Complications with Pneumoniae in COVID-19 Patients at the First University Clinic of Tbilisi State Medical University, Georgia

COVID -19 virus can infect the lower respiratory tract and cause pneumonia in humans. This is associated with different health difficulties, prolonged hospitalization, high mortality rate and economical-financial problems as well.160 patients were admitted to First University Clinic of Tbilisi State Medical University, Georgia (March-June 2020). We conducted retrospective study to reveal the frequency of pneumonia among COVID -19 patients, specifically according to gender and age. Study results show that pneumonia was common in most COVID -19 cases (74.3%), that was more prevalent in females - 58%. Especially, high rate of this complication was reported in the age group of patients  between 30-59 years (47.8%) rather than in other age groups. 92.4% of pneumonia patients were recovered, lethal outcome was developed in 7.6% of cases

C reactive protein, Procalcitonin, Ferritin Levels in Mild, Severe and Critically Ill Patients with Coronavirus Disease 2019 (COVID-19)

The severe acute respiratory syndrome coronavirus-2 has infected millions of people worldwide, causing the COVID-19 pandemic. The pathogenic mechanism of infection is still under investigation.Due to lack of appropriate treatment, it is important to determine specific biomarkers to help clinicians identify patients at high risk of death, especially among those with severe COVID-19. These inflammatory factors may be prognostic biomarkers for predicting severe COVID-19 infection, therefore early identification of patients with COVID-19 with possible adverse prognostic factors is important for treatment and limiting severe outcomes and death.In the study we investigated the potential interdependence of some laboratory parameters - C reactive protein, procalcitonin, ferritin in different clinical severity COVID‐19 patients. Study results indicate that average values of these biomarkers vary in accordance with severity of COVID-19 infection. These values are explicitly higher in critically ill patients in comparison with mild and severe forms of disease

Interplay of Different Parameters in COVID‐19 Infection and Novel Results of Possible Prevention and Treatment (Review of the Literature)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) remains a global challenge. There are intense studies for finding effective prevention and treatment options worldwide. Therefore, infection prevention, prognostic parameters of infection complication and identification of successful treatment protocols need more investigations.Interpretation of laboratory parameters may support clinicians in prevention and treatment of the disease, will improve COVID 19 infection outcomes and may potentially decrease the death rate overall.Study results have shown that different laboratory parameters during the disease course are significantly changed. In critically ill patients, coagulation complications and coagulation/anticoagulation imbalance are characteristic also. According to the research results, vaccination offers the best option for COVID-19 control.In this review, some parameters, current therapeutic options, preventive methods of COVID 19 infection are discussed