A Topological Investigation of Phase Transitions of Cascading Failures in Power Grids

Cascading failures are one of the main reasons for blackouts in electric power transmission grids. The economic cost of such failures is in the order of tens of billion dollars annually. The loading level of power system is a key aspect to determine the amount of the damage caused by cascading failures. Existing studies show that the blackout size exhibits phase transitions as the loading level increases. This paper investigates the impact of the topology of a power grid on phase transitions in its robustness. Three spectral graph metrics are considered: spectral radius, effective graph resistance and algebraic connectivity. Experimental results from a model of cascading failures in power grids on the IEEE power systems demonstrate the applicability of these metrics to design/optimize a power grid topology for an enhanced phase transition behavior of the system

Clickstream Data and Inventory Management: Model and Empirical Analysis

We consider firms that feature their products on the Internet but take orders offline. Click and order data are disjoint on such non-transactional websites, and their matching is error-prone. Yet, their time separation may allow the firm to react and improve its tactical planning. We introduce a dynamic decision support model that augments the classic inventory planning model with additional clickstream state variables. Using a novel data set of matched online clickstream and offline purchasing data, we identify statistically significant clickstream variables and empirically investigate the value of clickstream tracking on non-transactional websites to improve inventory management. We show that the noisy clickstream data is statistically significant to predict the propensity, amount, and timing of offline orders. A counterfactual analysis shows that using the demand information extracted from the clickstream data can reduce the inventory holding and backordering cost by 3% to 5% in our data set

The first human experience of a contact force sensing catheter for epicardial ablation of ventricular tachycardia

Contact force (CF) is one of the major determinants for sufficient lesion formation. CF-guided procedures are associated with enhanced lesion formation and procedural success.We report our initial experience in epicardial ventricular tachycardia (VT) ablation with a force-sensing catheter using a new approach with an angioplasty balloon. Two patients with arrhythmogenic right ventricular cardiomyopathy who underwent prior unsuccessful endocardial ablation were treated with epicardial VTablation. CF data were used to titrate force, power and ablation time

SARS-CoV2 (COVID-19) infection: is fetal surgery in times of national disasters reasonable?

Even though the global COVID‐19 pandemic may affect how medical care is delivered in general, most countries try to maintain steady access for women to routine pregnancy care, including fetal anomaly screening. This means that, also during this pandemic, fetal anomalies will be detected, and that discussions regarding invasive genetic testing and possibly fetal therapy will need to take place. For patients, concerns about Severe Acute Respiratory Syndrome‐Corona Virus 2 will add to the anxiety caused by the diagnosis of a serious fetal anomaly. Yet, also for fetal medicine teams the situation gets more complex as they must weigh up the risks and benefits to the fetus as well as the mother, while managing a changing evidence base and logistic challenges in their healthcare system