Dendritic macromolecule and the preparation thereof

The invention relates to a dendritic macromolecule comprising a core and branches emanating from the core wherein the branches are based on vinyl cyanide and/or fumaryl dinatrile units. The invention also relates to processes for preparing these dendritic macromolecules. The dendritic macromolecules according to the invention are not sensitive to degradation through hydrolysis reactions and are also very stable at a high temperature. The processes are very suitable for large scale production of the dendritic macromolecules without requiring purification of reaction intermediates

Large-scale production of polypropylenimine dendrimers

Th synthesis and characterization of a new series of polypropylenimine (I) dendrimers is reported. Using a repetition of the sequence of a Michael addn. to a primary amine, followed by a heterogeneously catalyzed hydrogenation, ultra-pure polypropylenimine macromols. with mol. wts. £6912 are synthesized. The reaction sequence allows the prepn. of these dendrimers at very large scales, while the availability of a simple purifn. in the sequence affords ultra-pure samples. The I dendrimers are fully characterized; apart from the first 0.5 generation they are all oils, possess a glass transition temp. of -90° to -40°, and are unexpectedly stable. Their intrinsic viscosity drops after generation 4

Large-scale production of polypropylenimine dendrimers

Th synthesis and characterization of a new series of polypropylenimine (I) dendrimers is reported. Using a repetition of the sequence of a Michael addn. to a primary amine, followed by a heterogeneously catalyzed hydrogenation, ultra-pure polypropylenimine macromols. with mol. wts. £6912 are synthesized. The reaction sequence allows the prepn. of these dendrimers at very large scales, while the availability of a simple purifn. in the sequence affords ultra-pure samples. The I dendrimers are fully characterized; apart from the first 0.5 generation they are all oils, possess a glass transition temp. of -90° to -40°, and are unexpectedly stable. Their intrinsic viscosity drops after generation 4