An Enhanced Table Driven Source Routing Protocol for Wireless Ad Hoc Networks

Analysis of MANETs led to the research on network layer. Different routing protocols were designed for numerous objectives and purposes. The way data packets are handled with in a multi-hop wireless network refers to Opportunistic data forwarding. During present research, we propose enhanced table-driven source routing protocol. This protocol maintains additional topology information which is different from Distance Vector (DV) routing protocol. The proposed approach will reduce overhead compared to the ancient Distance Vector based protocols. Base on the test results performed using Computer Simulator (Network Simulator 2) observed that the overhead in the proposed solution is just a fraction of the overhead of the standard proactive protocols. Performance of the current solution is better for transportation of higher information compared to existing proactive routing protocols

An unusual branching pattern of the median cubital vein and its relations with lateral cutaneous nerve of forearm in the upper extremity: anatomicoclinical notes.

Cubital fossa is the usual site for performing venepuncture in the clinical settings for health screenings and diagnostic purposes. This procedure is simple and uncomplicated but occasionally can lead to bleeding and pain in the form of complex regional pain syndrome. Superficial veins of the upper limb are often used for venepuncture for transfusion purposes and for obtaining blood samples. These veins are also used for cardiac catheterisation and giving intravenous injections. During routine cadaveric dissection, a cubital venous variation was observed in a 45-yr –old, male cadaver. The median cubital vein initiated from cephalic vein passed upwards and laterally superficial to posterior branch of medial cutaneous nerve of forearm. In the middle of its course, it gave off an ascending channel which further divided into medial and lateral tributaries. The medial tributary terminated into the basilic vein, whereas the lateral tributary ascended laterally superficial to a branch of lateral cutaneous nerve of forearm and drained into cephalic vein at the level of elbow joint. Various patterns of superficial cubital veins have been mentioned in literature. Awareness of such anatomical variations is crucial while performing venepuncture in clinical settings as well as for creating arteriovenous fistulas for hemodialysis purpose

Power Allocation for Uniform Illumination with Stochastic LED Arrays

Light has traditionally been used for making objects visibl e to the naked eye. Lately, there has been tremendous interest in using it for free space communication [1]. This has simultaneously been accompanied by significant interest in light emitting diodes (LEDs) that have been replacing conventional light sources in almo st all applications [2–4]. Fair amount of existing literature has focused on achieving unif orm irradiance over a planar surface [5–8], beginning with the problem of finding the opti mal LED geometry at the light source to achieve uniform irradiance [9]. This was don e by using the irradiance distributions at the closest points on the incident surface . The case of LEDs using a freeform lens with a large view angle has been considered in [ 10]. More literature on similar themes is available in [11,12]

INVESTIGATION OF THE NEUROPROTECTIVE EFFECT OF LINAGLIPTIN AND CELIPROLOL IN RESERPINE-INDUCED OROFACIAL DYSKINESIA AND ROTENONE-INDUCED NEURODEGENERATION IN RATS

Objective: Linagliptin, an anti-diabetic agent, proven to play an important role in regulating neuronal plasticity and reduce apoptosis and neuroinflammation by activating downstream AMPK/Sirt 1 pathway, which protects mitochondrial function and suppresses intracellular ROS accumulation and shows antioxidant action. Celiprolol, a β-1selective adrenoceptor blocker used as an anti-hypertensive agent, possesses a direct scavenging activity on oxygen radicals with antioxidant properties. The current study was designed to investigate the combined neuroprotective effect of linagliptin and celiprolol. Methods: Wistar rats of either sex were divided into different groups (n = 6). Eight groups each for Reserpine induced orofacial dyskinesia model and Rotenone induced neurodegeneration model to mimic Parkinson’s like conditions and treated or not with different doses of linagliptin and celiprolol. 24 h after the last dose, animals were subjected to behavioral, biochemical and histopathological evaluations. The data were analyzed by ANOVA and Bonferroni multiple comparison test. Results: Reserpine treatment increased VCMs, tongue protrusion and decreased locomotor activity. Rotenone treatment decreases the motor activity and exploratory ability of the animals. Reserpine as well as rotenone treatments decrease catalase, GSH, SOD and increase the LPO levels as compared to sham group animals. Reserpine and rotenone also showed the presence of ghost cells and vacuolated cytoplasm. Linagliptin and celiprolol alone as well as in combination normalized the behavioral, biochemical and histopathological complications. Conclusion: Linagliptin and Celiprolol showed neuroprotection by antioxidant activity as well as improved reserpine and rotenone-induced behavioral deficits. Both drugs have tenacious potential and can be used clinically with some further investigations

PROTECTIVE EFFECT OF NEBIVOLOL ON ALUMINIUM-INDUCED NEUROBEHAVIORAL AND BIOCHEMICAL ALTERATIONS IN RATS

Objective: The present study was designed to investigate the neuroprotective potential of nebivolol, a β1 adrenergic blocker on aluminium-induced neurobehavioral and biochemical alterations in rats. Methods: The neurotoxicity was induced by administration of aluminium (50 mg/kg/day, p.o.) for 5 weeks. Nebivolol was administered at a dose of 10 mg/kg, p.o. for 5 weeks. Behavioral assessments were done by using open field test and modified elevated plus maze (mEPM) test. At the end of the study, oxidative stress parameters were determined and histopathological studies of cerebral cortex of rat brains were performed. Results: Aluminium chloride treated rats showed significant reduction in motor activity in open field test and memory impairment in mEPM test as compared to control group. Nebivolol significantly reversed these parameters and restored brain antioxidant defensive enzymes with reduction in lipid peroxidation. The neurotoxicity was confirmed by the histopathological analysis of cerebral cortex of rat brains. Aluminium treated animals showed presence of ghost cells, vacuolated cytoplasm and haemorrhage in rat cerebral cortex, indicating neurotoxicity. Nebivolol attenuated all these changes. Thus, the potential of nebivolol to prevent aluminium-induced neurotoxicity was also reflected at microscopic level, indicative of its neuroprotective effects. Conclusion: Nebivolol showed significant antioxidant and neuroprotective activities against aluminium-induced neuronal degeneration. The results of the present study strengthen oxidative stress hypothesis of aluminium-induced neurotoxicity and suggest beneficial role of nebivolol in the treatment of neurodegenerative disorders

Phase-plane analysis of driven multi-lane exclusion models

We show how a fixed point based boundary-layer analysis technique can be used to obtain the steady-state particle density profiles of driven exclusion processes on two-lane systems with open boundaries. We have considered two distinct two-lane systems. In the first, particles hop on the lanes in one direction obeying exclusion principle and there is no exchange of particles between the lanes. The hopping on one lane is affected by the particle occupancies on the other, which thereby introduces an indirect interaction among the lanes. Through a phase plane analysis of the boundary layer equation, we show why the bulk density undergoes a sharp change as the interaction between the lanes is increased. The second system involves one lane with driven exclusion process and the other with biased diffusion of particles. In contrast to the previous model, here there is a direct interaction between the lanes due to particle exchange between them. In this model, we have looked at two possible scenarios with constant (flat) and non-constant bulk profiles. The fixed point based boundary layer method provides a new perspective on several aspects including those related to maximal/minimal current phases, possibilities of shocks under very restricted boundary conditions for the flat profile but over a wide range of boundary conditions for the non-constant profile.Comment: 13 pages, 17 figure