119 research outputs found
Direct Stenting versus Conventional Stenting in Patients with ST-Segment Elevation Myocardial InfarctionâA COMPARE CRUSH Sub-Study
Background: Direct stenting (DS) compared with conventional stenting (CS) after balloon predilatation may reduce distal embolization during percutaneous coronary intervention (PCI), thereby improving tissue reperfusion. In contrast, DS may increase the risk of stent underexpansion and target lesion failure. Methods:In this sub-study of the randomized COMPARE CRUSH trial (NCT03296540), we reviewed the efficacy of DS versus CS in a cohort of contemporary, pretreated ST-segment elevation myocardial infarction (STEMI) patients undergoing primary PCI. We compared DS versus CS, assessing (1) stent diameter in the culprit lesion, (2) thrombolysis in myocardial infarction (TIMI) flow in the infarct-related artery post-PCI and complete ST-segment resolution (STR) one-hour post-PCI, and (3) target lesion failure at one year. For proportional variables, propensity score weighting was applied to account for potential treatment selection bias. Results: This prespecified sub-study included 446 patients, of whom 189 (42%) were treated with DS. Stent diameters were comparable between groups (3.2 ± 0.5 vs. 3.2 ± 0.5 mm, p = 0.17). Post-PCI TIMI 3 flow and complete STR post-PCI rates were similar between groups (DS 93% vs. CS 90%, adjusted OR 1.16 [95% CI, 0.56â2.39], p = 0.69, and DS 72% vs. CS 58%, adjusted OR 1.29 [95% CI 0.77â2.16], p = 0.34, respectively). Moreover, target lesion failure rates at one year were comparable (DS 2% vs. 1%, adjusted OR 2.93 [95% CI 0.52â16.49], p = 0.22). Conclusion:In this contemporary pretreated STEMI cohort, we found no difference in early myocardial reperfusion outcomes between DS and CS. Moreover, DS seemed comparable to CS in terms of stent diameter and one-year vessel patency.</p
Guilds in the transition to modernity: the cases of Germany, United Kingdom, and the Netherlands
One important aspect of the transition to modernity is the survival of elements of the Old Regime beyond the French Revolution. It has been claimed that this can explain why in the late 19th and early 20th centuries some Western countries adopted national corporatist structures while others transformed into liberal market economies. One of those elements is the persistence or absence of guild traditions. This is usually analyzed in a national context. This paper aims to contribute to the debate by investigating the development of separate trades in Germany, the United Kingdom and the Netherlands throughout the 19th century. We distinguish six scenarios of what might have happened to crafts and investigate how the prevalence of each of these scenarios in the three countries impacted on the emerging national political economies. By focusing on trades, rather than on the national political economy, our analysis demonstrates that in each country the formation of national political economies and citizenship rights was not the result of a national pattern of guild survival. Rather, the pattern that emerged by the end of the 19th century was determined by the balance between old and new industries, and between national and regional or local government
A emergĂȘncia dos conselhos setoriais na agroindĂșstria brasileira: gĂȘnese de uma governança mais ampla?
Serving a heterogeneous Muslim identity? Private governance arrangements of halal food in the Netherlands
Fossil trees from the basal Triassic Lebung Group at the Makgaba site, west of Mokubilo, Botswana
Fossil wood samples were collected from an area underlain by Karoo Supergroup rocks along the southern edge of Sua Pan in east central
Botswana. From the local stratigraphy it suggests that these fossils have been derived from the Mosu sandstones that occurs at the
base of the Mosolotsane Formation and which is time-equivalent to the Molteno Formation in South Africa that is of Triassic age. Based
on the arrangement of tracheid pits the fossil wood has been identified as Agathoxylon, and most likely Agathoxylon africanum. This
species has a Permian to Triassic time range in southern Africa and probably is the first published record of Agathoxylon africanum in
Botswana.https://www.wits.ac.za/esi/palaeontologia-africanaam2019Geolog
P366: ARE MINIMAL RESIDUAL DISEASE MEASUREMENTS AFTER CONSOLIDATION THERAPY USEFUL IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA?
"Knowledge Utilisation" in Dutch social policy: the case of the Disability Insurance Act (WAO)
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