 cazuri. Hipocalcemia a aparut după 19,9 ore postoperator. Postoperator valoarea PTH-ului a arătat diferențe foarte mici între 72pg/ml și 87,1pg/ml. Singurii factori de risc pentru HBS s-au dovedit: vârsta mai mică (p = 0,038), prezența osteoporozei avansate (p = 0,017) și post-operator PTH (p = 0,005). Concluzii: HBS este un efect advers obisnuit, dificil predictibil, varsta mai mica, prezenta osteoporozei inainte de operatie. Nivelurile PTH-ului post-operator par sã favorizeze aparitia acesteia.Introduction: Secondary hyperparathyroidism (SHPT) was found to be a common complication of chronic kidney disease (CKD). Nearly all patients with end-stage renal disease (ESRD) might ultimately develop SHPT. In these cases which don’t respond to medical therapy, one option of treatment is parathyroidectomy (PTX). Our study aims to identify the risk factors for HBS in a cohort of ESRD patients which underwent PTX. Material and methods: This was a retrospective study on 80 ESRD parathyroidectomised patients for SHPT in Timisoara County Emergency Hospital between January 2013 and December 2017. Indication for parathyroidectomy was SHPT refractory to medical treatment or complications of SHPT. Results: HBS occurred in 36 dialyzed patients (ranging from half to 14 years, median 7.2 years). Pre-operative levels of PTH were comparable between the two groups HBS+ 1831 vs HBS- 1880. Mean age was 52.4 for HBS+ vs 54 for HBS-. Subtotal PTX (two glands) was performed in 18 cases, subtotal PTX 3 ½ glands was performed in 25, whereas total PTX in 37. Timectomy was performed in 19 cases. Hypocalcemia occurred after 19.9 hours post-operatively. PTH postoperative determination showed very small differences 72 pg/ml vs 87.1 pg/ml. The only risk factors for HBS were found to be younger age (p=0.038), the presence of advanced osteoporosis (p=0.017) and post-operator PTH (p=0.005). Conclusions: HBS is a common adverse effect. Younger age, osteoporosis presence before surgery and post-operative levels of PTH seem to favor its appearance. The magnitude of surgery does not influence the occurrence of HBS

    Behavioral Ecology of Cockroaches

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    WOS:A1984SP92200003International audience1. Cockroaches are ubiquitous in most habitats where insects occur. Although most reports on cockroaches are physiological in nature, sufficient information is available to indicate that forest, desert, and cave-dwelling cockroaches select microhabitats on the basis of finely resolved environmental preferences. This is particularly true for oviparous females which select specific substrates for oviposition and embryogenesis. Selection and diel movements between microhabitats are related to diel changes in micrometeorological profiles and predation, feeding, and enhancement of sexual communication.2. With some exceptions oviparous species live in wooded habitats; ovoviviparous species tend to occur in protected environments such as caves and logs. Oviparous species are exposed to greater predation, parasitism, and environmental pressures during embryogenesis than are ovoviviparous species, where internal incubation and some parental care reduce these risks. Most ovoviviparous species produce larger clutches, but the interval between broods is significantly longer than in oviparous species. Long gestation, clumping of food resources, and relatively little movement probably selected for male control of resources as a mate-attraction tactic in ovoviviparous species; agonistic interactions, and in some cases morphological specializations for fighting, and highly ritualized behaviours are common. In most oviparous species, volatile pheromone communication and resource-based aggregations are common. Rapid ovarian cycles and patchily distributed nutritional resources result in the need for greater mobility, and hence adults encounter greater risks
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